| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 7941 |
Name | PLA2G7 |
Synonym | LDL-PLA2|LP-PLA2|PAFAD|PAFAH;phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma);PLA2G7;phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
Definition | 1-alkyl-2-acetylglycerophosphocholine esterase|2-acetyl-1-alkylglycerophosphocholine esterase|LDL-PLA(2)|LDL-associated phospholipase A2|PAF 2-acylhydrolase|PAF acetylhydrolase|gVIIA-PLA2|group-VIIA phospholipase A2|lipoprotein-associated phospholipase A2 |
Position | 6p21.2-p12 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 12881 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Synthesis, Secretion, and Deacylation of Ghrelin;PID Reactome;500141 |
Pathway | Lissencephaly gene (LIS1) in neuronal migration and development;PID Curated;200114 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Ether lipid metabolism;KEGG PATHWAY;hsa00565 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Disease | cholesterol;GAD |
Disease | body mass;GAD |
Disease | cardiomyopathy, nonfamilial hypertrophic;GAD |
Disease | Platelet-activating factor acetylhydrolase deficiency;OMIM |
Disease | Atopy, susceptibility to;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | cardiovascular disease;GAD |
Disease | carotid atherosclerosis;GAD |
Disease | aneurysm, abdominal aortic;GAD |
Disease | Lipoprotein-associated phospholipase A2 activity and mass;NHGRI |
Disease | METABOLIC;GAD |
Disease | coronary artery spasm;GAD |
Disease | myocardial infarct;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | Asthma, susceptibility to;OMIM |
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External Links |
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Links to Entrez Gene | 7941 |
Links to all GeneRIF Items | 7941 |
Links to iHOP | 7941 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7941 : length: 1326 atggtgccacccaaattgcatgtgcttttctgcctctgcggctgcctggctgtggtttat ccttttgactggcaatacataaatcctgttgcccatatgaaatcatcagcatgggtcaac aaaatacaagtactgatggctgctgcaagctttggccaaactaaaatcccccggggaaat gggccttattccgttggttgtacagacttaatgtttgatcacactaataagggcaccttc ttgcgtttatattatccatcccaagataatgatcgccttgacaccctttggatcccaaat aaagaatatttttggggtcttagcaaatttcttggaacacactggcttatgggcaacatt ttgaggttactctttggttcaatgacaactcctgcaaactggaattcccctctgaggcct ggtgaaaaatatccacttgttgttttttctcatggtcttggggcattcaggacactttat tctgctattggcattgacctggcatctcatgggtttatagttgctgctgtagaacacaga gatagatctgcatctgcaacttactatttcaaggaccaatctgctgcagaaataggggac aagtcttggctctaccttagaaccctgaaacaagaggaggagacacatatacgaaatgag caggtacggcaaagagcaaaagaatgttcccaagctctcagtctgattcttgacattgat catggaaagccagtgaagaatgcattagatttaaagtttgatatggaacaactgaaggac tctattgatagggaaaaaatagcagtaattggacattcttttggtggagcaacggttatt cagactcttagtgaagatcagagattcagatgtggtattgccctggatgcatggatgttt ccactgggtgatgaagtatattccagaattcctcagcccctcttttttatcaactctgaa tatttccaatatcctgctaatatcataaaaatgaaaaaatgctactcacctgataaagaa agaaagatgattacaatcaggggttcagtccaccagaattttgctgacttcacttttgca actggcaaaataattggacacatgctcaaattaaagggagacatagattcaaatgtagct attgatcttagcaacaaagcttcattagcattcttacaaaagcatttaggacttcataaa gattttgatcagtgggactgcttgattgaaggagatgatgagaatcttattccagggacc aacattaacacaaccaatcaacacatcatgttacagaactcttcaggaatagagaaatac aattag |
Protein Sequence |
>7941 : length: 441 MVPPKLHVLFCLCGCLAVVYPFDWQYINPVAHMKSSAWVNKIQVLMAAASFGQTKIPRGN GPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNI LRLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHR DRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDID HGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMF PLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFA TGKIIGHMLKLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGT NINTTNQHIMLQNSSGIEKYN |