| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 7057 |
Name | THBS1 |
Synonym | THBS|THBS-1|TSP|TSP-1|TSP1;thrombospondin 1;THBS1;thrombospondin 1 |
Definition | thrombospondin-1|thrombospondin-1p180 |
Position | 15q15 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 16429 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Malaria;KEGG PATHWAY;hsa05144 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | Integrin cell surface interactions;PID Reactome;500004 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Syndecan-4-mediated signaling events;PID Curated;200115 |
Pathway | ECM-receptor interaction;KEGG PATHWAY;hsa04512 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Pathway | Bladder cancer;KEGG PATHWAY;hsa05219 |
Disease | brain hemorrhage;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;GAD |
Disease | myocardial infarct;GAD |
Disease | stroke, lacunar;GAD |
|
External Links |
|
Links to Entrez Gene | 7057 |
Links to all GeneRIF Items | 7057 |
Links to iHOP | 7057 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7057 : length: 3513 atggggctggcctggggactaggcgtcctgttcctgatgcatgtgtgtggcaccaaccgc attccagagtctggcggagacaacagcgtgtttgacatctttgaactcaccggggccgcc cgcaaggggtctgggcgccgactggtgaagggccccgacccttccagcccagctttccgc atcgaggatgccaacctgatcccccctgtgcctgatgacaagttccaagacctggtggat gctgtgcgggcagaaaagggtttcctccttctggcatccctgaggcagatgaagaagacc cggggcacgctgctggccctggagcggaaagaccactctggccaggtcttcagcgtggtg tccaatggcaaggcgggcaccctggacctcagcctgaccgtccaaggaaagcagcacgtg gtgtctgtggaagaagctctcctggcaaccggccagtggaagagcatcaccctgtttgtg caggaagacagggcccagctgtacatcgactgtgaaaagatggagaatgctgagttggac gtccccatccaaagcgtcttcaccagagacctggccagcatcgccagactccgcatcgca aaggggggcgtcaatgacaatttccagggggtgctgcagaatgtgaggtttgtctttgga accacaccagaagacatcctcaggaacaaaggctgctccagctctaccagtgtcctcctc acccttgacaacaacgtggtgaatggttccagccctgccatccgcactaactacattggc cacaagacaaaggacttgcaagccatctgcggcatctcctgtgatgagctgtccagcatg gtcctggaactcaggggcctgcgcaccattgtgaccacgctgcaggacagcatccgcaaa gtgactgaagagaacaaagagttggccaatgagctgaggcggcctcccctatgctatcac aacggagttcagtacagaaataacgaggaatggactgttgatagctgcactgagtgtcac tgtcagaactcagttaccatctgcaaaaaggtgtcctgccccatcatgccctgctccaat gccacagttcctgatggagaatgctgtcctcgctgttggcccagcgactctgcggacgat ggctggtctccatggtccgagtggacctcctgttctacgagctgtggcaatggaattcag cagcgcggccgctcctgcgatagcctcaacaaccgatgtgagggctcctcggtccagaca cggacctgccacattcaggagtgtgacaagagatttaaacaggatggtggctggagccac tggtccccgtggtcatcttgttctgtgacatgtggtgatggtgtgatcacaaggatccgg ctctgcaactctcccagcccccagatgaacgggaaaccctgtgaaggcgaagcgcgggag accaaagcctgcaagaaagacgcctgccccatcaatggaggctggggtccttggtcacca tgggacatctgttctgtcacctgtggaggaggggtacagaaacgtagtcgtctctgcaac aaccccacaccccagtttggaggcaaggactgcgttggtgatgtaacagaaaaccagatc tgcaacaagcaggactgtccaattgatggatgcctgtccaatccctgctttgccggcgtg aagtgtactagctaccctgatggcagctggaaatgtggtgcttgtccccctggttacagt ggaaatggcatccagtgcacagatgttgatgagtgcaaagaagtgcctgatgcctgcttc aaccacaatggagagcaccggtgtgagaacacggaccccggctacaactgcctgccctgc cccccacgcttcaccggctcacagcccttcggccagggtgtcgaacatgccacggccaac aaacaggtgtgcaagccccgtaacccctgcacggatgggacccacgactgcaacaagaac gccaagtgcaactacctgggccactatagcgaccccatgtaccgctgcgagtgcaagcct ggctacgctggcaatggcatcatctgcggggaggacacagacctggatggctggcccaat gagaacctggtgtgcgtggccaatgcgacttaccactgcaaaaaggataattgccccaac cttcccaactcagggcaggaagactatgacaaggatggaattggtgatgcctgtgatgat gacgatgacaatgataaaattccagatgacagggacaactgtccattccattacaaccca gctcagtatgactatgacagagatgatgtgggagaccgctgtgacaactgtccctacaac cacaacccagatcaggcagacacagacaacaatggggaaggagacgcctgtgctgcagac attgatggagacggtatcctcaatgaacgggacaactgccagtacgtctacaatgtggac cagagagacactgatatggatggggttggagatcagtgtgacaattgccccttggaacac aatccggatcagctggactctgactcagaccgcattggagatacctgtgacaacaatcag gatattgatgaagatggccaccagaacaatctggacaactgtccctatgtgcccaatgcc aaccaggctgaccatgacaaagatggcaagggagatgcctgtgaccacgatgatgacaac gatggcattcctgatgacaaggacaactgcagactcgtgcccaatcccgaccagaaggac tctgacggcgatggtcgaggtgatgcctgcaaagatgattttgaccatgacagtgtgcca gacatcgatgacatctgtcctgagaatgttgacatcagtgagaccgatttccgccgattc cagatgattcctctggaccccaaagggacatcccaaaatgaccctaactgggttgtacgc catcagggtaaagaactcgtccagactgtcaactgtgatcctggactcgctgtaggttat gatgagtttaatgctgtggacttcagtggcaccttcttcatcaacaccgaaagggacgat gactatgctggatttgtctttggctaccagtccagcagccgcttttatgttgtgatgtgg aagcaagtcacccagtcctactgggacaccaaccccacgagggctcagggatactcgggc ctttctgtgaaagttgtaaactccaccacagggcctggcgagcacctgcggaacgccctg tggcacacaggaaacacccctggccaggtgcgcaccctgtggcatgaccctcgtcacata ggctggaaagatttcaccgcctacagatggcgtctcagccacaggccaaagacgggtttc attagagtggtgatgtatgaagggaagaaaatcatggctgactcaggacccatctatgat aaaacctatgctggtggtagactagggttgtttgtcttctctcaagaaatggtgttcttc tctgacctgaaatacgaatgtagagatccctaa |
Protein Sequence |
>7057 : length: 1170 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDP |