| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 9429 |
Name | ABCG2 |
Synonymous | ABC15|ABCP|BCRP|BCRP1|BMDP|CD338|CDw338|EST157481|GOUT1|MRX|MXR|MXR1|UAQTL1;ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group);ABCG2;ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
Definition | ABC transporter|ATP-binding cassette sub-family G member 2|ATP-binding cassette transporter G2|breast cancer resistance protein|mitoxantrone resistance-associated protein|multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) mem |
Position | 4q22 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
ABCG2(h) --> CDw338 isoform1(h) (expression). | CDw338(h) + pim1(h) <==> CDw338(h):pim1(h) (binding) | CDw338(h) + ATP --> CDw338(h){pT} + ADP (phosphorylation) | CDw338(h) + ATP --pim1(h)--> CDw338(h){pT362} + ADP (phosphorylation) | 2 CDw338(h) <==> (CDw338(h))2 (binding) | n CDw338(h) <==> (CDw338(h))n (binding) | ABCG2(h) --> CDw338(h) (expression). | ABCG2(h) --> CDw338 isoform2(h) (expression). | ABCG2(h) --> ABCG2(h) (expression). | hsa-miR-519c --/ ABCG2(h) (increase of mRNA decay). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
596 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr4 |
Promoter: 89298535 - 89300535 | Agilent_014791 |
chr4 |
Promoter: 89298535 - 89300535 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 89298535 - 89300535 | GSE27584 |
chr4 |
Promoter: 89298535 - 89300535 | Agilent_014791_44K |
chr4 |
Promoter: 89298535 - 89300535 | PMID:16954373 |