Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6498

Name

SKIL

Synonym

SNO|SnoA|SnoI|SnoN;SKI-like proto-oncogene;SKIL;SKI-like proto-oncogene

Definition

SKI-like oncogene|ski-like protein|ski-related oncogene snoN

Position

3q26

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

14981

TUSON P-value

1

   Caution

This gene might be oncogene according to our integrated oncogene list.

Pathways and Diseases

Pathway

TGF-beta receptor signaling;PID Curated;200195

Pathway

TGF-beta signaling pathway;PANTHER;P00052

Pathway

tgf beta signaling pathway;PID BioCarta;100017

Pathway

Regulation of nuclear SMAD2/3 signaling;PID Curated;200002

Disease

Scleroderma;FunDO

Disease

Barrett's esophagus;FunDO

Disease

Melanoma;FunDO

Disease

Systemic scleroderma;FunDO

External Links

Links to Entrez Gene

6498

Links to all GeneRIF Items

6498

Links to iHOP

6498

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>6498 : length: 1917
atggaaaacctccagacaaatttctccttggttcagggctcaactaaaaaactgaatggg
atgggagatgatggcagccccccagcgaaaaaaatgataacggacattcatgcaaatgga
aaaacgataaacaaggtgccaacagttaagaaggaacacttggatgactatggagaagca
ccagtggaaactgatggagagcatgttaagcgaacctgtacttctgttcctgaaactttg
catttaaatcccagtttgaaacacacattggcacaattccatttaagtagtcagagctcg
ctgggtggaccagcagcattttctgctcggcattcccaagaaagcatgtcgcctactgta
tttctgcctcttccatcacctcaggttcttcctggcccattgctcatcccttcagatagc
tccacagaactcactcagactgtgttggaaggggaatctatttcttgttttcaagttgga
ggagaaaagagactctgtttgccccaagtcttaaattctgttctccgagaatttacactc
cagcaaataaatacagtgtgtgatgaactgtacatatattgttcaaggtgtacttcagac
cagcttcatatcttaaaggtactgggcatacttccattcaatgccccatcctgtgggctg
attacattaactgatgcacaaagattatgtaatgctttattgcggccacgaacttttcct
caaaatggtagcgtacttcctgctaaaagctcattggcccagttaaaggaaactggcagt
gcctttgaagtggagcatgaatgcctaggcaaatgtcagggtttatttgcaccccagttt
tatgttcagcctgatgctccgtgtattcaatgtctggagtgttgtggaatgtttgcaccc
cagacgtttgtgatgcattctcacagatcacctgacaaaagaacttgccactggggcttt
gaatcagctaaatggcattgctatcttcatgtgaaccaaaaatacttaggaacacctgaa
gaaaagaaactgaagataattttagaagaaatgaaggagaagtttagcatgagaagtgga
aagagaaatcaatccaagacagatgcaccatcaggaatggaattacagtcatggtatcct
gttataaagcaggaaggtgaccatgtttctcagacacattcatttttacaccccagctac
tacttatacatgtgtgataaagtggttgccccaaatgtgtcacttacttctgctgtatcc
cagtctaaagagctcacaaagacagaggcaaatgcatcaatctcaaataattctacaagt
aaaaggaaatctgagtctgccacttgcaacttagtcagagacataaacaaagtgggaatt
ggccttgttgctgccgcttcatctccgcttcttgtgaaagatgtcatttgtgaggatgat
aagggaaaaatcatggaagaagtaatgagaacttatttaaaacaacaggaaaaactaaac
ttgattttgcaaaagaagcaacaacttcagatggaagtaaaaatgttgagtagttcaaaa
tctatgaaggaactcactgaagaacagcagaatttacagaaagagcttgaatctttgcag
aatgaacatgctcaaagaatggaagaattttatgttgaacagaaagacttagagaaaaaa
ttggagcagataatgaagcaaaaatgtacctgtgactcaaatttagaaaaagacaaagag
gctgaatatgcaggacagttggcagaactgaggcagagattggaccatgctgaggccgat
aggcaagaactccaagatgaactcagacaggaacgggaagcaagacagaagttagagatg
atgataaaagagctaaagctgcaaattctgaaatcatcaaagactgctaaagaatag

Protein Sequence

>6498 : length: 638
MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA
PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
QSKELTKTEANASISNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDD
KGKIMEEVMRTYLKQQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQ
NEHAQRMEEFYVEQKDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEAD
RQELQDELRQEREARQKLEMMIKELKLQILKSSKTAKE



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