| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 6772 |
Name | STAT1 |
Synonym | CANDF7|IMD31A|IMD31B|IMD31C|ISGF-3|STAT91;signal transducer and activator of transcription 1, 91kDa;STAT1;signal transducer and activator of transcription 1, 91kDa |
Definition | signal transducer and activator of transcription 1, 91kD|signal transducer and activator of transcription 1-alpha/beta|signal transducer and activator of transcription-1|transcription factor ISGF-3 components p91/p84 |
Position | 2q32.2 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 15873 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Signaling events mediated by TCPTP;PID Curated;200065 |
Pathway | ifn gamma signaling pathway;PID BioCarta;100138 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | IL23-mediated signaling events;PID Curated;200131 |
Pathway | Interferon-gamma signaling pathway;PANTHER;P00035 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | pdgf signaling pathway;PID BioCarta;100077 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | Pancreatic cancer;KEGG PATHWAY;hsa05212 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | TNF receptor signaling pathway;PID Curated;200086 |
Pathway | mapkinase signaling pathway;PID BioCarta;100113 |
Pathway | EPO signaling pathway;PID Curated;200157 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | egf signaling pathway;PID BioCarta;100181 |
Pathway | EGF receptor (ErbB1) signaling pathway;PID Curated;200085 |
Pathway | PDGFR-beta signaling pathway;PID Curated;200127 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | IL2-mediated signaling events;PID Curated;200082 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | ifn alpha signaling pathway;PID BioCarta;100139 |
Pathway | IFN-gamma pathway;PID Curated;200110 |
Pathway | inhibition of cellular proliferation by gleevec;PID BioCarta;100154 |
Pathway | bioactive peptide induced signaling pathway;PID BioCarta;100226 |
Pathway | p38 mapk signaling pathway;PID BioCarta;100085 |
Pathway | JAK/STAT signaling pathway;PANTHER;P00038 |
Pathway | Leishmaniasis;KEGG PATHWAY;hsa05140 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | tpo signaling pathway;PID BioCarta;100012 |
Pathway | il22 soluble receptor signaling pathway;PID BioCarta;100131 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Oxidative stress response;PANTHER;P00046 |
Pathway | IL6-mediated signaling events;PID Curated;200124 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | IL27-mediated signaling events;PID Curated;200023 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Signaling events mediated by Stem cell factor receptor (c-Kit);PID Curated;200156 |
Pathway | GMCSF-mediated signaling events;PID Curated;200015 |
Pathway | FGF signaling pathway;PID Curated;200189 |
Disease | Mycobacterial infection, atypical, familial disseminated;OMIM |
Disease | STAT1 deficiency, complete;OMIM |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Immune system diseases;KEGG DISEASE |
Disease | IFN-gamma/IL-12 axis;KEGG DISEASE;H00089 |
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External Links |
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Links to Entrez Gene | 6772 |
Links to all GeneRIF Items | 6772 |
Links to iHOP | 6772 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>6772 : length: 2253 atgtctcagtggtacgaacttcagcagcttgactcaaaattcctggagcaggttcaccag ctttatgatgacagttttcccatggaaatcagacagtacctggcacagtggttagaaaag caagactgggagcacgctgccaatgatgtttcatttgccaccatccgttttcatgacctc ctgtcacagctggatgatcaatatagtcgcttttctttggagaataacttcttgctacag cataacataaggaaaagcaagcgtaatcttcaggataattttcaggaagacccaatccag atgtctatgatcatttacagctgtctgaaggaagaaaggaaaattctggaaaacgcccag agatttaatcaggctcagtcggggaatattcagagcacagtgatgttagacaaacagaaa gagcttgacagtaaagtcagaaatgtgaaggacaaggttatgtgtatagagcatgaaatc aagagcctggaagatttacaagatgaatatgacttcaaatgcaaaaccttgcagaacaga gaacacgagaccaatggtgtggcaaagagtgatcagaaacaagaacagctgttactcaag aagatgtatttaatgcttgacaataagagaaaggaagtagttcacaaaataatagagttg ctgaatgtcactgaacttacccagaatgccctgattaatgatgaactagtggagtggaag cggagacagcagagcgcctgtattggggggccgcccaatgcttgcttggatcagctgcag aactggttcactatagttgcggagagtctgcagcaagttcggcagcagcttaaaaagttg gaggaattggaacagaaatacacctacgaacatgaccctatcacaaaaaacaaacaagtg ttatgggaccgcaccttcagtcttttccagcagctcattcagagctcgtttgtggtggaa agacagccctgcatgccaacgcaccctcagaggccgctggtcttgaagacaggggtccag ttcactgtgaagttgagactgttggtgaaattgcaagagctgaattataatttgaaagtc aaagtcttatttgataaagatgtgaatgagagaaatacagtaaaaggatttaggaagttc aacattttgggcacgcacacaaaagtgatgaacatggaggagtccaccaatggcagtctg gcggctgaatttcggcacctgcaattgaaagaacagaaaaatgctggcaccagaacgaat gagggtcctctcatcgttactgaagagcttcactcccttagttttgaaacccaattgtgc cagcctggtttggtaattgacctcgagacgacctctctgcccgttgtggtgatctccaac gtcagccagctcccgagcggttgggcctccatcctttggtacaacatgctggtggcggaa cccaggaatctgtccttcttcctgactccaccatgtgcacgatgggctcagctttcagaa gtgctgagttggcagttttcttctgtcaccaaaagaggtctcaatgtggaccagctgaac atgttgggagagaagcttcttggtcctaacgccagccccgatggtctcattccgtggacg aggttttgtaaggaaaatataaatgataaaaattttcccttctggctttggattgaaagc atcctagaactcattaaaaaacacctgctccctctctggaatgatgggtgcatcatgggc ttcatcagcaaggagcgagagcgtgccctgttgaaggaccagcagccggggaccttcctg ctgcggttcagtgagagctcccgggaaggggccatcacattcacatgggtggagcggtcc cagaacggaggcgaacctgacttccatgcggttgaaccctacacgaagaaagaactttct gctgttactttccctgacatcattcgcaattacaaagtcatggctgctgagaatattcct gagaatcccctgaagtatctgtatccaaatattgacaaagaccatgcctttggaaagtat tactccaggccaaaggaagcaccagagccaatggaacttgatggccctaaaggaactgga tatatcaagactgagttgatttctgtgtctgaagttcacccttctagacttcagaccaca gacaacctgctccccatgtctcctgaggagtttgacgaggtgtctcggatagtgggctct gtagaattcgacagtatgatgaacacagtatag |
Protein Sequence |
>6772 : length: 750 MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDL LSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQ RFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNR EHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWK RRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQV LWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKV KVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTN EGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAE PRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWT RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL LRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIP ENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTT DNLLPMSPEEFDEVSRIVGSVEFDSMMNTV |