General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 860 |
Name | RUNX2 |
Synonymous | AML3|CBF-alpha-1|CBFA1|CCD|CCD1|CLCD|OSF-2|OSF2|PEA2aA|PEBP2aA;runt-related transcription factor 2;RUNX2;runt-related transcription factor 2 |
Definition | PEA2-alpha A|PEBP2-alpha A|SL3-3 enhancer factor 1 alpha A subunit|SL3/AKV core-binding factor alpha A subunit|acute myeloid leukemia 3 protein|core-binding factor, runt domain, alpha subunit 1|oncogene AML-3|osteoblast-specific transcription factor 2|pol |
Position | 6p21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
Dvl2 | CELL_MAP; |
in same component |
HES1 | NCI_NATURE; |
in same component |
HEY2 | NCI_NATURE; |
in same component |
RB1 | NCI_NATURE; |
in same component |
SMAD4 | NCI_NATURE; |
interacts with |
AAT1 | INTACT; |
interacts with |
ABCA9 | INTACT; |
interacts with |
ABCB1 | INTACT; |
interacts with |
ABRA | INTACT; |
interacts with |
ACACB | INTACT; |
interacts with |
ACTC1 | INTACT; |
interacts with |
ADAMTS20 | INTACT; |
interacts with |
ADNP | INTACT; |
interacts with |
AGK | INTACT; |
interacts with |
AGPAT1 | INTACT; |
interacts with |
AHNAK2 | INTACT; |
interacts with |
AHNAK | INTACT; |
interacts with |
AIFM2 | INTACT; |
interacts with |
AJAP1 | INTACT; |
interacts with |
AKT1 | HPRD; |
interacts with |
ALPK3 | INTACT; |
interacts with |
ANLN | INTACT; |
interacts with |
AP4B1 | INTACT; |
interacts with |
ARFGAP1 | INTACT; |
interacts with |
ARG1 | INTACT; |
interacts with |
ARID4B | INTACT; |
interacts with |
ARID5B | INTACT; |
interacts with |
AR | CELL_MAP; |
interacts with |
AR | HPRD; |
interacts with |
ATM | INTACT; |
interacts with |
ATP5O | INTACT; |
interacts with |
ATP6V1D | INTACT; |
interacts with |
AXIN1 | CELL_MAP; |
interacts with |
AXIN1 | HPRD; |
interacts with |
BAHCC1 | INTACT; |
interacts with |
BCMO1 | INTACT; |
interacts with |
BMPR1A | BIOGRID; |
interacts with |
BPTF | INTACT; |
interacts with |
BRWD1 | INTACT; |
interacts with |
BUB1 | INTACT; |
interacts with |
C14orf43 | INTACT; |
interacts with |
C20orf160 | INTACT; |
interacts with |
C2orf16 | INTACT; |
interacts with |
C2orf29 | INTACT; |
interacts with |
C2orf89 | INTACT; |
interacts with |
C4A | INTACT; |
interacts with |
CALCOCO2 | INTACT; |
interacts with |
CALD1 | INTACT; |
interacts with |
CBFB | HPRD; |
interacts with |
CBFB | INTACT; |
interacts with |
CCNB1 | HPRD; |
interacts with |
CDC26 | INTACT; |
interacts with |
CDC42EP1 | INTACT; |
interacts with |
CDK4 | BIOGRID; |
interacts with |
CDK5RAP2 | INTACT; |
interacts with |
CDV3 | INTACT; |
interacts with |
CEBPB | HPRD; |
interacts with |
CENPV | INTACT; |
interacts with |
CEP170 | INTACT; |
interacts with |
CEP55 | INTACT; |
interacts with |
CFL1 | INTACT; |
interacts with |
CHAF1B | INTACT; |
interacts with |
CKAP4 | INTACT; |
interacts with |
CLEC11A | INTACT; |
interacts with |
CLSTN1 | INTACT; |
interacts with |
CNOT4 | INTACT; |
interacts with |
CNTN5 | INTACT; |
interacts with |
CPSF2 | INTACT; |
interacts with |
CREBBP | BIOGRID; |
interacts with |
CROCC | INTACT; |
interacts with |
CSF1 | INTACT; |
interacts with |
CTBP1 | INTACT; |
interacts with |
CTR9 | INTACT; |
interacts with |
CYBA | INTACT; |
interacts with |
CYP2U1 | INTACT; |
interacts with |
DACT1 | INTACT; |
interacts with |
DDX24 | INTACT; |
interacts with |
DDX47 | INTACT; |
interacts with |
DDX51 | INTACT; |
interacts with |
DENND3 | INTACT; |
interacts with |
DHX58 | INTACT; |
interacts with |
DIP2B | INTACT; |
interacts with |
DIRAS2 | INTACT; |
interacts with |
DNAJB12 | INTACT; |
interacts with |
DPM1 | INTACT; |
interacts with |
DUSP15 | INTACT; |
interacts with |
DVL2 | CELL_MAP; |
interacts with |
DVL2 | HPRD; |
interacts with |
DYNC1LI1 | INTACT; |
interacts with |
DYNLRB1 | INTACT; |
interacts with |
EHHADH | INTACT; |
interacts with |
ELFN1 | INTACT; |
interacts with |
EP300 | BIOGRID; |
interacts with |
EP300 | HPRD; |
interacts with |
EP400 | INTACT; |
interacts with |
EPC1 | INTACT; |
interacts with |
ERBB2IP | INTACT; |
interacts with |
ERP44 | INTACT; |
interacts with |
ETS1 | BIOGRID; |
interacts with |
ETS1 | HPRD; |
interacts with |
ETV3 | INTACT; |
interacts with |
ETV6 | INTACT; |
interacts with |
EXOSC1 | INTACT; |
interacts with |
FAF2 | INTACT; |
interacts with |
FAM116B | INTACT; |
interacts with |
FAM117B | INTACT; |
interacts with |
FANCM | INTACT; |
interacts with |
FASTKD1 | INTACT; |
interacts with |
FERMT3 | INTACT; |
interacts with |
FN1 | INTACT; |
interacts with |
FOSL2 | INTACT; |
interacts with |
FOS | BIOGRID; |
interacts with |
FOXC2 | INTACT; |
interacts with |
FRMD6 | INTACT; |
interacts with |
FRMPD4 | INTACT; |
interacts with |
FZR1 | INTACT; |
interacts with |
GABRR1 | INTACT; |
interacts with |
GFPT1 | INTACT; |
interacts with |
GLTSCR1 | INTACT; |
interacts with |
GPR158 | INTACT; |
interacts with |
GSK3B | INTACT; |
interacts with |
GTF3C4 | INTACT; |
interacts with |
HADHB | INTACT; |
interacts with |
HCFC2 | INTACT; |
interacts with |
HDAC1 | BIOGRID; |
interacts with |
HDAC3 | BIOGRID; |
interacts with |
HDAC3 | HPRD; |
interacts with |
HDAC4 | BIOGRID; |
interacts with |
HDAC4 | HPRD; |
interacts with |
HDAC5 | BIOGRID; |
interacts with |
HDAC6 | BIOGRID; |
interacts with |
HDAC6 | HPRD; |
interacts with |
HDAC7 | BIOGRID; |
interacts with |
HES1 | BIOGRID; |
interacts with |
HIRA | INTACT; |
interacts with |
HIST1H1A | INTACT; |
interacts with |
HIST1H2AB | INTACT; |
interacts with |
HIST1H2BM | INTACT; |
interacts with |
HK1 | INTACT; |
interacts with |
HNRNPC | INTACT; |
interacts with |
HOXA10 | INTACT; |
interacts with |
HOXB5 | INTACT; |
interacts with |
HSD17B4 | INTACT; |
interacts with |
HSPB1 | INTACT; |
interacts with |
IGF2BP2 | INTACT; |
interacts with |
IL16 | INTACT; |
interacts with |
IL1B | INTACT; |
interacts with |
IMMT | INTACT; |
interacts with |
INSM1 | INTACT; |
interacts with |
JUN | BIOGRID; |
interacts with |
JUN | HPRD; |
interacts with |
JUN | INTACT; |
interacts with |
KALRN | INTACT; |
interacts with |
KANK2 | INTACT; |
interacts with |
KARS | INTACT; |
interacts with |
KAT2B | BIOGRID; |
interacts with |
KCNG3 | INTACT; |
interacts with |
KIAA0319 | INTACT; |
interacts with |
KIAA0922 | INTACT; |
interacts with |
KIAA2026 | INTACT; |
interacts with |
KIF12 | INTACT; |
interacts with |
KIF20B | INTACT; |
interacts with |
LBX2 | INTACT; |
interacts with |
LCN12 | INTACT; |
interacts with |
LGALS1 | INTACT; |
interacts with |
LGALS7 | INTACT; |
interacts with |
LIMS1 | INTACT; |
interacts with |
LOX | INTACT; |
interacts with |
LRP1B | INTACT; |
interacts with |
MAGEB10 | INTACT; |
interacts with |
MAGI1 | INTACT; |
interacts with |
MAP1A | INTACT; |
interacts with |
MAP3K1 | INTACT; |
interacts with |
MAP3K4 | CELL_MAP; |
interacts with |
MAP3K4 | HPRD; |
interacts with |
MAP3K5 | INTACT; |
interacts with |
MAP3K7 | INTACT; |
interacts with |
MAP7D1 | INTACT; |
interacts with |
MAST4 | INTACT; |
interacts with |
MATN4 | INTACT; |
interacts with |
MAX | INTACT; |
interacts with |
MCF2L2 | INTACT; |
interacts with |
MCM4 | INTACT; |
interacts with |
MCTP2 | INTACT; |
interacts with |
MED12L | INTACT; |
interacts with |
MFHAS1 | INTACT; |
interacts with |
MIB1 | INTACT; |
interacts with |
MLL | INTACT; |
interacts with |
MRGBP | INTACT; |
interacts with |
MRPL14 | INTACT; |
interacts with |
MSX2 | BIOGRID; |
interacts with |
MSX2 | HPRD; |
interacts with |
MTRF1 | INTACT; |
interacts with |
MYC | INTACT; |
interacts with |
MYO18A | INTACT; |
interacts with |
MYO1D | INTACT; |
interacts with |
MYST4 | BIOGRID; |
interacts with |
MYST4 | HPRD; |
interacts with |
NAIP | INTACT; |
interacts with |
NAV3 | INTACT; |
interacts with |
NCOR1 | INTACT; |
interacts with |
NCOR2 | INTACT; |
interacts with |
NFIL3 | INTACT; |
interacts with |
NPR1 | INTACT; |
interacts with |
NPTX2 | INTACT; |
interacts with |
NR0B2 | BIOGRID; |
interacts with |
NRD1 | INTACT; |
interacts with |
NUP98 | INTACT; |
interacts with |
OBSCN | INTACT; |
interacts with |
ODZ2 | INTACT; |
interacts with |
OPHN1 | INTACT; |
interacts with |
OTUD4 | INTACT; |
interacts with |
PADI2 | INTACT; |
interacts with |
PALD | INTACT; |
interacts with |
PCBP2 | INTACT; |
interacts with |
PDHA2 | INTACT; |
interacts with |
PDLIM4 | INTACT; |
interacts with |
PDS5B | INTACT; |
interacts with |
PFDN2 | INTACT; |
interacts with |
PGD | INTACT; |
interacts with |
PHF6 | INTACT; |
interacts with |
PITX2 | INTACT; |
interacts with |
PKM2 | INTACT; |
interacts with |
PLA2G4A | INTACT; |
interacts with |
PLEKHH1 | INTACT; |
interacts with |
PLOD2 | INTACT; |
interacts with |
POLG | INTACT; |
interacts with |
POLR3A | INTACT; |
interacts with |
POP4 | INTACT; |
interacts with |
PPA2 | INTACT; |
interacts with |
PPIP5K2 | INTACT; |
interacts with |
PPP2R3B | INTACT; |
interacts with |
PREX2 | INTACT; |
interacts with |
PRG4 | INTACT; |
interacts with |
PRKAR1B | INTACT; |
interacts with |
PRKCDBP | INTACT; |
interacts with |
PRKCD | HPRD; |
interacts with |
PRR11 | INTACT; |
interacts with |
PRRC2A | INTACT; |
interacts with |
PSMA3 | INTACT; |
interacts with |
PSMC1 | INTACT; |
interacts with |
PSMD2 | INTACT; |
interacts with |
PTBP1 | INTACT; |
interacts with |
QPCTL | INTACT; |
interacts with |
RAB11FIP5 | INTACT; |
interacts with |
RAC1 | CELL_MAP; |
interacts with |
RAD50 | INTACT; |
interacts with |
RAG1 | INTACT; |
interacts with |
RALGAPA1 | INTACT; |
interacts with |
RB1 | HPRD; |
interacts with |
RBFA | INTACT; |
interacts with |
RBFOX2 | INTACT; |
interacts with |
RBM10 | INTACT; |
interacts with |
RBM39 | INTACT; |
interacts with |
RFX7 | INTACT; |
interacts with |
RIMS2 | INTACT; |
interacts with |
RPL26L1 | INTACT; |
interacts with |
RPP30 | INTACT; |
interacts with |
RPRD2 | INTACT; |
interacts with |
RPS21 | INTACT; |
interacts with |
RPS27L | INTACT; |
interacts with |
RPS2 | INTACT; |
interacts with |
RRM1 | INTACT; |
interacts with |
RRP1B | INTACT; |
interacts with |
SACS | INTACT; |
interacts with |
SAMD9L | INTACT; |
interacts with |
SBNO2 | INTACT; |
interacts with |
SDF4 | INTACT; |
interacts with |
SDHA | INTACT; |
interacts with |
SEC11C | INTACT; |
interacts with |
SERPINH1 | INTACT; |
interacts with |
SETX | INTACT; |
interacts with |
SGOL2 | INTACT; |
interacts with |
SH3RF1 | INTACT; |
interacts with |
SHANK2 | INTACT; |
interacts with |
SHE | INTACT; |
interacts with |
SIPA1L3 | INTACT; |
interacts with |
SLC25A10 | INTACT; |
interacts with |
SMAD1 | BIOGRID; |
interacts with |
SMAD2 | BIOGRID; |
interacts with |
SMAD2 | CELL_MAP; |
interacts with |
SMAD2 | HPRD; |
interacts with |
SMAD5 | BIOGRID; |
interacts with |
SMAD6 | HPRD; |
interacts with |
SMARCA5 | INTACT; |
interacts with |
SMC6 | INTACT; |
interacts with |
SMTN | INTACT; |
interacts with |
SMYD4 | INTACT; |
interacts with |
SNX19 | INTACT; |
interacts with |
SQRDL | INTACT; |
interacts with |
ST6GALNAC6 | INTACT; |
interacts with |
STUB1 | BIOGRID; |
interacts with |
SUCLG1 | INTACT; |
interacts with |
SUCLG2 | INTACT; |
interacts with |
SYNE1 | INTACT; |
interacts with |
TAF1A | HPRD; |
interacts with |
TAF2 | INTACT; |
interacts with |
TBL2 | INTACT; |
interacts with |
TDG | INTACT; |
interacts with |
TENC1 | INTACT; |
interacts with |
TEX2 | INTACT; |
interacts with |
THOC4 | BIOGRID; |
interacts with |
TLE1 | BIOGRID; |
interacts with |
TMPRSS11A | INTACT; |
interacts with |
TNPO1 | INTACT; |
interacts with |
TNR | INTACT; |
interacts with |
TPH1 | INTACT; |
interacts with |
TPP1 | INTACT; |
interacts with |
TRAK1 | INTACT; |
interacts with |
TRAP1 | INTACT; |
interacts with |
TRRAP | INTACT; |
interacts with |
TUBA4A | INTACT; |
interacts with |
TUBB3 | INTACT; |
interacts with |
TUBB6 | INTACT; |
interacts with |
TUFM | INTACT; |
interacts with |
TXN | INTACT; |
interacts with |
UBA1 | INTACT; |
interacts with |
UBTF | HPRD; |
interacts with |
UBTF | INTACT; |
interacts with |
UQCRFS1 | INTACT; |
interacts with |
USP10 | INTACT; |
interacts with |
USP36 | INTACT; |
interacts with |
USP48 | INTACT; |
interacts with |
WDFY3 | INTACT; |
interacts with |
WIPF1 | INTACT; |
interacts with |
XKRX | INTACT; |
interacts with |
XRCC5 | BIOGRID; |
interacts with |
XRCC5 | HPRD; |
interacts with |
XRCC6 | BIOGRID; |
interacts with |
XRCC6 | HPRD; |
interacts with |
XYLT1 | INTACT; |
interacts with |
YAF2 | INTACT; |
interacts with |
YAP1 | BIOGRID; |
interacts with |
YAP1 | HPRD; |
interacts with |
ZC3H18 | INTACT; |
interacts with |
ZC3H7B | INTACT; |
interacts with |
ZFHX3 | INTACT; |
interacts with |
ZFP106 | INTACT; |
interacts with |
ZNF238 | INTACT; |
interacts with |
ZNF354B | INTACT; |
interacts with |
ZNF541 | INTACT; |
interacts with |
ZNF586 | INTACT; |
interacts with |
ZNF703 | INTACT; |
interacts with |
ZNF740 | INTACT; |
interacts with |
ZZEF1 | INTACT; |
Metabolic Interaction [Top] | ||
There is no record for RUNX2 |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
HES1 | NCI_NATURE; |
reacts with |
HEY2 | NCI_NATURE; |
reacts with |
RB1 | NCI_NATURE; |
reacts with |
RUNX2 | NCI_NATURE; |
reacts with |
SMAD4 | NCI_NATURE; |