Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5728

Name

PTEN

Synonymous

10q23del|BZS|CWS1|DEC|GLM2|MHAM|MMAC1|PTEN1|TEP1;phosphatase and tensin homolog;PTEN;phosphatase and tensin homolog

Definition

MMAC1 phosphatase and tensin homolog deleted on chromosome 10|mitochondrial PTENalpha|mitochondrial phosphatase and tensin protein alpha|mutated in multiple advanced cancers 1|phosphatase and tensin-like protein|phosphatidylinositol 3,4,5-trisphosphate 3-

Position

10q23.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 PDGFBNCI_NATURE;

in same component

 PDGFRBNCI_NATURE;

interacts with

 AKT1HPRD;

interacts with

 ANAPC4INTACT;

interacts with

 ANAPC5INTACT;

interacts with

 ANAPC7INTACT;

interacts with

 ANGBIOGRID;

interacts with

 ANGHPRD;

interacts with

 ARBIOGRID;

interacts with

 ARCELL_MAP;

interacts with

 ARHPRD;

interacts with

 CAV1BIOGRID;

interacts with

 CAV1HPRD;

interacts with

 CAV1MINT;

interacts with

 CDC27INTACT;

interacts with

 CHGBBIOGRID;

interacts with

 CHGBHPRD;

interacts with

 CHGBMINT;

interacts with

 COPS6BIOGRID;

interacts with

 COPS6HPRD;

interacts with

 COPS6MINT;

interacts with

 CSNK2A1BIOGRID;

interacts with

 CSNK2A1HPRD;

interacts with

 CSNK2A2BIOGRID;

interacts with

 CSNK2A2HPRD;

interacts with

 DLG1HPRD;

interacts with

 ESR1BIOGRID;

interacts with

 HBA1BIOGRID;

interacts with

 HBA1HPRD;

interacts with

 HBA1MINT;

interacts with

 MAGI2HPRD;

interacts with

 MAGI3BIOGRID;

interacts with

 MAGI3HPRD;

interacts with

 MAGI3MINT;

interacts with

 MAST1HPRD;

interacts with

 MAST2HPRD;

interacts with

 MAST3HPRD;

interacts with

 MVPBIOGRID;

interacts with

 MVPHPRD;

interacts with

 NEDD4BIOGRID;

interacts with

 PDGFRBHPRD;

interacts with

 PDGFRBMINT;

interacts with

 PPP1CAHPRD;

interacts with

 PRDX1MINT;

interacts with

 PTK2BIOGRID;

interacts with

 PXNBIOGRID;

interacts with

 PXNHPRD;

interacts with

 SLC9A3R1HPRD;

interacts with

 SLC9A3R1MINT;

interacts with

 SLC9A3R2HPRD;

interacts with

 Slc9a3r2MINT;

interacts with

 SLC9A3R2MINT;

interacts with

 STK11HPRD;

interacts with

 TP53BIOGRID;

interacts with

 UBE2IBIOGRID;

interacts with

 UBE2IHPRD;

interacts with

 UBE2L3BIOGRID;

interacts with

 UBE2L3HPRD;

interacts with

 UTP14ABIOGRID;

interacts with

 UTP14AHPRD;

interacts with

 UTP14AMINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 JUNNCI_NATURE;

metabolic catalysis

 TP53NCI_NATURE;

sequential catalysis

 PTENHUMANCYC;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 PDGFBNCI_NATURE;

reacts with

 PDGFRBNCI_NATURE;

reacts with

 PTENNCI_NATURE;

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