| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 6196 |
Name | RPS6KA2 |
Synonym | HU-2|MAPKAPK1C|RSK|RSK3|S6K-alpha|S6K-alpha2|p90-RSK3|pp90RSK3;ribosomal protein S6 kinase, 90kDa, polypeptide 2;RPS6KA2;ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
Definition | 90 kDa ribosomal protein S6 kinase 2|MAP kinase-activated protein kinase 1c|MAPK-activated protein kinase 1c|MAPKAP kinase 1c|MAPKAPK-1c|RSK-3|S6K-alpha-2|p90-RSK 2|p90RSK2|ribosomal S6 kinase 3|ribosomal protein S6 kinase 90kDa polypeptide 2|ribosomal pr |
Position | 6q27 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 14369 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | mTOR signaling pathway;KEGG PATHWAY;hsa04150 |
Pathway | Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade;PANTHER;P00032 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Ras Pathway;PANTHER;P04393 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 6196 |
Links to all GeneRIF Items | 6196 |
Links to iHOP | 6196 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>6196 : length: 2226 atgccaatcgcacagttgctggaactatggaaaaagatcgaggtggagcctatggaaata gagaccacagaggaggatctcaacctggatgtggagcccaccacagaagacactgcagaa gaagaagaaggcgtcgtgaaggagatagacatcagccatcatgtgaaggagggctttgag aaggcagatccttcccagtttgagctgctgaaggttttaggacaaggatcctatggaaag gtgttcctggtgaggaaggtgaaggggtccgacgctgggcagctctacgccatgaaggtc cttaagaaagccaccctaaaagttcgggaccgagtgagatcgaagatggagagagacatc ttggcagaagtgaatcaccccttcattgtgaagcttcattatgcctttcagacggaagga aagctctacctgatcctggacttcctgcggggaggggacctcttcacccggctctccaaa gaggtcatgttcacggaggaggatgtcaagttctacctggctgagctggccttggcttta gaccatctccacagcctggggatcatctacagagatctgaagcctgagaacatcctcctg gatgaagaggggcacattaagatcacagatttcggcctgagtaaggaggccattgaccac gacaagagagcgtactccttctgcgggacgatcgagtacatggcgcccgaggtggtgaac cggcgaggacacacgcagagtgccgactggtggtccttcggcgtgctcatgtttgagatg ctcacggggtccctgccgttccaggggaaggacaggaaggagaccatggctctcatcctc aaagccaagctggggatgccgcagttcctcagtggggaggcacagagtttgctgcgagct ctcttcaaacggaacccctgcaaccggctgggtgctggcattgacggagtggaggaaatt aagcgccatcccttctttgtgaccatagactggaacacgctgtaccggaaggagatcaag ccaccgttcaaaccagcagtgggcaggcctgaggacaccttccactttgaccccgagttc acagcgcggacgcccacagactctcctggcgtccccccgagtgcaaacgctcatcacctg tttagaggattcagctttgtggcctcaagcctgatccaggagccctcacagcaagatctg cacaaagtcccagttcacccaatcgtgcagcagttacacgggaacaacatccacttcacc gatggctacgagatcaaggaggacatcggggtgggctcctactcagtgtgcaagcgatgt gtgcataaagccacagacaccgagtatgccgtgaagatcattgataagagcaagagagac ccctcggaagagattgagatcctcctgcggtacggccagcacccgaacatcatcaccctc aaggatgtctatgatgatggcaagtttgtgtacctggtaatggagctgatgcgtggtggg gagctcctggaccgcatcctccggcagagatacttctcggagcgcgaagccagtgacgtc ctgtgcaccatcaccaagaccatggactacctccattcccagggggttgttcatcgagac ctgaagccgagtaacatcctgtacagggatgagtcggggagcccagaatccatccgagtc tgcgacttcggctttgccaagcagctgcgcgcggggaacgggctgctcatgacaccctgc tacacggccaatttcgtggccccggaggtcctgaagcgtcaaggctatgatgcggcgtgt gacatctggagtttggggatcctgttgtacaccatgctggcaggatttaccccttttgca aatgggccagacgatacccctgaggagattctggcgcggatcggcagtgggaagtatgcc ctttctgggggaaactgggactcgatatctgacgcagctaaagacgtcgtgtccaagatg ctccacgtggaccctcatcagcgcctgacggcgatgcaagtgctcaaacacccgtgggtg gtcaacagagagtacctgtccccaaaccagctcagccgacaggacgtgcacctggtgaag ggcgcgatggccgccacctactttgctctaaacagaacacctcaggccccgcggctggag cccgtgctgtcatccaacctggctcagcgcagaggcatgaagagactcacgtccacgcgg ctgtag |
Protein Sequence |
>6196 : length: 741 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVEPTTEDTAEEEEGVVKEIDISHHVKEGFE KADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDI LAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAL DHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVN RRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRA LFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEF TARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFT DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITL KDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRD LKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAAC DIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKM LHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLE PVLSSNLAQRRGMKRLTSTRL |