| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8650 |
Name | NUMB |
Synonym | C14orf41|S171|c14_5527;numb homolog (Drosophila);NUMB;numb homolog (Drosophila) |
Definition | h-Numb|protein numb homolog |
Position | 14q24.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 11677 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Notch signaling pathway;KEGG PATHWAY;hsa04330 |
Pathway | Notch signaling pathway;PANTHER;P00045 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | Notch signaling pathway;PID Curated;200013 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Disease | coronary artery calcification;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Coronary artery calcification;NHGRI |
|
External Links |
|
Links to Entrez Gene | 8650 |
Links to all GeneRIF Items | 8650 |
Links to iHOP | 8650 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8650 : length: 1956 atgaacaaattacggcaaagttttaggagaaagaaggatgtttatgttccagaggccagt cgtccacatcagtggcagacagatgaagaaggcgttcgcaccggaaaatgtagcttcccg gttaagtaccttggccatgtagaagttgatgaatcaagaggaatgcacatctgtgaagat gctgtaaaaagattgaaagctgaaaggaagttcttcaaaggcttctttggaaaaactgga aagaaagcagttaaagcagttctgtgggtctcagcagatggactcagagttgtggatgaa aaaactaaggacctcatagttgaccagacgatagagaaagtttctttctgtgccccagac aggaactttgatagagccttttcttacatatgccgtgatggcaccactcgtcgctggatc tgtcactgcttcatggctgtcaaggacacaggtgaaaggttgagccatgcagtaggctgt gcttttgcagcctgtttagagcgcaagcagaagcgggagaaggaatgtggagtgactgct acttttgatgctagtcggaccacttttacaagagaaggatcattccgtgtcacaacagcc actgaacaagcagaaagagaggagatcatgaaacaaatgcaagatgccaagaaagctgaa acagataagatagtcgttggttcatcagttgcccctggcaacactgccccatccccatcc tctcccacctctcctacttctgatgccacgacctctctggagatgaacaatcctcatgcc atcccacgccggcatgctccaattgaacagcttgctcgccaaggctctttccgaggtttt cctgctcttagccagaagatgtcaccctttaaacgccaactatccctacgcatcaatgag ttgccttccactatgcagaggaagactgatttccccattaaaaatgcagtgccagaagta gaaggggaggcagagagcatcagctccctgtgctcacagatcaccaatgccttcagcaca cctgaggaccccttctcatctgctccgatgaccaaaccagtgacagtggtggcaccacaa tctcctaccttccaagctaatggcactgactcagccttccatgtgcttgctaagccagcc catactgctctagcacccgtagcaatgcctgtgcgtgaaaccaacccttgggcccatgcc cctgatgctgctaacaaggaaattgcagccacatgttcggggaccgagtggggtcaatct tctggtgctgcctctccaggtctcttccaggccggtcatagacgtactccctctgaggcc gaccgatggttagaagaggtgtctaagagcgtccgggctcagcagccccaggcctcagct gctcctctgcagccagttctccagcctcctccacccactgccatctcccagccagcatca cctttccaagggaatgcattcctcacctctcagcctgtgccagtgggtgtggtcccagcc ctgcaaccagcctttgtccctgcccagtcctatcctgtggccaatggaatgccctatcca gcccctaatgtgcctgtggtgggcatcactccctcccagatggtggccaacgtatttggc actgcaggccaccctcaggctgcccatccccatcagtcacccagcctggtcaggcagcag acattccctcactacgaggcaagcagtgctaccaccagtcccttctttaagcctcctgct cagcacctcaacggttctgcagctttcaatggtgtagatgatggcaggttggcctcagca gacaggcatacagaggttcctacaggcacctgcccagtggatccttttgaagcccagtgg gctgcattagaaaataagtccaagcagcgtactaatccctcccctaccaaccctttctcc agtgacttacagaagacgtttgaaattgaactttaa |
Protein Sequence |
>8650 : length: 651 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL |