| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1796 |
Name | DOK1 |
Synonymous | P62DOK;docking protein 1, 62kDa (downstream of tyrosine kinase 1);DOK1;docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
Definition | Downstream of tyrosine kinase 1|docking protein 1|docking protein 1 (downstream of tyrosine kinase 1)|p62(dok)|pp62 |
Position | 2p13 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
in same component |
ABL1 | IMID; |
in same component |
FCER1A | NCI_NATURE; |
in same component |
FCER1G | NCI_NATURE; |
in same component |
FCGR2B | NCI_NATURE; |
in same component |
GDNF | NCI_NATURE; |
in same component |
GFRA1 | NCI_NATURE; |
in same component |
INPP5D | NCI_NATURE; |
in same component |
LYN | CELL_MAP; |
in same component |
LYN | NCI_NATURE; |
in same component |
MS4A2 | NCI_NATURE; |
in same component |
NCK1 | IMID; |
in same component |
NCK1 | NCI_NATURE; |
in same component |
RASA1 | NCI_NATURE; |
in same component |
RASGRP3 | IMID; |
in same component |
TEC | NCI_NATURE; |
interacts with |
ABL1 | BIOGRID; |
interacts with |
CRKL | BIOGRID; |
interacts with |
CRKL | CELL_MAP; |
interacts with |
CRKL | HPRD; |
interacts with |
CSK | HPRD; |
interacts with |
Dlg4 | MINT; |
interacts with |
DOK2 | BIOGRID; |
interacts with |
ERBB2 | MINT; |
interacts with |
FES | CELL_MAP; |
interacts with |
FES | HPRD; |
interacts with |
FGR | BIOGRID; |
interacts with |
FGR | CELL_MAP; |
interacts with |
FYN | HPRD; |
interacts with |
GRB10 | HPRD; |
interacts with |
HCK | BIOGRID; |
interacts with |
HCK | CELL_MAP; |
interacts with |
HCK | HPRD; |
interacts with |
INPP5D | BIOGRID; |
interacts with |
INPP5D | CELL_MAP; |
interacts with |
INPP5D | HPRD; |
interacts with |
INSR | HPRD; |
interacts with |
ITGB1 | HPRD; |
interacts with |
ITGB2 | HPRD; |
interacts with |
ITGB3 | HPRD; |
interacts with |
ITGB5 | HPRD; |
interacts with |
ITGB7 | HPRD; |
interacts with |
KIT | BIOGRID; |
interacts with |
KIT | CELL_MAP; |
interacts with |
KIT | HPRD; |
interacts with |
LCK | HPRD; |
interacts with |
LYN | BIOGRID; |
interacts with |
LYN | CELL_MAP; |
interacts with |
LYN | HPRD; |
interacts with |
MAP4K4 | HPRD; |
interacts with |
NCK1 | HPRD; |
interacts with |
NCK2 | BIOGRID; |
interacts with |
NCK2 | HPRD; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PIK3R1 | CELL_MAP; |
interacts with |
PIK3R2 | CELL_MAP; |
interacts with |
PLCG1 | BIOGRID; |
interacts with |
PLCG1 | CELL_MAP; |
interacts with |
PTPN11 | MINT; |
interacts with |
PTPN6 | HPRD; |
interacts with |
PTPRH | HPRD; |
interacts with |
RASA1 | BIOGRID; |
interacts with |
RASA1 | CELL_MAP; |
interacts with |
RASA1 | HPRD; |
interacts with |
SH2D1A | BIOGRID; |
interacts with |
SH2D1A | HPRD; |
interacts with |
SH2D1A | MINT; |
interacts with |
SHC1 | BIOGRID; |
interacts with |
SHC1 | CELL_MAP; |
interacts with |
SHC1 | HPRD; |
interacts with |
SRC | BIOGRID; |
interacts with |
SRC | CELL_MAP; |
interacts with |
SRC | HPRD; |
interacts with |
TEC | BIOGRID; |
interacts with |
TEC | HPRD; |
interacts with |
YES1 | BIOGRID; |
interacts with |
YES1 | CELL_MAP; |
interacts with |
YES1 | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for DOK1 | ||
Signaling Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
ABL1 | IMID; |
reacts with |
DOK1 | IMID; |
reacts with |
DOK1 | NCI_NATURE; |
reacts with |
FCER1A | NCI_NATURE; |
reacts with |
FCER1G | NCI_NATURE; |
reacts with |
FCGR2B | NCI_NATURE; |
reacts with |
GDNF | NCI_NATURE; |
reacts with |
GFRA1 | NCI_NATURE; |
reacts with |
INPP5D | NCI_NATURE; |
reacts with |
LYN | NCI_NATURE; |
reacts with |
MS4A2 | NCI_NATURE; |
reacts with |
NCK1 | IMID; |
reacts with |
NCK1 | NCI_NATURE; |
reacts with |
RASA1 | NCI_NATURE; |
reacts with |
RASGRP3 | IMID; |
reacts with |
TEC | NCI_NATURE; |
state change |
CD79A | NCI_NATURE; |
state change |
CD79B | NCI_NATURE; |
state change |
DUSP1 | NCI_NATURE; |
state change |
EFNB2 | IMID; |
state change |
FCGR2B | NCI_NATURE; |
state change |
FYN | CELL_MAP; |
state change |
GRB10 | NCI_NATURE; |
state change |
INS | NCI_NATURE; |
state change |
INSR | NCI_NATURE; |
state change |
KIT | NCI_NATURE; |
state change |
KITLG | NCI_NATURE; |
state change |
LYN | CELL_MAP; |
state change |
PDGFB | NCI_NATURE; |
state change |
PDGFRB | NCI_NATURE; |
state change |
PTPN1 | NCI_NATURE; |
state change |
SHC1 | NCI_NATURE; |
state change |
SOS1 | NCI_NATURE; |