| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 9429 |
Name | ABCG2 |
Synonym | ABC15|ABCP|BCRP|BCRP1|BMDP|CD338|CDw338|EST157481|GOUT1|MRX|MXR|MXR1|UAQTL1;ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group);ABCG2;ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
Definition | ABC transporter|ATP-binding cassette sub-family G member 2|ATP-binding cassette transporter G2|breast cancer resistance protein|mitoxantrone resistance-associated protein|multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) mem |
Position | 4q22 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 2237 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | ABC transporters;KEGG PATHWAY;hsa02010 |
Pathway | HIF-2-alpha transcription factor network;PID Curated;200030 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Disease | Heart failure;FunDO |
Disease | Lymphoma, Large B-Cell, Diffuse;GAD |
Disease | lymphoma;GAD |
Disease | Abortion;FunDO |
Disease | serum urate;GAD |
Disease | PHARMACOGENOMIC;GAD |
Disease | Serum uric acid;NHGRI |
Disease | Gallbladder disease;FunDO |
Disease | serum uric acid;GAD |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | Skin disease, Genetic;FunDO |
Disease | Serum urate;NHGRI |
Disease | Neoplasms;GAD |
Disease | cancer;GAD |
Disease | kidney cancer;GAD |
Disease | Diarrhea;GAD |
Disease | rosuvastatin pharmacokinetics;GAD |
Disease | irinotecan pharmacokinetics irinotecan toxicity lung cancer;GAD |
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External Links |
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Links to Entrez Gene | 9429 |
Links to all GeneRIF Items | 9429 |
Links to iHOP | 9429 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>9429 : length: 1968 atgtcttccagtaatgtcgaagtttttatcccagtgtcacaaggaaacaccaatggcttc cccgcgacagcttccaatgacctgaaggcatttactgaaggagctgtgttaagttttcat aacatctgctatcgagtaaaactgaagagtggctttctaccttgtcgaaaaccagttgag aaagaaatattatcgaatatcaatgggatcatgaaacctggtctcaacgccatcctggga cccacaggtggaggcaaatcttcgttattagatgtcttagctgcaaggaaagatccaagt ggattatctggagatgttctgataaatggagcaccgcgacctgccaatttcaaatgtaat tcaggttacgtggtacaagatgatgttgtgatgggcactctgacggtgagagaaaactta cagttctcagcagctcttcggcttgcaacaactatgacgaatcatgaaaaaaacgaacgg attaacagggtcattcaagagttaggtctggataaagtggcagactccaaggttggaact cagtttatccgtggtgtgtctggaggagaaagaaaaaggactagtataggaatggagctt atcactgatccttccatcttgttcttggatgagcctacaactggcttagactcaagcaca gcaaatgctgtccttttgctcctgaaaaggatgtctaagcagggacgaacaatcatcttc tccattcatcagcctcgatattccatcttcaagttgtttgatagcctcaccttattggcc tcaggaagacttatgttccacgggcctgctcaggaggccttgggatactttgaatcagct ggttatcactgtgaggcctataataaccctgcagacttcttcttggacatcattaatgga gattccactgctgtggcattaaacagagaagaagactttaaagccacagagatcatagag ccttccaagcaggataagccactcatagaaaaattagcggagatttatgtcaactcctcc ttctacaaagagacaaaagctgaattacatcaactttccgggggtgagaagaagaagaag atcacagtcttcaaggagatcagctacaccacctccttctgtcatcaactcagatgggtt tccaagcgttcattcaaaaacttgctgggtaatccccaggcctctatagctcagatcatt gtcacagtcgtactgggactggttataggtgccatttactttgggctaaaaaatgattct actggaatccagaacagagctggggttctcttcttcctgacgaccaaccagtgtttcagc agtgtttcagccgtggaactctttgtggtagagaagaagctcttcatacatgaatacatc agcggatactacagagtgtcatcttatttccttggaaaactgttatctgatttattaccc atgaggatgttaccaagtattatatttacctgtatagtgtacttcatgttaggattgaag ccaaaggcagatgccttcttcgttatgatgtttacccttatgatggtggcttattcagcc agttccatggcactggccatagcagcaggtcagagtgtggtttctgtagcaacacttctc atgaccatctgttttgtgtttatgatgattttttcaggtctgttggtcaatctcacaacc attgcatcttggctgtcatggcttcagtacttcagcattccacgatatggatttacggct ttgcagcataatgaatttttgggacaaaacttctgcccaggactcaatgcaacaggaaac aatccttgtaactatgcaacatgtactggcgaagaatatttggtaaagcagggcatcgat ctctcaccctggggcttgtggaagaatcacgtggccttggcttgtatgattgttattttc ctcacaattgcctacctgaaattgttatttcttaaaaaatattcttaa |
Protein Sequence |
>9429 : length: 655 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS |