Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

695

Name

BTK

Synonymous

AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA;Bruton agammaglobulinemia tyrosine kinase;BTK;Bruton agammaglobulinemia tyrosine kinase

Definition

B-cell progenitor kinase|agammaglobulinaemia tyrosine kinase|dominant-negative kinase-deficient Brutons tyrosine kinase|truncated Bruton agammaglobulinemia tyrosine kinase|tyrosine-protein kinase BTK|tyrosine-protein kinase BTK isoform (lacking exon 14)

Position

Xq21.33-q22

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 BLNKNCI_NATURE;

in same component

 CD72NCI_NATURE;

in same component

 CD79ANCI_NATURE;

in same component

 CD79BNCI_NATURE;

in same component

 FASNCI_NATURE;

in same component

 FASLGNCI_NATURE;

in same component

 LYNNCI_NATURE;

in same component

 PLCG2NCI_NATURE;

in same component

 SYKNCI_NATURE;

interacts with

 ACTA1INTACT;

interacts with

 ACTN1INTACT;

interacts with

 AFG3L2INTACT;

interacts with

 ARHGAP17BIOGRID;

interacts with

 ARHGAP17HPRD;

interacts with

 ARID3ABIOGRID;

interacts with

 ARID3AHPRD;

interacts with

 ARID3AMINT;

interacts with

 ATP5A1INTACT;

interacts with

 ATP5BINTACT;

interacts with

 BCL2L11BIOGRID;

interacts with

 BLNKBIOGRID;

interacts with

 BLNKHPRD;

interacts with

 BlnkMINT;

interacts with

 BLNKMINT;

interacts with

 BMXHPRD;

interacts with

 CAV1BIOGRID;

interacts with

 CAV1HPRD;

interacts with

 CBLBBIOGRID;

interacts with

 CBLBIOGRID;

interacts with

 CBLHPRD;

interacts with

 CD19HPRD;

interacts with

 CD19MINT;

interacts with

 CMTM3HPRD;

interacts with

 DAAM1MINT;

interacts with

 DAPP1HPRD;

interacts with

 DBN1INTACT;

interacts with

 DDX3XINTACT;

interacts with

 EEF1A2INTACT;

interacts with

 EWSR1BIOGRID;

interacts with

 FLNAINTACT;

interacts with

 FYNBIOGRID;

interacts with

 GAPDHINTACT;

interacts with

 GNAQBIOGRID;

interacts with

 GNAQHPRD;

interacts with

 GNG2HPRD;

interacts with

 GTF2IBIOGRID;

interacts with

 GTF2IHPRD;

interacts with

 GTF2IMINT;

interacts with

 HADHAINTACT;

interacts with

 HCKBIOGRID;

interacts with

 HCKHPRD;

interacts with

 HRNRINTACT;

interacts with

 IBTKBIOGRID;

interacts with

 IBTKHPRD;

interacts with

 IBTKMINT;

interacts with

 IGHMMINT;

interacts with

 IRAK1HPRD;

interacts with

 ITKHPRD;

interacts with

 JAK1BIOGRID;

interacts with

 JAK1HPRD;

interacts with

 KHDRBS1BIOGRID;

interacts with

 KHDRBS1HPRD;

interacts with

 KITHPRD;

interacts with

 KRT5INTACT;

interacts with

 LYNBIOGRID;

interacts with

 LYNHPRD;

interacts with

 MAPK1HPRD;

interacts with

 MED28MINT;

interacts with

 MYD88HPRD;

interacts with

 MYLK2INTACT;

interacts with

 NDUFS1INTACT;

interacts with

 PIK3AP1HPRD;

interacts with

 PIP4K2AHPRD;

interacts with

 PIP4K2BHPRD;

interacts with

 PIP5K1AHPRD;

interacts with

 PIP5K1BHPRD;

interacts with

 PIP5K1CHPRD;

interacts with

 PLCG2BIOGRID;

interacts with

 PLCG2HPRD;

interacts with

 POTEKPINTACT;

interacts with

 PRKCAHPRD;

interacts with

 PRKCBBIOGRID;

interacts with

 PRKCBHPRD;

interacts with

 PRKCEHPRD;

interacts with

 PRKCQHPRD;

interacts with

 PRKCZHPRD;

interacts with

 PRKD1BIOGRID;

interacts with

 PRKD1HPRD;

interacts with

 RELAHPRD;

interacts with

 RFTN1MINT;

interacts with

 RPS3INTACT;

interacts with

 RPS6KB1BIOGRID;

interacts with

 RPS6KB2BIOGRID;

interacts with

 SFPQINTACT;

interacts with

 SH2B2HPRD;

interacts with

 SH3BP5BIOGRID;

interacts with

 SH3BP5HPRD;

interacts with

 SPTA1INTACT;

interacts with

 STAT5AHPRD;

interacts with

 SYKHPRD;

interacts with

 TECHPRD;

interacts with

 TIRAPHPRD;

interacts with

 TLR6HPRD;

interacts with

 TLR8HPRD;

interacts with

 TLR9HPRD;

interacts with

 TNFRSF10AHPRD;

interacts with

 TUBA4AINTACT;

interacts with

 TUBB2CINTACT;

interacts with

 TWF1INTACT;

interacts with

 VAV1BIOGRID;

interacts with

 VAV1HPRD;

interacts with

 WASBIOGRID;

interacts with

 WASHPRD;

Metabolic Interaction   [Top]

There is no record for BTK

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 BLNKNCI_NATURE;

reacts with

 BTKNCI_NATURE;

reacts with

 CD72NCI_NATURE;

reacts with

 CD79ANCI_NATURE;

reacts with

 CD79BNCI_NATURE;

reacts with

 FADDNCI_NATURE;

reacts with

 FASNCI_NATURE;

reacts with

 FASLGNCI_NATURE;

reacts with

 LYNNCI_NATURE;

reacts with

 PLCG2NCI_NATURE;

reacts with

 PTPN6NCI_NATURE;

reacts with

 SYKNCI_NATURE;

state change

 EPONCI_NATURE;

state change

 EPORNCI_NATURE;

state change

 FCER1ANCI_NATURE;

state change

 FCER1GNCI_NATURE;

state change

 IBTKNCI_NATURE;

state change

 IGHENCI_NATURE;

state change

 INPP5DNCI_NATURE;

state change

 JAK2NCI_NATURE;

state change

 LYNNCI_NATURE;

state change

 MS4A2NCI_NATURE;

state change

 PIK3CANCI_NATURE;

state change

 PIK3R1NCI_NATURE;

state change

 SH3BP5NCI_NATURE;

state change

 SYKNCI_NATURE;

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