Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	5727
Name	PTCH1
Synonymous	BCNS\|HPE7\|NBCCS\|PTC\|PTC1\|PTCH\|PTCH11;patched 1;PTCH1;patched 1
Definition	PTCH protein +12b\|PTCH protein +4'\|PTCH protein -10\|PTCH protein -3,4,5\|protein patched homolog 1
Position	9q22.3
Gene Type	protein-coding
Gene Interactions:	Physical Interaction Metabolic Interaction Signaling Interaction

Interaction Type	Interactor	Data Source
Physical Interaction [Top]
in same component	DHH	NCI_NATURE;
in same component	IHH	NCI_NATURE;
in same component	SHH	NCI_NATURE;
interacts with	CCNB1	CELL_MAP;
interacts with	CDK1	CELL_MAP;
interacts with	DHH	CELL_MAP;
interacts with	IHH	CELL_MAP;
interacts with	Shh	CELL_MAP;
interacts with	SMO	BIOGRID;
interacts with	SMO	CELL_MAP;

Interaction Type	Interactor	Data Source
Metabolic Interaction [Top]
metabolic catalysis	GLI1	NCI_NATURE;
metabolic catalysis	IHH	NCI_NATURE;
metabolic catalysis	PTCH1	NCI_NATURE;

Interaction Type	Interactor	Data Source
Signaling Interaction [Top]
reacts with	DHH	NCI_NATURE;
reacts with	GPC3	NCI_NATURE;
reacts with	IHH	NCI_NATURE;
reacts with	PTCH1	NCI_NATURE;
reacts with	SHH	NCI_NATURE;

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