Entrez Gene

Basic Information
Gene ID	8650
Name	NUMB
Synonymous	C14orf41\|S171\|c14_5527;numb homolog (Drosophila);NUMB;numb homolog (Drosophila)
Definition	h-Numb\|protein numb homolog
Position	14q24.3
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
LNX-1(m) + Numb(h) <==> LNX-1(m):Numb(h) (binding)
Numb(h) + ubiquitin(h) --LNX-1(m)--> Numb(h){ub} (ubiquitination)
Numb(h) + Siah1(h) <==> Numb(h):Siah1(h) (binding)
mdm2(m) + Numb(h) <==> mdm2(m):Numb(h) (binding)
Numb(h) + RIP1(h) <==> Numb(h):RIP1(h) (binding)
ErbB1-p170(h){pY1016} + Numb(h) <==> ErbB1-p170(h){pY1016}:Numb(h) (binding)
brca1(m.s.) + Numb(h) <==> brca1(m.s.):Numb(h) (binding)
Numb(h) + P-selectin(h) <==> Numb(h):P-selectin(h) (binding)
NUMB(h) --> Numb(h) (expression).
NUMB(h) --> Numb-isoform1(h) (expression).
NUMB(h) --> Numb-isoform2(h) (expression).
Numb-isoform3(h) + P-selectin(m.s.) <==> Numb-isoform3(h):P-selectin(m.s.) (binding)
NUMB(h) --> Numb-isoform3(h) (expression).
CRMP2(h) + Numb-isoform4(h) <==> CRMP2(h):Numb-isoform4(h) (binding)
CRMP2(r) + Numb-isoform4(h) <==> CRMP2(r):Numb-isoform4(h) (binding)
alpha-adaptin(r) + Numb-isoform4(h) <==> alpha-adaptin(r):Numb-isoform4(h) (binding)
NUMB(h) --> Numb-isoform4(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
276	Phosphoserine.		Swiss-Prot 53.0
295	Phosphoserine.		Swiss-Prot 53.0
631	Phosphothreonine (By similarity).		Swiss-Prot 53.0
634	Phosphoserine.		Swiss-Prot 53.0
438	Phosphoserine	17081983	Phospho.ELM 6.0