General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 8795 |
Name | TNFRSF10B |
Synonymous | CD262|DR5|KILLER|KILLER/DR5|TRAIL-R2|TRAILR2|TRICK2|TRICK2A|TRICK2B|TRICKB|ZTNFR9;tumor necrosis factor receptor superfamily, member 10b;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b |
Definition | Fas-like protein|TNF receptor superfamily member 10b|TNF-related apoptosis-inducing ligand receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|d |
Position | 8p22-p21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
CASP10 | REACTOME; |
in same component |
CASP8 | REACTOME; |
in same component |
FADD | NCI_NATURE; |
in same component |
FADD | REACTOME; |
in same component |
RIPK1 | NCI_NATURE; |
in same component |
TNFSF10 | NCI_NATURE; |
in same component |
TNFSF10 | REACTOME; |
in same component |
TRADD | NCI_NATURE; |
in same component |
TRAF2 | NCI_NATURE; |
interacts with |
ARHGDIA | BIOGRID; |
interacts with |
BID | BIOGRID; |
interacts with |
CASP10 | BIOGRID; |
interacts with |
CASP10 | HPRD; |
interacts with |
CASP8 | BIOGRID; |
interacts with |
CASP8 | HPRD; |
interacts with |
CBL | BIOGRID; |
interacts with |
CFLAR | BIOGRID; |
interacts with |
CFLAR | HPRD; |
interacts with |
EZR | BIOGRID; |
interacts with |
FADD | BIOGRID; |
interacts with |
FADD | HPRD; |
interacts with |
FADD | MINT; |
interacts with |
FASLG | BIOGRID; |
interacts with |
FAS | BIOGRID; |
interacts with |
MADD | HPRD; |
interacts with |
MAPK8 | BIOGRID; |
interacts with |
MSN | BIOGRID; |
interacts with |
RHOA | BIOGRID; |
interacts with |
RIPK1 | BIOGRID; |
interacts with |
RIPK1 | HPRD; |
interacts with |
TIMM50 | BIOGRID; |
interacts with |
TNFRSF10A | HPRD; |
interacts with |
TNFRSF10D | HPRD; |
interacts with |
TNFRSF1A | BIOGRID; |
interacts with |
TNFSF10 | BIOGRID; |
interacts with |
TNFSF10 | HPRD; |
interacts with |
TNFSF10 | MINT; |
interacts with |
TRADD | BIOGRID; |
interacts with |
TRADD | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
TP53 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
CASP10 | REACTOME; |
reacts with |
CASP8 | REACTOME; |
reacts with |
FADD | NCI_NATURE; |
reacts with |
FADD | REACTOME; |
reacts with |
RIPK1 | NCI_NATURE; |
reacts with |
TNFRSF10B | NCI_NATURE; |
reacts with |
TNFRSF10B | REACTOME; |
reacts with |
TNFSF10 | NCI_NATURE; |
reacts with |
TNFSF10 | REACTOME; |
reacts with |
TRADD | NCI_NATURE; |
reacts with |
TRAF2 | NCI_NATURE; |
state change |
CFLAR | REACTOME; |