Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

317

Name

APAF1

Synonymous

APAF-1|CED4;apoptotic peptidase activating factor 1;APAF1;apoptotic peptidase activating factor 1

Definition

apoptotic protease-activating factor 1

Position

12q23

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 ANP32AIMID;

in same component

 CASP9NCI_NATURE;

in same component

 CASP9REACTOME;

in same component

 COX5BIMID;

in same component

 CYCSREACTOME;

interacts with

 ACACAINTACT;

interacts with

 ANKRD11INTACT;

interacts with

 APIPBIOGRID;

interacts with

 APIPHPRD;

interacts with

 ARMC1INTACT;

interacts with

 ASXL1INTACT;

interacts with

 AVENBIOGRID;

interacts with

 AVENHPRD;

interacts with

 AVENMINT;

interacts with

 BAG3INTACT;

interacts with

 BAZ1BINTACT;

interacts with

 BAZ2BINTACT;

interacts with

 BCL2L10HPRD;

interacts with

 Bcl2l10MINT;

interacts with

 BCL2L1BIOGRID;

interacts with

 BCL2L1HPRD;

interacts with

 BDP1INTACT;

interacts with

 CASP3HPRD;

interacts with

 CASP3INTACT;

interacts with

 CASP3MINT;

interacts with

 CASP4BIOGRID;

interacts with

 CASP4HPRD;

interacts with

 CASP8BIOGRID;

interacts with

 CASP8HPRD;

interacts with

 CASP9BIOGRID;

interacts with

 CASP9HPRD;

interacts with

 CASP9INTACT;

interacts with

 CASP9MINT;

interacts with

 CYCSBIOGRID;

interacts with

 CYCSHPRD;

interacts with

 DHX30INTACT;

interacts with

 DNMT1INTACT;

interacts with

 ERBB4INTACT;

interacts with

 FANCCINTACT;

interacts with

 FEM1BHPRD;

interacts with

 GRHL2INTACT;

interacts with

 HIP1HPRD;

interacts with

 HSP90AA1BIOGRID;

interacts with

 HSPA4BIOGRID;

interacts with

 ITCHINTACT;

interacts with

 JAK1INTACT;

interacts with

 JAK2INTACT;

interacts with

 KAT2AINTACT;

interacts with

 LATS2INTACT;

interacts with

 LMO7INTACT;

interacts with

 MAP3K1INTACT;

interacts with

 MED1INTACT;

interacts with

 MLL5INTACT;

interacts with

 NCOR1INTACT;

interacts with

 NCOR2INTACT;

interacts with

 NLRP1BIOGRID;

interacts with

 NSD1INTACT;

interacts with

 PARP1INTACT;

interacts with

 PHKA1INTACT;

interacts with

 PIK3CGINTACT;

interacts with

 PKD1L3INTACT;

interacts with

 PPEF2INTACT;

interacts with

 PPP1CAHPRD;

interacts with

 RARAINTACT;

interacts with

 RSF1INTACT;

interacts with

 SETD2INTACT;

interacts with

 TAF5LINTACT;

interacts with

 TRIAP1HPRD;

interacts with

 TRIP11INTACT;

interacts with

 TSHZ1INTACT;

interacts with

 WDR7INTACT;

interacts with

 XIAPHPRD;

interacts with

 ZBTB40INTACT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 E2F1NCI_NATURE;

metabolic catalysis

 TP53NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 ANP32AIMID;

reacts with

 APAF1IMID;

reacts with

 APAF1REACTOME;

reacts with

 CASP9REACTOME;

reacts with

 COX5BIMID;

reacts with

 CYCSREACTOME;

state change

 APAF1REACTOME;

state change

 CASP9REACTOME;

state change

 CYCSREACTOME;

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