Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6498

Name

SKIL

Synonymous

SNO|SnoA|SnoI|SnoN;SKI-like proto-oncogene;SKIL;SKI-like proto-oncogene

Definition

SKI-like oncogene|ski-like protein|ski-related oncogene snoN

Position

3q26

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

SnoN(h) + sumo1(h) --> SnoN(h){sumo} (sumoylation)
SKIL(h) --> SnoN(h) (expression).
SnoN(h) --26S proteasome(h)--> protein remnants (degradation)
SnoN(h) + 3 ubiquitin(h) --> SnoN(h){ubK440}{ubK446}{ubK449} (ubiquitination)
Smad3(m.s.) + SnoN(h) <==> Smad3(m.s.):SnoN(h) (binding)
Smad2(m.s.) + SnoN(h) <==> Smad2(m.s.):SnoN(h) (binding)
SnoN(h) + Fzr1(m.s.) <==> SnoN(h):Fzr1(m.s.) (binding)
Cdc16(h) + SnoN(h) <==> Cdc16(h):SnoN(h) (binding)
Cdc27(h) + SnoN(h) <==> Cdc27(h):SnoN(h) (binding)
SnoN(h) + n ubiquitin(m.s.) --ATP,E1(m.s.),Ubc5A(m.s.),Ubc5B(m.s.)--> SnoN(h){ub(n)} (ubiquitination)
SKIL(h) --> SnoN(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for SKIL

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 171556710 - 171558710Agilent_014791

chr3

Promoter: 171556710 - 171558710GSE27584

chr3

Promoter: 171556710 - 171558710Agilent_014791_44K


')