Entrez Gene

Basic Information
Gene ID	860
Name	RUNX2
Synonymous	AML3\|CBF-alpha-1\|CBFA1\|CCD\|CCD1\|CLCD\|OSF-2\|OSF2\|PEA2aA\|PEBP2aA;runt-related transcription factor 2;RUNX2;runt-related transcription factor 2
Definition	PEA2-alpha A\|PEBP2-alpha A\|SL3-3 enhancer factor 1 alpha A subunit\|SL3/AKV core-binding factor alpha A subunit\|acute myeloid leukemia 3 protein\|core-binding factor, runt domain, alpha subunit 1\|oncogene AML-3\|osteoblast-specific transcription factor 2\|pol
Position	6p21
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
AML3(h) --> MPO(m) (DNA binding).
AML3(h) --> MMP13(h) (DNA binding).
AML3(h) --> SOST(h) (DNA binding).
AML3(h) --> ESR1(h) (DNA binding).
AML3(h) --> CLC(h) (DNA binding).
AML3(h) --> GNAS(h) (DNA binding).
AML3(h) --/ TERT(h) (DNA binding; transrepression).
AML3(h) + HDAC3(m.s.) <==> HDAC3(m.s.):AML3(h) (binding)
AML3(h) + CBP(m.s.) <==> CBP(m.s.):AML3(h) (binding)
AML3(h) --> BGLAP(h) (DNA binding).
AML3(h) --> FGFR2(h) (DNA binding).
AML3(h) --> RUNX2(h) (DNA binding).
AML3(h) --> TNFRSF11B(h) (DNA binding; transactivation).
AML3(h) --> Ambn(m) (DNA binding).
AML3(h) --> COL10A1(h) (transactivation)
AML3(h) --> Bglap(r) (DNA binding).
AML3(h) --> IBSP(h) (DNA binding).
AML3(h) --> IgH(m) (DNA binding).
AML3(h) --> Bglap2(m) (DNA binding).
RUNX2(h) --> AML3(h) (expression).
RUNX2(h) --> AML3-isoform2(h) (expression).
HDAC4(h) + AML3-isoform1(h) <==> HDAC4(h):AML3-isoform1(h) (binding)
RUNX2(h) --> AML3-isoform1(h) (expression).
RUNX2(h) --> AML3-isoform3(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for RUNX2