General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 6117 |
Name | RPA1 |
Synonymous | HSSB|MST075|REPA1|RF-A|RP-A|RPA70;replication protein A1, 70kDa;RPA1;replication protein A1, 70kDa |
Definition | MSTP075|RF-A protein 1|RP-A p70|replication factor A protein 1|replication protein A 70 kDa DNA-binding subunit|single-stranded DNA-binding protein |
Position | 17p13.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
ATM | REACTOME; |
in same component |
ATRIP | NCI_NATURE; |
in same component |
ATRIP | REACTOME; |
in same component |
ATR | NCI_NATURE; |
in same component |
BLM | REACTOME; |
in same component |
BRCA1 | REACTOME; |
in same component |
BRCA2 | REACTOME; |
in same component |
CCNH | REACTOME; |
in same component |
CDC45 | REACTOME; |
in same component |
CDC6 | NCI_NATURE; |
in same component |
CDC6 | REACTOME; |
in same component |
CDC7 | REACTOME; |
in same component |
CDK2 | REACTOME; |
in same component |
CDK4 | REACTOME; |
in same component |
CDK7 | REACTOME; |
in same component |
CEP164 | NCI_NATURE; |
in same component |
CHEK1 | NCI_NATURE; |
in same component |
CLSPN | NCI_NATURE; |
in same component |
DBF4 | REACTOME; |
in same component |
DDB1 | REACTOME; |
in same component |
DDB2 | REACTOME; |
in same component |
DMC1 | REACTOME; |
in same component |
DNA2 | REACTOME; |
in same component |
ERCC1 | REACTOME; |
in same component |
ERCC2 | REACTOME; |
in same component |
ERCC3 | REACTOME; |
in same component |
ERCC4 | REACTOME; |
in same component |
ERCC5 | REACTOME; |
in same component |
GTF2H1 | REACTOME; |
in same component |
GTF2H2 | REACTOME; |
in same component |
GTF2H3 | REACTOME; |
in same component |
GTF2H4 | REACTOME; |
in same component |
H2AFX | REACTOME; |
in same component |
HIST3H3 | REACTOME; |
in same component |
HUS1 | NCI_NATURE; |
in same component |
HUS1 | REACTOME; |
in same component |
MCM10 | REACTOME; |
in same component |
MCM2 | REACTOME; |
in same component |
MCM3 | REACTOME; |
in same component |
MCM4 | REACTOME; |
in same component |
MCM5 | REACTOME; |
in same component |
MCM6 | REACTOME; |
in same component |
MCM7 | REACTOME; |
in same component |
MNAT1 | REACTOME; |
in same component |
MSH4 | REACTOME; |
in same component |
MSH5 | REACTOME; |
in same component |
ORC1 | REACTOME; |
in same component |
ORC2 | REACTOME; |
in same component |
ORC3 | REACTOME; |
in same component |
ORC4 | REACTOME; |
in same component |
ORC5 | REACTOME; |
in same component |
ORC6 | REACTOME; |
in same component |
PCNA | REACTOME; |
in same component |
POLA1 | REACTOME; |
in same component |
POLA2 | REACTOME; |
in same component |
POLD1 | REACTOME; |
in same component |
POLD2 | REACTOME; |
in same component |
POLD3 | REACTOME; |
in same component |
POLD4 | REACTOME; |
in same component |
PRIM1 | REACTOME; |
in same component |
PRIM2 | REACTOME; |
in same component |
RAD17 | NCI_NATURE; |
in same component |
RAD1 | NCI_NATURE; |
in same component |
RAD1 | REACTOME; |
in same component |
RAD23B | REACTOME; |
in same component |
RAD51 | REACTOME; |
in same component |
RAD52 | REACTOME; |
in same component |
RAD9A | NCI_NATURE; |
in same component |
RFC2 | NCI_NATURE; |
in same component |
RFC2 | REACTOME; |
in same component |
RFC3 | NCI_NATURE; |
in same component |
RFC3 | REACTOME; |
in same component |
RFC4 | NCI_NATURE; |
in same component |
RFC4 | REACTOME; |
in same component |
RFC5 | NCI_NATURE; |
in same component |
RFC5 | REACTOME; |
in same component |
RPA2 | NCI_NATURE; |
in same component |
RPA2 | REACTOME; |
in same component |
RPA3 | REACTOME; |
in same component |
RPA4 | REACTOME; |
in same component |
SMARCAL1 | NCI_NATURE; |
in same component |
TIMELESS | NCI_NATURE; |
in same component |
TIPIN | NCI_NATURE; |
in same component |
TOP3A | REACTOME; |
in same component |
TOPBP1 | NCI_NATURE; |
in same component |
XPA | REACTOME; |
in same component |
XPC | REACTOME; |
interacts with |
ACTB | INTACT; |
interacts with |
AICDA | HPRD; |
interacts with |
AKTIP | BIOGRID; |
interacts with |
AKTIP | HPRD; |
interacts with |
AKTIP | MINT; |
interacts with |
APLF | MINT; |
interacts with |
ASCC2 | BIOGRID; |
interacts with |
ASCC2 | HPRD; |
interacts with |
ASCC2 | MINT; |
interacts with |
ATG101 | BIOGRID; |
interacts with |
ATRIP | BIOGRID; |
interacts with |
ATR | BIOGRID; |
interacts with |
BLM | BIOGRID; |
interacts with |
BLM | HPRD; |
interacts with |
BRCA1 | BIOGRID; |
interacts with |
BRCA2 | BIOGRID; |
interacts with |
BRCA2 | HPRD; |
interacts with |
BRIP1 | BIOGRID; |
interacts with |
CCNA2 | BIOGRID; |
interacts with |
CDK4 | HPRD; |
interacts with |
CDKN1A | HPRD; |
interacts with |
CHAF1A | BIOGRID; |
interacts with |
CHD1L | BIOGRID; |
interacts with |
CPE | BIOGRID; |
interacts with |
CPE | HPRD; |
interacts with |
CPE | MINT; |
interacts with |
DHX9 | HPRD; |
interacts with |
DMC1 | HPRD; |
interacts with |
FAM203A | BIOGRID; |
interacts with |
FAM203A | HPRD; |
interacts with |
FAM203A | MINT; |
interacts with |
FANCA | BIOGRID; |
interacts with |
FANCG | BIOGRID; |
interacts with |
FANCM | BIOGRID; |
interacts with |
FYCO1 | BIOGRID; |
interacts with |
HELB | HPRD; |
interacts with |
HNRNPUL1 | BIOGRID; |
interacts with |
HUS1 | BIOGRID; |
interacts with |
HUS1 | HPRD; |
interacts with |
KIN | BIOGRID; |
interacts with |
KIN | HPRD; |
interacts with |
LIG3 | MINT; |
interacts with |
MCM2 | BIOGRID; |
interacts with |
MCM2 | HPRD; |
interacts with |
MCM4 | BIOGRID; |
interacts with |
MCM6 | BIOGRID; |
interacts with |
MCM7 | BIOGRID; |
interacts with |
MCPH1 | BIOGRID; |
interacts with |
MSH4 | BIOGRID; |
interacts with |
MSH4 | HPRD; |
interacts with |
MUTYH | BIOGRID; |
interacts with |
MUTYH | HPRD; |
interacts with |
ORC2 | BIOGRID; |
interacts with |
ORC2 | HPRD; |
interacts with |
ORC6 | BIOGRID; |
interacts with |
PARP1 | MINT; |
interacts with |
PCNA | BIOGRID; |
interacts with |
PCNA | HPRD; |
interacts with |
POLA1 | MINT; |
interacts with |
POLL | HPRD; |
interacts with |
PRIM1 | BIOGRID; |
interacts with |
PRIM2 | MINT; |
interacts with |
PRKDC | BIOGRID; |
interacts with |
PRKDC | HPRD; |
interacts with |
PRKDC | MINT; |
interacts with |
RAD1 | BIOGRID; |
interacts with |
RAD1 | HPRD; |
interacts with |
RAD51 | BIOGRID; |
interacts with |
RAD51 | HPRD; |
interacts with |
RAD51 | INTACT; |
interacts with |
RAD52 | BIOGRID; |
interacts with |
RAD9A | BIOGRID; |
interacts with |
RAD9A | HPRD; |
interacts with |
RB1CC1 | BIOGRID; |
interacts with |
RBM23 | BIOGRID; |
interacts with |
RBM23 | HPRD; |
interacts with |
RBM23 | MINT; |
interacts with |
RECQL | HPRD; |
interacts with |
RECQL | MINT; |
interacts with |
RMI1 | HPRD; |
interacts with |
RPA2 | BIOGRID; |
interacts with |
RPA2 | HPRD; |
interacts with |
RPA3 | BIOGRID; |
interacts with |
RPA3 | HPRD; |
interacts with |
RPA3 | INTACT; |
interacts with |
RPA4 | BIOGRID; |
interacts with |
RPA4 | HPRD; |
interacts with |
SELENBP1 | BIOGRID; |
interacts with |
SELENBP1 | HPRD; |
interacts with |
SELENBP1 | MINT; |
interacts with |
SMARCA4 | BIOGRID; |
interacts with |
TCEA2 | BIOGRID; |
interacts with |
TIPIN | BIOGRID; |
interacts with |
TOP1 | HPRD; |
interacts with |
TOP1 | MINT; |
interacts with |
TOP3A | BIOGRID; |
interacts with |
TOP3A | HPRD; |
interacts with |
TOPBP1 | BIOGRID; |
interacts with |
TP53BP1 | BIOGRID; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TREX1 | HPRD; |
interacts with |
WRN | HPRD; |
interacts with |
XPA | BIOGRID; |
interacts with |
XPA | HPRD; |
interacts with |
XRCC1 | MINT; |
interacts with |
XRCC5 | MINT; |
interacts with |
XRCC6 | MINT; |
Metabolic Interaction [Top] | ||
There is no record for RPA1 |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ATM | REACTOME; |
reacts with |
ATRIP | NCI_NATURE; |
reacts with |
ATRIP | REACTOME; |
reacts with |
ATR | NCI_NATURE; |
reacts with |
BLM | REACTOME; |
reacts with |
BRCA1 | REACTOME; |
reacts with |
BRCA2 | REACTOME; |
reacts with |
CCNH | REACTOME; |
reacts with |
CDC45 | REACTOME; |
reacts with |
CDC6 | NCI_NATURE; |
reacts with |
CDC6 | REACTOME; |
reacts with |
CDC7 | REACTOME; |
reacts with |
CDK2 | REACTOME; |
reacts with |
CDK4 | REACTOME; |
reacts with |
CDK7 | REACTOME; |
reacts with |
CEP164 | NCI_NATURE; |
reacts with |
CHEK1 | NCI_NATURE; |
reacts with |
CLSPN | NCI_NATURE; |
reacts with |
DBF4 | REACTOME; |
reacts with |
DDB1 | REACTOME; |
reacts with |
DDB2 | REACTOME; |
reacts with |
DMC1 | REACTOME; |
reacts with |
DNA2 | REACTOME; |
reacts with |
ERCC1 | REACTOME; |
reacts with |
ERCC2 | REACTOME; |
reacts with |
ERCC3 | REACTOME; |
reacts with |
ERCC4 | REACTOME; |
reacts with |
ERCC5 | REACTOME; |
reacts with |
GTF2H1 | REACTOME; |
reacts with |
GTF2H2 | REACTOME; |
reacts with |
GTF2H3 | REACTOME; |
reacts with |
GTF2H4 | REACTOME; |
reacts with |
H2AFX | REACTOME; |
reacts with |
HIST3H3 | REACTOME; |
reacts with |
HUS1 | NCI_NATURE; |
reacts with |
HUS1 | REACTOME; |
reacts with |
MCM10 | REACTOME; |
reacts with |
MCM2 | REACTOME; |
reacts with |
MCM3 | REACTOME; |
reacts with |
MCM4 | REACTOME; |
reacts with |
MCM5 | REACTOME; |
reacts with |
MCM6 | REACTOME; |
reacts with |
MCM7 | REACTOME; |
reacts with |
MLH1 | REACTOME; |
reacts with |
MLH3 | REACTOME; |
reacts with |
MNAT1 | REACTOME; |
reacts with |
MSH4 | REACTOME; |
reacts with |
MSH5 | REACTOME; |
reacts with |
ORC1 | REACTOME; |
reacts with |
ORC2 | REACTOME; |
reacts with |
ORC3 | REACTOME; |
reacts with |
ORC4 | REACTOME; |
reacts with |
ORC5 | REACTOME; |
reacts with |
ORC6 | REACTOME; |
reacts with |
PCNA | REACTOME; |
reacts with |
POLA1 | REACTOME; |
reacts with |
POLA2 | REACTOME; |
reacts with |
POLD1 | REACTOME; |
reacts with |
POLD2 | REACTOME; |
reacts with |
POLD3 | REACTOME; |
reacts with |
POLD4 | REACTOME; |
reacts with |
POLE2 | REACTOME; |
reacts with |
POLE | REACTOME; |
reacts with |
PRIM1 | REACTOME; |
reacts with |
PRIM2 | REACTOME; |
reacts with |
RAD17 | NCI_NATURE; |
reacts with |
RAD1 | NCI_NATURE; |
reacts with |
RAD1 | REACTOME; |
reacts with |
RAD23B | REACTOME; |
reacts with |
RAD51 | REACTOME; |
reacts with |
RAD52 | REACTOME; |
reacts with |
RAD9A | NCI_NATURE; |
reacts with |
RFC1 | REACTOME; |
reacts with |
RFC2 | NCI_NATURE; |
reacts with |
RFC2 | REACTOME; |
reacts with |
RFC3 | NCI_NATURE; |
reacts with |
RFC3 | REACTOME; |
reacts with |
RFC4 | NCI_NATURE; |
reacts with |
RFC4 | REACTOME; |
reacts with |
RFC5 | NCI_NATURE; |
reacts with |
RFC5 | REACTOME; |
reacts with |
RPA1 | NCI_NATURE; |
reacts with |
RPA1 | REACTOME; |
reacts with |
RPA2 | NCI_NATURE; |
reacts with |
RPA2 | REACTOME; |
reacts with |
RPA3 | REACTOME; |
reacts with |
RPA4 | REACTOME; |
reacts with |
SMARCAL1 | NCI_NATURE; |
reacts with |
TIMELESS | NCI_NATURE; |
reacts with |
TIPIN | NCI_NATURE; |
reacts with |
TOP3A | REACTOME; |
reacts with |
TOPBP1 | NCI_NATURE; |
reacts with |
XPA | REACTOME; |
reacts with |
XPC | REACTOME; |
state change |
ATM | REACTOME; |
state change |
BRCA1 | REACTOME; |
state change |
BRCA2 | REACTOME; |
state change |
CCNH | REACTOME; |
state change |
CDK4 | REACTOME; |
state change |
CDK7 | REACTOME; |
state change |
DDB1 | REACTOME; |
state change |
DDB2 | REACTOME; |
state change |
DMC1 | REACTOME; |
state change |
ERCC1 | REACTOME; |
state change |
ERCC2 | REACTOME; |
state change |
ERCC3 | REACTOME; |
state change |
ERCC4 | REACTOME; |
state change |
ERCC5 | REACTOME; |
state change |
GTF2H1 | REACTOME; |
state change |
GTF2H2 | REACTOME; |
state change |
GTF2H3 | REACTOME; |
state change |
GTF2H4 | REACTOME; |
state change |
H2AFX | REACTOME; |
state change |
HIST3H3 | REACTOME; |
state change |
MNAT1 | REACTOME; |
state change |
MND1 | REACTOME; |
state change |
PSMC3IP | REACTOME; |
state change |
RAD23B | REACTOME; |
state change |
RAD51C | REACTOME; |
state change |
RAD51 | REACTOME; |
state change |
RFC2 | REACTOME; |
state change |
RFC3 | REACTOME; |
state change |
RFC4 | REACTOME; |
state change |
RFC5 | REACTOME; |
state change |
RPA1 | REACTOME; |
state change |
RPA2 | REACTOME; |
state change |
RPA3 | REACTOME; |
state change |
TEX15 | REACTOME; |
state change |
XPA | REACTOME; |
state change |
XPC | REACTOME; |
state change |
YWHAZ | NCI_NATURE; |