Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7941

Name

PLA2G7

Synonymous

LDL-PLA2|LP-PLA2|PAFAD|PAFAH;phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma);PLA2G7;phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Definition

1-alkyl-2-acetylglycerophosphocholine esterase|2-acetyl-1-alkylglycerophosphocholine esterase|LDL-PLA(2)|LDL-associated phospholipase A2|PAF 2-acylhydrolase|PAF acetylhydrolase|gVIIA-PLA2|group-VIIA phospholipase A2|lipoprotein-associated phospholipase A2

Position

6p21.2-p12

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

platelet-activating factor acetylhydrolase(h) --> protein remnants (degradation)
PLA2G7(h) --> platelet-activating factor acetylhydrolase(h) (expression).
platelet-activating factor acetylhydrolase(h) --> protein remnants (degradation)
PLA2G7(h) --> platelet-activating factor acetylhydrolase(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

423N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
433N-linked (GlcNAc...).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr6

Promoter: 46810555 - 46812555Agilent_014791

chr6

Promoter: 46810555 - 46812555GSE27584

chr6

Promoter: 46810555 - 46812555Agilent_014791_44K


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