General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 7040 |
Name | TGFB1 |
Synonymous | CED|DPD1|LAP|TGFB|TGFbeta;transforming growth factor, beta 1;TGFB1;transforming growth factor, beta 1 |
Definition | TGF-beta-1|latency-associated peptide|prepro-transforming growth factor beta-1|transforming growth factor beta-1 |
Position | 19q13.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
ACVRL1 | NCI_NATURE; |
in same component |
CAV1 | NCI_NATURE; |
in same component |
CSNK2B | NCI_NATURE; |
in same component |
PPP1CA | NCI_NATURE; |
in same component |
SDC2 | NCI_NATURE; |
in same component |
TGFBR1 | NCI_NATURE; |
in same component |
TGFBR1 | REACTOME; |
in same component |
TGFBR2 | CELL_MAP; |
in same component |
TGFBR2 | NCI_NATURE; |
in same component |
TGFBR2 | REACTOME; |
in same component |
Tgfbr3 | CELL_MAP; |
in same component |
TGFBR3 | CELL_MAP; |
interacts with |
ACVRL1 | BIOGRID; |
interacts with |
Acvrl1 | CELL_MAP; |
interacts with |
ACVRL1 | HPRD; |
interacts with |
BGN | BIOGRID; |
interacts with |
BGN | HPRD; |
interacts with |
BMP2 | HPRD; |
interacts with |
BMP3 | HPRD; |
interacts with |
CCL3 | HPRD; |
interacts with |
COL2A1 | BIOGRID; |
interacts with |
COL2A1 | HPRD; |
interacts with |
CTCF | HPRD; |
interacts with |
CTGF | HPRD; |
interacts with |
DAXX | HPRD; |
interacts with |
DCN | BIOGRID; |
interacts with |
DIP2A | MINT; |
interacts with |
DPT | HPRD; |
interacts with |
EIF3I | BIOGRID; |
interacts with |
EIF3I | HPRD; |
interacts with |
ENG | HPRD; |
interacts with |
ENG | INTACT; |
interacts with |
FCN1 | BIOGRID; |
interacts with |
FCN1 | HPRD; |
interacts with |
FKBP1A | BIOGRID; |
interacts with |
FMOD | BIOGRID; |
interacts with |
FMOD | HPRD; |
interacts with |
FNTA | BIOGRID; |
interacts with |
FNTA | HPRD; |
interacts with |
FSTL1 | MINT; |
interacts with |
ITGAV | HPRD; |
interacts with |
ITGB6 | HPRD; |
interacts with |
ITGB8 | HPRD; |
interacts with |
LAMB1 | BIOGRID; |
interacts with |
LAMB1 | INTACT; |
interacts with |
LTBP1 | BIOGRID; |
interacts with |
LTBP4 | HPRD; |
interacts with |
MMP14 | HPRD; |
interacts with |
MMP2 | BIOGRID; |
interacts with |
MMP2 | HPRD; |
interacts with |
MMP9 | BIOGRID; |
interacts with |
PZP | HPRD; |
interacts with |
SDC2 | CELL_MAP; |
interacts with |
SDC2 | HPRD; |
interacts with |
SMAD2 | BIOGRID; |
interacts with |
SMAD4 | HPRD; |
interacts with |
SNIP1 | BIOGRID; |
interacts with |
SPARC | HPRD; |
interacts with |
TGFB2 | BIOGRID; |
interacts with |
TGFB2 | HPRD; |
interacts with |
TGFBR1 | BIOGRID; |
interacts with |
TGFBR1 | INTACT; |
interacts with |
TGFBR2 | BIOGRID; |
interacts with |
TGFBR2 | CELL_MAP; |
interacts with |
TGFBR2 | HPRD; |
interacts with |
TGFBR2 | INTACT; |
interacts with |
TGFBR2 | MINT; |
interacts with |
TGFBR3 | BIOGRID; |
interacts with |
Tgfbr3 | CELL_MAP; |
interacts with |
TGFBR3 | HPRD; |
interacts with |
TGFBR3 | INTACT; |
interacts with |
TGFBRAP1 | BIOGRID; |
interacts with |
THBS1 | BIOGRID; |
interacts with |
THBS1 | HPRD; |
interacts with |
VASN | BIOGRID; |
interacts with |
VASN | HPRD; |
interacts with |
VTN | BIOGRID; |
interacts with |
VTN | HPRD; |
interacts with |
YWHAE | BIOGRID; |
interacts with |
YWHAE | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
FOS | NCI_NATURE; |
metabolic catalysis |
JUN | NCI_NATURE; |
metabolic catalysis |
RPS6KB1 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ACVRL1 | NCI_NATURE; |
reacts with |
CAV1 | NCI_NATURE; |
reacts with |
CSNK2B | NCI_NATURE; |
reacts with |
FKBP1A | NCI_NATURE; |
reacts with |
PPP1CA | NCI_NATURE; |
reacts with |
SDC2 | NCI_NATURE; |
reacts with |
TGFB1 | NCI_NATURE; |
reacts with |
TGFB1 | REACTOME; |
reacts with |
TGFBR1 | NCI_NATURE; |
reacts with |
TGFBR1 | REACTOME; |
reacts with |
TGFBR2 | NCI_NATURE; |
reacts with |
TGFBR2 | REACTOME; |
state change |
PLG | NCI_NATURE; |
state change |
SMAD7 | NCI_NATURE; |
state change |
TGFB1 | REACTOME; |
state change |
TGFBR1 | REACTOME; |
state change |
TGFBR2 | REACTOME; |