Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7249

Name

TSC2

Synonymous

LAM|PPP1R160|TSC4;tuberous sclerosis 2;TSC2;tuberous sclerosis 2

Definition

protein phosphatase 1, regulatory subunit 160|tuberin|tuberous sclerosis 2 protein

Position

16p13.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 IKBKBNCI_NATURE;

in same component

 TSC1NCI_NATURE;

interacts with

 ACTA2MINT;

interacts with

 ACTBMINT;

interacts with

 ACTG1MINT;

interacts with

 ACTN2MINT;

interacts with

 ACTN3MINT;

interacts with

 AKT1BIOGRID;

interacts with

 AKT1HPRD;

interacts with

 AKT2HPRD;

interacts with

 AKT3HPRD;

interacts with

 ANKRD18AMINT;

interacts with

 ATP5A1MINT;

interacts with

 AXIN1BIOGRID;

interacts with

 AXIN1HPRD;

interacts with

 BANK1MINT;

interacts with

 CACNA1SMINT;

interacts with

 CALM1MINT;

interacts with

 CAV1BIOGRID;

interacts with

 CBLMINT;

interacts with

 CCND1BIOGRID;

interacts with

 CCND1HPRD;

interacts with

 CCND2BIOGRID;

interacts with

 CCND3BIOGRID;

interacts with

 CDKN1BBIOGRID;

interacts with

 CDKN1BHPRD;

interacts with

 CEP250MINT;

interacts with

 CUL4AHPRD;

interacts with

 DAPK1MINT;

interacts with

 DDB1HPRD;

interacts with

 DESMINT;

interacts with

 DOCK7HPRD;

interacts with

 ESR1HPRD;

interacts with

 FBXL6HPRD;

interacts with

 FBXW5BIOGRID;

interacts with

 FBXW5HPRD;

interacts with

 FOXO1BIOGRID;

interacts with

 GSK3BBIOGRID;

interacts with

 GSK3BHPRD;

interacts with

 H1F0MINT;

interacts with

 H2AFXMINT;

interacts with

 HIST1H1CMINT;

interacts with

 HIST1H1DMINT;

interacts with

 HIST1H1TMINT;

interacts with

 HIST1H2AGMINT;

interacts with

 HIST1H2BDMINT;

interacts with

 HNRNPA2B1MINT;

interacts with

 HNRNPCMINT;

interacts with

 KRT17MINT;

interacts with

 KRT18MINT;

interacts with

 KRT8MINT;

interacts with

 LMNAMINT;

interacts with

 MAPK1BIOGRID;

interacts with

 MAPK1HPRD;

interacts with

 MAPK3HPRD;

interacts with

 MAPKAPK2HPRD;

interacts with

 MYH11MINT;

interacts with

 MYH13MINT;

interacts with

 MYH2MINT;

interacts with

 MYH3MINT;

interacts with

 MYH7MINT;

interacts with

 MYH9MINT;

interacts with

 MYL12AMINT;

interacts with

 MYL3MINT;

interacts with

 MYLK2MINT;

interacts with

 NEK1HPRD;

interacts with

 PAMBIOGRID;

interacts with

 PAMHPRD;

interacts with

 PLK1BIOGRID;

interacts with

 PLK1HPRD;

interacts with

 PPP2CAHPRD;

interacts with

 PRKAA1BIOGRID;

interacts with

 PTK2BIOGRID;

interacts with

 RAB5ABIOGRID;

interacts with

 RAB5AHPRD;

interacts with

 RABEP1HPRD;

interacts with

 RALABIOGRID;

interacts with

 RALYMINT;

interacts with

 RAP1ABIOGRID;

interacts with

 RHEBBIOGRID;

interacts with

 RHEBHPRD;

interacts with

 RPS3MINT;

interacts with

 RPS6KA1BIOGRID;

interacts with

 RPS6KA1HPRD;

interacts with

 SFNHPRD;

interacts with

 SFNMINT;

interacts with

 SMAD2HPRD;

interacts with

 TBC1D7BIOGRID;

interacts with

 TBC1D7HPRD;

interacts with

 TGIF2LYMINT;

interacts with

 TPM1MINT;

interacts with

 TSC1BIOGRID;

interacts with

 TSC1MINT;

interacts with

 TTNMINT;

interacts with

 TUBB2AMINT;

interacts with

 UBE3ABIOGRID;

interacts with

 USP42MINT;

interacts with

 VASPMINT;

interacts with

 VIMMINT;

interacts with

 YWHABBIOGRID;

interacts with

 YWHABHPRD;

interacts with

 YWHABMINT;

interacts with

 YWHAEHPRD;

interacts with

 YWHAEMINT;

interacts with

 YWHAGHPRD;

interacts with

 YWHAGMINT;

interacts with

 YWHAHHPRD;

interacts with

 YWHAHMINT;

interacts with

 YWHAQBIOGRID;

interacts with

 YWHAQHPRD;

interacts with

 YWHAQMINT;

interacts with

 YWHAZBIOGRID;

interacts with

 YWHAZHPRD;

interacts with

 YWHAZMINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 MAXNCI_NATURE;

metabolic catalysis

 MYCNCI_NATURE;

metabolic catalysis

 TP53NCI_NATURE;

sequential catalysis

 TSC2IMID;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 DDIT4NCI_NATURE;

reacts with

 IKBKBNCI_NATURE;

reacts with

 TSC1NCI_NATURE;

reacts with

 TSC2NCI_NATURE;

state change

 AKT1NCI_NATURE;

state change

 GSK3BNCI_NATURE;

state change

 MAPKAPK2NCI_NATURE;

state change

 RPS6KA1NCI_NATURE;

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