| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 9353 |
Name | SLIT2 |
Synonym | SLIL3|Slit-2;slit homolog 2 (Drosophila);SLIT2;slit homolog 2 (Drosophila) |
Definition | slit homolog 2 protein |
Position | 4p15.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 15351 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Axon guidance mediated by Slit/Robo;PANTHER;P00008 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Glypican 1 network;PID Curated;200021 |
Pathway | Regulation of Commissural axon pathfinding by Slit and Robo;PID Reactome;500093 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Signaling by Robo receptor;PID Reactome;500092 |
Disease | Pulmonary fibrosis;FunDO |
Disease | Echocardiographic traits;NHGRI |
Disease | Cancer;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Echocardiographic traits;GAD |
|
External Links |
|
Links to Entrez Gene | 9353 |
Links to all GeneRIF Items | 9353 |
Links to iHOP | 9353 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>9353 : length: 4590 atgcgcggcgttggctggcagatgctgtccctgtcgctggggttagtgctggcgatcctg aacaaggtggcaccgcaggcgtgcccggcgcagtgctcttgctcgggcagcacagtggac tgtcacgggctggcgctgcgcagcgtgcccaggaatatcccccgcaacaccgagagactg gatttaaatggaaataacatcacaagaattacgaagacagattttgctggtcttagacat ctaagagttcttcagcttatggagaataagattagcaccattgaaagaggagcattccag gatcttaaagaactagagagactgcgtttaaacagaaatcaccttcagctgtttcctgag ttgctgtttcttgggactgcgaagctatacaggcttgatctcagtgaaaaccaaattcag gcaatcccaaggaaagctttccgtggggcagttgacataaaaaatttgcaactggattac aaccagatcagctgtattgaagatggggcattcagggctctccgggacctggaagtgctc actctcaacaataacaacattactagactttctgtggcaagtttcaaccatatgcctaaa cttaggacttttcgactgcattcaaacaacctgtattgtgactgccacctggcctggctc tccgactggcttcgccaaaggcctcgggttggtctgtacactcagtgtatgggcccctcc cacctgagaggccataatgtagccgaggttcaaaaacgagaatttgtctgcagtggtcac cagtcatttatggctccttcttgtagtgttttgcactgccctgccgcctgtacctgtagc aacaatatcgtagactgtcgtgggaaaggtctcactgagatccccacaaatcttccagag accatcacagaaatacgtttggaacagaacacaatcaaagtcatccctcctggagctttc tcaccatataaaaagcttagacgaattgacctgagcaataatcagatctctgaacttgca ccagatgctttccaaggactacgctctctgaattcacttgtcctctatggaaataaaatc acagaactccccaaaagtttatttgaaggactgttttccttacagctcctattattgaat gccaacaagataaactgccttcgggtagatgcttttcaggatctccacaacttgaacctt ctctccctatatgacaacaagcttcagaccatcgccaaggggaccttttcacctcttcgg gccattcaaactatgcatttggcccagaacccctttatttgtgactgccatctcaagtgg ctagcggattatctccataccaacccgattgagaccagtggtgcccgttgcaccagcccc cgccgcctggcaaacaaaagaattggacagatcaaaagcaagaaattccgttgttcagct aaagaacagtatttcattccaggtacagaagattatcgatcaaaattaagtggagactgc tttgcggatctggcttgccctgaaaagtgtcgctgtgaaggaaccacagtagattgctct aatcaaaagctcaacaaaatcccggagcacattccccagtacactgcagagttgcgtctc aataataatgaatttaccgtgttggaagccacaggaatctttaagaaacttcctcaatta cgtaaaataaactttagcaacaataagatcacagatattgaggagggagcatttgaagga gcatctggtgtaaatgaaatacttcttacgagtaatcgtttggaaaatgtgcagcataag atgttcaagggattggaaagcctcaaaactttgatgttgagaagcaatcgaataacctgt gtggggaatgacagtttcataggactcagttctgtgcgtttgctttctttgtatgataat caaattactacagttgcaccaggggcatttgatactctccattctttatctactctaaac ctcttggccaatccttttaactgtaactgctacctggcttggttgggagagtggctgaga aagaagagaattgtcacgggaaatcctagatgtcaaaaaccatacttcctgaaagaaata cccatccaggatgtggccattcaggacttcacttgtgatgacggaaatgatgacaatagt tgctccccactttctcgctgtcctactgaatgtacttgcttggatacagtcgtccgatgt agcaacaagggtttgaaggtcttgccgaaaggtattccaagagatgtcacagagttgtat ctggatggaaaccaatttacactggttcccaaggaactctccaactacaaacatttaaca cttatagacttaagtaacaacagaataagcacgctttctaatcagagcttcagcaacatg acccagctcctcaccttaattcttagttacaaccgtctgagatgtattcctcctcgcacc tttgatggattaaagtctcttcgattactttctctacatggaaatgacatttctgttgtg cctgaaggtgctttcaatgatctttctgcattatcacatctagcaattggagccaaccct ctttactgtgattgtaacatgcagtggttatccgactgggtgaagtcggaatataaggag cctggaattgctcgttgtgctggtcctggagaaatggcagataaacttttactcacaact ccctccaaaaaatttacctgtcaaggtcctgtggatgtcaatattctagctaagtgtaac ccctgcctatcaaatccgtgtaaaaatgatggcacatgtaatagtgatccagttgacttt taccgatgcacctgtccatatggtttcaaggggcaggactgtgatgtcccaattcatgcc tgcatcagtaacccatgtaaacatggaggaacttgccacttaaaggaaggagaagaagat ggattctggtgtatttgtgctgatggatttgaaggagaaaattgtgaagtcaacgttgat gattgtgaagataatgactgtgaaaataattctacatgtgtcgatggcattaataactac acatgcctttgcccacctgagtatacaggtgagttgtgtgaggagaagctggacttctgt gcccaggacctgaacccctgccagcacgattcaaagtgcatcctaactccaaagggattc aaatgtgactgcacaccagggtacgtaggtgaacactgcgacatcgattttgacgactgc caagacaacaagtgtaaaaacggagcccactgcacagatgcagtgaacggctatacgtgc atatgccccgaaggttacagtggcttgttctgtgagttttctccacccatggtcctccct cgtaccagcccctgtgataattttgattgtcagaatggagctcagtgtatcgtcagaata aatgagccaatatgtcagtgtttgcctggctatcagggagaaaagtgtgaaaaattggtt agtgtgaattttataaacaaagagtcttatcttcagattccttcagccaaggttcggcct cagacgaacataacacttcagattgccacagatgaagacagcggaatcctcctgtataag ggtgacaaagaccatatcgcggtagaactctatcgggggcgtgttcgtgccagctatgac accggctctcatccagcttctgccatttacagtgtggagacaatcaatgatggaaacttc cacattgtggaactacttgccttggatcagagtctctctttgtccgtggatggtgggaac cccaaaatcatcactaacttgtcaaagcagtccactctgaattttgactctccactctat gtaggaggcatgccagggaagagtaacgtggcatctctgcgccaggcccctgggcagaac ggaaccagcttccacggctgcatccggaacctttacatcaacagtgagctgcaggacttc cagaaggtgccgatgcaaacaggcattttgcctggctgtgagccatgccacaagaaggtg tgtgcccatggcacatgccagcccagcagccaggcaggcttcacctgcgagtgccaggaa ggatggatggggcccctctgtgaccaacggaccaatgacccttgccttggaaataaatgc gtacatggcacctgcttgcccatcaatgcgttctcctacagctgtaagtgcttggagggc catggaggtgtcctctgtgatgaagaggaggatctgtttaacccatgccaggcgatcaag tgcaagcacgggaagtgcaggctttcaggtctggggcagccctactgtgaatgcagcagt ggatacacgggggacagctgtgatcgagaaatctcttgtcgaggggaaaggataagagat tattaccaaaagcagcagggctatgctgcttgccaaacaaccaagaaggtgtcccgatta gagtgcagaggtgggtgtgcaggagggcagtgctgtggaccgctgaggagcaagcggcgg aaatactctttcgaatgcactgacggctcctcctttgtggacgaggttgagaaagtggtg aagtgcggctgtacgaggtgtgtgtcctaa |
Protein Sequence |
>9353 : length: 1529 MRGVGWQMLSLSLGLVLAILNKVAPQACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERL DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPE LLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVL TLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPS HLRGHNVAEVQKREFVCSGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPE TITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKI TELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLR AIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSA KEQYFIPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRL NNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHK MFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLN LLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNS CSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLT LIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVV PEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTT PSKKFTCQGPVDVNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHA CISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNY TCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDC QDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRI NEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRPQTNITLQIATDEDSGILLYK GDKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNFHIVELLALDQSLSLSVDGGN PKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDF QKVPMQTGILPGCEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC VHGTCLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSS GYTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQCCGPLRSKRR KYSFECTDGSSFVDEVEKVVKCGCTRCVS |