Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1147

Name

CHUK

Synonymous

IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16;conserved helix-loop-helix ubiquitous kinase;CHUK;conserved helix-loop-helix ubiquitous kinase

Definition

I-kappa-B kinase 1|I-kappa-B kinase-alpha|IKK-a kinase|IkB kinase alpha subunit|Nuclear factor NFkappaB inhibitor kinase alpha|TCF-16|inhibitor of nuclear factor kappa-B kinase subunit alpha|transcription factor 16

Position

10q24-q25

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 CDC37CELL_MAP;

in same component

 ERC1NCI_NATURE;

in same component

 FADDREACTOME;

in same component

 HSP90AA1CELL_MAP;

in same component

 IKBKBNCI_NATURE;

in same component

 IKBKBREACTOME;

in same component

 IKBKGNCI_NATURE;

in same component

 IKBKGREACTOME;

in same component

 IRAK1REACTOME;

in same component

 LY96REACTOME;

in same component

 MAVSREACTOME;

in same component

 PRKCANCI_NATURE;

in same component

 RIPK1REACTOME;

in same component

 TICAM1REACTOME;

in same component

 TICAM2REACTOME;

in same component

 TLR4REACTOME;

in same component

 TRAF6REACTOME;

interacts with

 AHSA1INTACT;

interacts with

 AKAP8LHPRD;

interacts with

 AKT1BIOGRID;

interacts with

 AKT1CELL_MAP;

interacts with

 AKT1HPRD;

interacts with

 AKT2BIOGRID;

interacts with

 AKT2CELL_MAP;

interacts with

 AKT2HPRD;

interacts with

 ANKRD28HPRD;

interacts with

 ARRB1HPRD;

interacts with

 ARRB2HPRD;

interacts with

 AURKAHPRD;

interacts with

 BAG2INTACT;

interacts with

 BCL10HPRD;

interacts with

 CACYBPINTACT;

interacts with

 CALD1INTACT;

interacts with

 CALM1MINT;

interacts with

 CASP8BIOGRID;

interacts with

 CASP8HPRD;

interacts with

 CCDC117INTACT;

interacts with

 CD3EAPHPRD;

interacts with

 CDC37BIOGRID;

interacts with

 CDC37CELL_MAP;

interacts with

 CDC37HPRD;

interacts with

 CDC37INTACT;

interacts with

 CDC37MINT;

interacts with

 CDK11AINTACT;

interacts with

 CEP97INTACT;

interacts with

 CHEK1HPRD;

interacts with

 CHORDC1INTACT;

interacts with

 CNOT6INTACT;

interacts with

 CNTN2BIOGRID;

interacts with

 COPB2HPRD;

interacts with

 CREBBPCELL_MAP;

interacts with

 CREBBPHPRD;

interacts with

 CSF2RAHPRD;

interacts with

 CskCELL_MAP;

interacts with

 CSNK1A1INTACT;

interacts with

 CTNNB1BIOGRID;

interacts with

 CTNNB1HPRD;

interacts with

 CUEDC2BIOGRID;

interacts with

 CUL1BIOGRID;

interacts with

 CUL1HPRD;

interacts with

 DDX3XHPRD;

interacts with

 DUSP1BIOGRID;

interacts with

 DYNC1H1INTACT;

interacts with

 EDRF1INTACT;

interacts with

 EFTUD2INTACT;

interacts with

 EIF2AK2BIOGRID;

interacts with

 EIF2AK2HPRD;

interacts with

 EP300BIOGRID;

interacts with

 ESR1HPRD;

interacts with

 FAM83HINTACT;

interacts with

 FANCABIOGRID;

interacts with

 FBLHPRD;

interacts with

 FBXW11HPRD;

interacts with

 FBXW7HPRD;

interacts with

 FKBP4INTACT;

interacts with

 FKBP5CELL_MAP;

interacts with

 FKBP5INTACT;

interacts with

 FKBP5MINT;

interacts with

 FLIIINTACT;

interacts with

 FOXO3HPRD;

interacts with

 GLG1HPRD;

interacts with

 GTF2IHPRD;

interacts with

 HIST2H3ABIOGRID;

interacts with

 HIST3H3HPRD;

interacts with

 HSP90AA1CELL_MAP;

interacts with

 HSP90AA1HPRD;

interacts with

 HSP90AA1INTACT;

interacts with

 HSP90AA1MINT;

interacts with

 HSP90AB1CELL_MAP;

interacts with

 HSP90AB1HPRD;

interacts with

 HSP90AB1INTACT;

interacts with

 HSP90AB1MINT;

interacts with

 IKBKAPBIOGRID;

interacts with

 IKBKAPHPRD;

interacts with

 IKBKBBIOGRID;

interacts with

 IKBKBHPRD;

interacts with

 IKBKBMINT;

interacts with

 IKBKEHPRD;

interacts with

 IKBKGBIOGRID;

interacts with

 IKBKGINTACT;

interacts with

 IKBKGMINT;

interacts with

 IQGAP2HPRD;

interacts with

 IRAK1BIOGRID;

interacts with

 IRAK1HPRD;

interacts with

 IRS1BIOGRID;

interacts with

 IRS1HPRD;

interacts with

 KPNA2HPRD;

interacts with

 KPNA3HPRD;

interacts with

 LRPPRCHPRD;

interacts with

 MAP3K11BIOGRID;

interacts with

 MAP3K11HPRD;

interacts with

 MAP3K14BIOGRID;

interacts with

 MAP3K14CELL_MAP;

interacts with

 MAP3K14HPRD;

interacts with

 MAP3K14MINT;

interacts with

 MAP3K3MINT;

interacts with

 MAP3K7BIOGRID;

interacts with

 MAP3K7HPRD;

interacts with

 MAP3K8BIOGRID;

interacts with

 MAP3K8HPRD;

interacts with

 MCCHPRD;

interacts with

 MTIF2HPRD;

interacts with

 MYCINTACT;

interacts with

 MYH14MINT;

interacts with

 MYH9MINT;

interacts with

 MYL12AMINT;

interacts with

 MYL6MINT;

interacts with

 MYLK2INTACT;

interacts with

 MYO1DMINT;

interacts with

 NCOA3BIOGRID;

interacts with

 NCOA3HPRD;

interacts with

 NCOR2BIOGRID;

interacts with

 NCOR2HPRD;

interacts with

 NFKB1BIOGRID;

interacts with

 NFKB1CELL_MAP;

interacts with

 NFKB1HPRD;

interacts with

 Nfkb1MINT;

interacts with

 NFKB1MINT;

interacts with

 NFKB2BIOGRID;

interacts with

 NFKB2CELL_MAP;

interacts with

 NFKB2HPRD;

interacts with

 NFKB2MINT;

interacts with

 NFKBIABIOGRID;

interacts with

 NFKBIACELL_MAP;

interacts with

 NFKBIAHPRD;

interacts with

 NFKBIAMINT;

interacts with

 NFKBIBBIOGRID;

interacts with

 NFKBIBCELL_MAP;

interacts with

 NFKBIBHPRD;

interacts with

 NFKBIBMINT;

interacts with

 NFKBIEHPRD;

interacts with

 NFKBIEMINT;

interacts with

 NLRP4BIOGRID;

interacts with

 NLRP4CELL_MAP;

interacts with

 NLRP4HPRD;

interacts with

 NOTCH3HPRD;

interacts with

 Notch3MINT;

interacts with

 Nr2c2CELL_MAP;

interacts with

 NR2C2HPRD;

interacts with

 NUDCINTACT;

interacts with

 NUDCD3INTACT;

interacts with

 PDCD2HPRD;

interacts with

 Pebp1BIOGRID;

interacts with

 PEBP1CELL_MAP;

interacts with

 PEBP1HPRD;

interacts with

 PIAS1HPRD;

interacts with

 POLR1AHPRD;

interacts with

 POLR1BHPRD;

interacts with

 POLR1DHPRD;

interacts with

 POLR1EHPRD;

interacts with

 POLR2EINTACT;

interacts with

 POLR2HHPRD;

interacts with

 PPM1BBIOGRID;

interacts with

 PPP2R1AINTACT;

interacts with

 PPP5CINTACT;

interacts with

 PPP6CHPRD;

interacts with

 PPP6R1HPRD;

interacts with

 PPP6R2HPRD;

interacts with

 PRKCABIOGRID;

interacts with

 PRKCBHPRD;

interacts with

 PRKCDBIOGRID;

interacts with

 PRKCIBIOGRID;

interacts with

 PRKCIHPRD;

interacts with

 PRKCQBIOGRID;

interacts with

 PRKCQHPRD;

interacts with

 PRKDCBIOGRID;

interacts with

 PRKDCHPRD;

interacts with

 PRPF8INTACT;

interacts with

 PRR14LINTACT;

interacts with

 PTGES3INTACT;

interacts with

 PTPN11CELL_MAP;

interacts with

 PTPN11HPRD;

interacts with

 RASAL2HPRD;

interacts with

 RELABIOGRID;

interacts with

 RELAHPRD;

interacts with

 RelaMINT;

interacts with

 RELAMINT;

interacts with

 RELBHPRD;

interacts with

 RELBMINT;

interacts with

 RELHPRD;

interacts with

 RMPINTACT;

interacts with

 RPAP3INTACT;

interacts with

 RPL4HPRD;

interacts with

 RPL6HPRD;

interacts with

 SCRIBINTACT;

interacts with

 SEC16AHPRD;

interacts with

 SKP1HPRD;

interacts with

 SNRNP200INTACT;

interacts with

 SPAG9HPRD;

interacts with

 SRCHPRD;

interacts with

 STAP2HPRD;

interacts with

 STUB1INTACT;

interacts with

 SUGT1INTACT;

interacts with

 TAB1INTACT;

interacts with

 TAB2INTACT;

interacts with

 TANKBIOGRID;

interacts with

 TANKHPRD;

interacts with

 TFIP11INTACT;

interacts with

 TNFAIP3BIOGRID;

interacts with

 TNFAIP3HPRD;

interacts with

 TNFBIOGRID;

interacts with

 TNFRSF1AHPRD;

interacts with

 TNIP2HPRD;

interacts with

 TOMM34INTACT;

interacts with

 TP73BIOGRID;

interacts with

 TPM3MINT;

interacts with

 TRAF2BIOGRID;

interacts with

 TRAF2HPRD;

interacts with

 TRAF3IP2BIOGRID;

interacts with

 TRAF3IP2HPRD;

interacts with

 TRPC4APBIOGRID;

interacts with

 Trpc4apCELL_MAP;

interacts with

 TRPC4APHPRD;

interacts with

 TTC4INTACT;

interacts with

 TTC9CINTACT;

interacts with

 TUBA3CMINT;

interacts with

 TUBB4MINT;

interacts with

 TUBBMINT;

interacts with

 UBE2E3HPRD;

interacts with

 UBE2IBIOGRID;

interacts with

 UBE2NBIOGRID;

interacts with

 UNC45AINTACT;

interacts with

 USP19INTACT;

Metabolic Interaction   [Top]

There is no record for CHUK

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 CDC37CELL_MAP;

reacts with

 CHUKCELL_MAP;

reacts with

 CHUKNCI_NATURE;

reacts with

 CHUKREACTOME;

reacts with

 ERC1NCI_NATURE;

reacts with

 FADDREACTOME;

reacts with

 HSP90AA1CELL_MAP;

reacts with

 IKBKBNCI_NATURE;

reacts with

 IKBKBREACTOME;

reacts with

 IKBKGNCI_NATURE;

reacts with

 IKBKGREACTOME;

reacts with

 IRAK1REACTOME;

reacts with

 LY96REACTOME;

reacts with

 MAVSREACTOME;

reacts with

 PRKCANCI_NATURE;

reacts with

 RIPK1REACTOME;

reacts with

 TICAM1REACTOME;

reacts with

 TICAM2REACTOME;

reacts with

 TLR4REACTOME;

reacts with

 TNFAIP3NCI_NATURE;

reacts with

 TRAF6REACTOME;

reacts with

 UBE2NREACTOME;

reacts with

 UBE2V1REACTOME;

state change

 AKT1CELL_MAP;

state change

 AKT1NCI_NATURE;

state change

 AKT2CELL_MAP;

state change

 BCL10NCI_NATURE;

state change

 BCL10REACTOME;

state change

 CARD11NCI_NATURE;

state change

 CARD11REACTOME;

state change

 CHUKCELL_MAP;

state change

 IRAK1NCI_NATURE;

state change

 MALT1NCI_NATURE;

state change

 MALT1REACTOME;

state change

 MAP3K14CELL_MAP;

state change

 MAP3K14NCI_NATURE;

state change

 MAP3K1REACTOME;

state change

 MAP3K3NCI_NATURE;

state change

 MAP3K7NCI_NATURE;

state change

 MAP3K7REACTOME;

state change

 MAVSREACTOME;

state change

 PDPK1REACTOME;

state change

 PRKCBNCI_NATURE;

state change

 RIPK1REACTOME;

state change

 SQSTM1NCI_NATURE;

state change

 SRCCELL_MAP;

state change

 TAB1NCI_NATURE;

state change

 TAB2NCI_NATURE;

state change

 TAB2REACTOME;

state change

 TICAM1REACTOME;

state change

 TLR3REACTOME;

state change

 TNFNCI_NATURE;

state change

 TNFRSF1ANCI_NATURE;

state change

 TRAF6NCI_NATURE;

state change

 TRAF6REACTOME;

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