Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1869

Name

E2F1

Synonymous

E2F-1|RBAP1|RBBP3|RBP3;E2F transcription factor 1;E2F1;E2F transcription factor 1

Definition

PBR3|PRB-binding protein E2F-1|RBAP-1|RBBP-3|retinoblastoma-associated protein 1|retinoblastoma-binding protein 3|transcription factor E2F1

Position

20q11.2

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 HDAC1NCI_NATURE;

in same component

 KAT2BNCI_NATURE;

in same component

 NDNNCI_NATURE;

in same component

 NDNL2NCI_NATURE;

in same component

 RB1NCI_NATURE;

in same component

 RB1REACTOME;

in same component

 TFDP1REACTOME;

in same component

 TOPBP1NCI_NATURE;

interacts with

 ARID1BHPRD;

interacts with

 ARID3ABIOGRID;

interacts with

 ARID3AHPRD;

interacts with

 ASH2LBIOGRID;

interacts with

 ATAD2BIOGRID;

interacts with

 ATMBIOGRID;

interacts with

 ATMHPRD;

interacts with

 ATRBIOGRID;

interacts with

 ATRHPRD;

interacts with

 BRD2BIOGRID;

interacts with

 BRD2HPRD;

interacts with

 BTG3MINT;

interacts with

 CCNA1BIOGRID;

interacts with

 CCNA2BIOGRID;

interacts with

 CCNA2HPRD;

interacts with

 CDK2BIOGRID;

interacts with

 CDK2HPRD;

interacts with

 CDK3HPRD;

interacts with

 CDK7BIOGRID;

interacts with

 CDK7HPRD;

interacts with

 CDKN1ABIOGRID;

interacts with

 CDKN2AHPRD;

interacts with

 CDT1BIOGRID;

interacts with

 CEBPEHPRD;

interacts with

 CHEK2HPRD;

interacts with

 CREBBPBIOGRID;

interacts with

 CREBBPHPRD;

interacts with

 CTDP1HPRD;

interacts with

 CUL1BIOGRID;

interacts with

 CUL1HPRD;

interacts with

 DDB2HPRD;

interacts with

 DNMT1BIOGRID;

interacts with

 DNMT1HPRD;

interacts with

 E2F4BIOGRID;

interacts with

 E2F4HPRD;

interacts with

 E2F5HPRD;

interacts with

 E2F6HPRD;

interacts with

 FHL2BIOGRID;

interacts with

 GSK3BBIOGRID;

interacts with

 GSK3BHPRD;

interacts with

 GTF2H1BIOGRID;

interacts with

 GTF2H1HPRD;

interacts with

 HCFC1BIOGRID;

interacts with

 HDAC1BIOGRID;

interacts with

 HDAC3HPRD;

interacts with

 KAT2ABIOGRID;

interacts with

 KAT2BBIOGRID;

interacts with

 KAT5BIOGRID;

interacts with

 KDM1ABIOGRID;

interacts with

 KLF6BIOGRID;

interacts with

 LEF1BIOGRID;

interacts with

 MCPH1BIOGRID;

interacts with

 MCPH1MINT;

interacts with

 MDM2BIOGRID;

interacts with

 MDM2HPRD;

interacts with

 MDM4BIOGRID;

interacts with

 MDM4HPRD;

interacts with

 MGABIOGRID;

interacts with

 MNAT1HPRD;

interacts with

 MYBL2BIOGRID;

interacts with

 NCOA3HPRD;

interacts with

 NCOA6BIOGRID;

interacts with

 NCOA6HPRD;

interacts with

 NDNBIOGRID;

interacts with

 NDNHPRD;

interacts with

 NDNL2BIOGRID;

interacts with

 Nfkb1BIOGRID;

interacts with

 NFKB1BIOGRID;

interacts with

 NFKB1HPRD;

interacts with

 NPDC1BIOGRID;

interacts with

 NPDC1HPRD;

interacts with

 NRIP1BIOGRID;

interacts with

 PARP1HPRD;

interacts with

 PHBBIOGRID;

interacts with

 PHBHPRD;

interacts with

 PKIBBIOGRID;

interacts with

 PRDM2BIOGRID;

interacts with

 PRMT2HPRD;

interacts with

 PURABIOGRID;

interacts with

 PURAHPRD;

interacts with

 RB1BIOGRID;

interacts with

 RB1HPRD;

interacts with

 RB1INTACT;

interacts with

 RB1MINT;

interacts with

 RBBP4BIOGRID;

interacts with

 RBL1BIOGRID;

interacts with

 RBL1HPRD;

interacts with

 RBX1BIOGRID;

interacts with

 RING1BIOGRID;

interacts with

 RNF144ABIOGRID;

interacts with

 SERTAD2HPRD;

interacts with

 SETD7BIOGRID;

interacts with

 SIRT1BIOGRID;

interacts with

 SKP2BIOGRID;

interacts with

 SKP2HPRD;

interacts with

 Sp1BIOGRID;

interacts with

 SP1BIOGRID;

interacts with

 SP1HPRD;

interacts with

 SP2BIOGRID;

interacts with

 SP2HPRD;

interacts with

 SP3BIOGRID;

interacts with

 SP3HPRD;

interacts with

 SP4BIOGRID;

interacts with

 SP4HPRD;

interacts with

 SPIBBIOGRID;

interacts with

 STAT3HPRD;

interacts with

 TBPBIOGRID;

interacts with

 TEAD3BIOGRID;

interacts with

 TFDP1BIOGRID;

interacts with

 TFDP1HPRD;

interacts with

 TFDP2BIOGRID;

interacts with

 TFDP2HPRD;

interacts with

 TOPBP1BIOGRID;

interacts with

 TOPBP1MINT;

interacts with

 TP53BP1BIOGRID;

interacts with

 TP53BP1HPRD;

interacts with

 TRIM28BIOGRID;

interacts with

 TRIM36HPRD;

interacts with

 TRRAPBIOGRID;

interacts with

 TRRAPHPRD;

interacts with

 YWHAQBIOGRID;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 E2F1NCI_NATURE;

metabolic catalysis

 E2F4NCI_NATURE;

metabolic catalysis

 E2F4REACTOME;

metabolic catalysis

 E2F6NCI_NATURE;

metabolic catalysis

 HDAC1NCI_NATURE;

metabolic catalysis

 HDAC1REACTOME;

metabolic catalysis

 HES1NCI_NATURE;

metabolic catalysis

 KAT2ANCI_NATURE;

metabolic catalysis

 LIN37REACTOME;

metabolic catalysis

 LIN52REACTOME;

metabolic catalysis

 LIN54REACTOME;

metabolic catalysis

 LIN9REACTOME;

metabolic catalysis

 RBBP4REACTOME;

metabolic catalysis

 RBL1REACTOME;

metabolic catalysis

 RBL2REACTOME;

metabolic catalysis

 SIRT1NCI_NATURE;

metabolic catalysis

 SP1NCI_NATURE;

metabolic catalysis

 TFDP2NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 CDC25AREACTOME;

reacts with

 CDC6REACTOME;

reacts with

 CDK1REACTOME;

reacts with

 E2F1NCI_NATURE;

reacts with

 E2F1REACTOME;

reacts with

 HDAC1NCI_NATURE;

reacts with

 KAT2BNCI_NATURE;

reacts with

 MYBL2REACTOME;

reacts with

 NDNNCI_NATURE;

reacts with

 NDNL2NCI_NATURE;

reacts with

 NGFNCI_NATURE;

reacts with

 NGFRNCI_NATURE;

reacts with

 PCNAREACTOME;

reacts with

 RB1REACTOME;

reacts with

 RBL1REACTOME;

reacts with

 SORT1NCI_NATURE;

reacts with

 TFDP1REACTOME;

reacts with

 TOP2AREACTOME;

reacts with

 TOPBP1NCI_NATURE;

state change

 ATMNCI_NATURE;

state change

 RPS6KB1NCI_NATURE;

state change

 TRIM28NCI_NATURE;

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