| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 64326 |
Name | RFWD2 |
Synonym | COP1|RNF200;ring finger and WD repeat domain 2, E3 ubiquitin protein ligase;RFWD2;ring finger and WD repeat domain 2, E3 ubiquitin protein ligase |
Definition | E3 ubiquitin-protein ligase RFWD2|RING finger protein 200|constitutive photomorphogenesis protein 1 homolog|putative ubiquitin ligase COP1 |
Position | 1q25.1-q25.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 14021 |
TUSON P-value | 1 |
|
Pathways and Diseases |
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Pathway | Autodegradation of the E3 ubiquitin ligase COP1;PID Reactome;500317 |
Pathway | p53 pathway;PID Curated;200175 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | P53 pathway feedback loops 1;PANTHER;P04392 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 64326 |
Links to all GeneRIF Items | 64326 |
Links to iHOP | 64326 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>64326 : length: 2124 atgtctggtagccgccaggccgggtcgggctccgctgggacaagccccgggtcctcggcg gcctcctcggtgacttccgcctcctcgtctttatcctcttccccgtcgccgccttccgtg gcggtttcggcggcagcgctggtgtccggcggggtggcccaggccgccggctcgggcggc ctcgggggcccggtgcggcctgtgttggtggcgcccgccgtatcgggtagcggcggcggg gcggtgtccacgggcctgtcccggcacagctgcgcggccaggcccagcgccggcgtagga ggcagcagctccagcctaggcagcggcagcaggaagcgacctctcctcgcccccctctgc aacgggctcatcaactcctacgaggacaaaagcaacgacttcgtatgccccatctgcttt gatatgattgaagaagcatacatgacaaaatgtggccacagcttttgctacaagtgtatt catcagagtttggaggacaataatagatgtcccaagtgtaactatgttgtggacaatatt gaccatctgtatcctaatttcttggtgaatgaactcattcttaaacagaagcaaagattt gaggaaaagaggttcaaattggaccactcaaatggccacaggtggcagatatttcaagat tggttgggaactgaccaagataaccttgatttggccaatgtcaatcttatgttggagtta ctagtgcagaagaagaaacaactggaagcagaatcacatgcagcccaactacagattctt atggaattcctcaaggttgcaagaagaaataagagagaggaaatgagtggcttatactct cctgtcagtgaggatagcacagtgcctcaatttgaagctccttctccatcacacagtagt attattgattccacagaatacagccaacctccaggtttcagtggcagttctcagacaaag aaacagccttggtataatagcacgttagcatcaagacgaaaacgacttactgctcatttt gaagacttggagcagtgttacttttctacaaggatgtctcgtatctcagatgacagtcga actgcaagccagttggatgaatttcaggaatgcttgtccaagtttactcgatataattca gtacgacctttagccacattgtcatatgctagtgatctctataatggttccagtatagtc tctagtattgaatttgaccgggattgtgactattttgcgattgctggagttacaaagaag attaaagtctatgaatatgacactgtcatccaggatgcagtggatattcattaccctgag aatgaaatgacctgcaattcgaaaatcagctgtatcagttggagtagttaccataagaac ctgttagctagcagtgattatgaaggcactgttattttatgggatggattcacaggacag aggtcaaaggtctatcaggagcatgagaagaggtgttggagtgttgactttaatttgatg gatcctaaactcttggcttcaggttctgatgatgcaaaagtgaagctgtggtctaccaat ctagacaactcagtggcaagcattgaggcaaaggctaatgtgtgctgtgttaaattcagc ccctcttccagataccatttggctttcggctgtgcagatcactgtgtccactactatgat cttcgtaacactaaacagccaatcatggtattcaaaggacaccgtaaagcagtctcttat gcaaagtttgtgagtggtgaggaaattgtctctgcctcaacagacagtcagctaaaactg tggaatgtagggaaaccatactgcctacgttccttcaagggtcatatcaatgaaaaaaac tttgtaggcctggcttccaatggagattatatagcttgtggaagtgaaaataactctctc tacctgtactataaaggactttctaagactttgctaacttttaagtttgatacagtcaaa agtgttctcgacaaagaccgaaaagaagatgatacaaatgaatttgttagtgctgtgtgc tggagggcactaccagatggggagtccaatgtgctgattgctgctaacagtcagggtaca attaaggtgctagaattggtatga |
Protein Sequence |
>64326 : length: 707 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI DHLYPNFLVNELILKQKQRFEEKRFKLDHSNGHRWQIFQDWLGTDQDNLDLANVNLMLEL LVQKKKQLEAESHAAQLQILMEFLKVARRNKREEMSGLYSPVSEDSTVPQFEAPSPSHSS IIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSR TASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKK IKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQ RSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFS PSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKL WNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVK SVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELV |