| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6929 |
Name | TCF3 |
Synonym | E2A|E47|ITF1|TCF-3|VDIR|bHLHb21;transcription factor 3;TCF3;transcription factor 3 |
Definition | VDR interacting repressor|class B basic helix-loop-helix protein 21|helix-loop-helix protein HE47|immunoglobulin transcription factor 1|kappa-E2-binding factor|negative vitamin D response element-binding protein|transcription factor 3 (E2A immunoglobulin |
Position | 19p13.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 16274 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
|
Pathways and Diseases |
|
Pathway | Notch-mediated HES/HEY network;PID Curated;200196 |
Pathway | p38 signaling mediated by MAPKAP kinases;PID Curated;200135 |
Pathway | Myogenesis;Reactome;REACT:21303 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Disease | Leukemia, acute lymphoblastic;OMIM |
Disease | Acute lymphoblastic leukemia (ALL) (Precursor B lymphoblastic leukemia);KEGG DISEASE;H00001 |
Disease | Cancers;KEGG DISEASE |
Disease | Cancers of haematopoietic and lymphoid tissues;KEGG DISEASE |
|
External Links |
|
Links to Entrez Gene | 6929 |
Links to all GeneRIF Items | 6929 |
Links to iHOP | 6929 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>6929 : length: 1956 atgaaccagccgcagaggatggcgcctgtgggcacagacaaggagctcagtgacctcctg gacttcagcatgatgttcccgctgcctgtcaccaacgggaagggccggcccgcctccctg gccggggcgcagttcggaggttcaggtcttgaggaccggcccagctcaggctcctggggc agcggcgaccagagcagctcctcctttgaccccagccggaccttcagcgagggcacccac ttcactgagtcgcacagcagcctctcttcatccacattcctgggaccgggactcggaggc aagagcggtgagcggggcgcctatgcctccttcgggagagacgcaggcgtgggcggcctg actcaggctggcttcctgtcaggcgagctggccctcaacagccccgggcccctgtcccct tcgggcatgaaggggacctcccagtactacccctcctactccggcagctcccggcggaga gcggcagacggcagcctagacacgcagcccaagaaggtccggaaggtcccgccgggtctt ccatcctcggtgtacccacccagctcaggtgaggactacggcagggatgccaccgcctac ccgtccgccaagacccccagcagcacctatcccgcccccttctacgtggcagatggcagc ctgcacccctcagccgagctctggagtcccccgggccaggcgggcttcgggcccatgctg ggtgggggctcatccccgctgcccctcccgcccggtagcggcccggtgggcagcagtgga agcagcagcacgtttggtggcctgcaccagcacgagcgtatgggctaccagctgcatgga gcagaggtgaacggtgggctcccatctgcatcctccttctcctcagcccccggagccacg tacggcggcgtctccagccacacgccgcctgtcagcggggccgacagcctcctgggctcc cgagggaccacagctggcagctccggggatgccctcggcaaagcactggcctcgatctac tccccggatcactcaagcaataacttctcgtccagcccttctacccccgtgggctccccc cagggcctggcaggaacgtcacagtggcctcgagcaggagcccccggtgccttatcgccc agctacgacgggggtctccacggcctgcagagtaagatagaagaccacctggacgaggcc atccacgtgctccgcagccacgccgtgggcacagccggcgacatgcacacgctgctgcct ggccacggggcgctggcctcaggtttcaccggccccatgtcactgggcgggcggcacgca ggcctggttggaggcagccaccccgaggacggcctcgcaggcagcaccagcctcatgcac aaccacgcggccctccccagccagccaggcaccctccctgacctgtctcggcctcccgac tcctacagtgggctagggcgagcaggtgccacggcggccgccagcgagatcaagcgggag gagaaggaggacgaggagaacacgtcagcggctgaccactcggaggaggagaagaaggag ctgaaggccccccgggcccggaccagcagtacggacgaggtgctgtccctggaggagaaa gacctgagggaccgggagaggcgcatggccaataacgcgcgggagcgggtgcgcgtgcgg gatattaacgaggccttccgggagctggggcgcatgtgccagatgcacctcaagtcggac aaagcgcagaccaagctgctcatcctgcagcaggccgtgcaggtcatcctggggctggag cagcaggtgcgagagcggaacctgaatcccaaagcagcctgtttgaaacggcgagaagag gaaaaggtgtcaggtgtggttggagacccccagatggtgctttcagctccccacccaggc ctgagcgaagcccacaaccccgccgggcacatgtga |
Protein Sequence |
>6929 : length: 651 MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSSTDEVLSLEEK DLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLE QQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM |