General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 920 |
Name | CD4 |
Synonymous | CD4mut;CD4 molecule;CD4;CD4 molecule |
Definition | CD4 antigen (p55)|CD4 receptor|T-cell surface antigen T4/Leu-3|T-cell surface glycoprotein CD4 |
Position | 12p13.31 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
AP2B1 | REACTOME; |
in same component |
AP2M1 | REACTOME; |
in same component |
AP2S1 | REACTOME; |
in same component |
ATP6V1H | REACTOME; |
in same component |
BTRC | REACTOME; |
in same component |
CBL | NCI_NATURE; |
in same component |
CD247 | NCI_NATURE; |
in same component |
CD3D | NCI_NATURE; |
in same component |
CD3D | REACTOME; |
in same component |
CD3E | NCI_NATURE; |
in same component |
CD3E | REACTOME; |
in same component |
CD3G | NCI_NATURE; |
in same component |
CD3G | REACTOME; |
in same component |
CLTA | NCI_NATURE; |
in same component |
CLTB | NCI_NATURE; |
in same component |
COPA | NCI_NATURE; |
in same component |
FYN | NCI_NATURE; |
in same component |
HLA-DRA | NCI_NATURE; |
in same component |
HLA-DRB1 | NCI_NATURE; |
in same component |
LCK | NCI_NATURE; |
in same component |
LCK | REACTOME; |
in same component |
PPIA | REACTOME; |
in same component |
SH3BP2 | NCI_NATURE; |
in same component |
SKP1 | REACTOME; |
in same component |
SLA2 | NCI_NATURE; |
in same component |
ZAP70 | NCI_NATURE; |
in same component |
ZAP70 | REACTOME; |
interacts with |
BTRC | BIOGRID; |
interacts with |
CCR5 | BIOGRID; |
interacts with |
CCR5 | HPRD; |
interacts with |
CD28 | HPRD; |
interacts with |
CD2 | HPRD; |
interacts with |
CD38 | HPRD; |
interacts with |
CD44 | HPRD; |
interacts with |
CD53 | HPRD; |
interacts with |
CD5 | HPRD; |
interacts with |
CD81 | BIOGRID; |
interacts with |
CD82 | BIOGRID; |
interacts with |
CD82 | HPRD; |
interacts with |
CTSD | HPRD; |
interacts with |
CXCL12 | HPRD; |
interacts with |
CXCR4 | BIOGRID; |
interacts with |
CXCR4 | HPRD; |
interacts with |
DPP4 | HPRD; |
interacts with |
EPS15 | BIOGRID; |
interacts with |
FCGR3A | HPRD; |
interacts with |
HLA-DPA1 | HPRD; |
interacts with |
HLA-DQA2 | HPRD; |
interacts with |
HLA-DQB1 | HPRD; |
interacts with |
HRD3 | MINT; |
interacts with |
IL16 | BIOGRID; |
interacts with |
IL16 | HPRD; |
interacts with |
IL2RA | HPRD; |
interacts with |
KCNAB2 | BIOGRID; |
interacts with |
KCNAB2 | HPRD; |
interacts with |
LAT | HPRD; |
interacts with |
LCK | BIOGRID; |
interacts with |
LCK | HPRD; |
interacts with |
LCK | MINT; |
interacts with |
LGALS1 | BIOGRID; |
interacts with |
LGALS1 | HPRD; |
interacts with |
MAPK14 | BIOGRID; |
interacts with |
MARCH4 | HPRD; |
interacts with |
NR3C1 | HPRD; |
interacts with |
NR3C1 | MINT; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PIP | BIOGRID; |
interacts with |
PIP | HPRD; |
interacts with |
PTPRC | BIOGRID; |
interacts with |
PTPRC | HPRD; |
interacts with |
SELL | HPRD; |
interacts with |
SPG21 | BIOGRID; |
interacts with |
SPG21 | HPRD; |
interacts with |
SYK | BIOGRID; |
interacts with |
TFRC | HPRD; |
interacts with |
TNFRSF10A | HPRD; |
interacts with |
UNC119 | BIOGRID; |
interacts with |
UNC119 | HPRD; |
interacts with |
ZAP70 | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
HES1 | NCI_NATURE; |
metabolic catalysis |
IL12B | NCI_NATURE; |
metabolic catalysis |
IL12RB1 | NCI_NATURE; |
metabolic catalysis |
IL23A | NCI_NATURE; |
metabolic catalysis |
IL23R | NCI_NATURE; |
metabolic catalysis |
JAK2 | NCI_NATURE; |
metabolic catalysis |
MYB | NCI_NATURE; |
metabolic catalysis |
TYK2 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
AP2A1 | NCI_NATURE; |
reacts with |
AP2B1 | REACTOME; |
reacts with |
AP2M1 | NCI_NATURE; |
reacts with |
AP2M1 | REACTOME; |
reacts with |
AP2S1 | REACTOME; |
reacts with |
ATP6V1H | REACTOME; |
reacts with |
BTRC | REACTOME; |
reacts with |
CBL | NCI_NATURE; |
reacts with |
CD247 | NCI_NATURE; |
reacts with |
CD3D | NCI_NATURE; |
reacts with |
CD3D | REACTOME; |
reacts with |
CD3E | NCI_NATURE; |
reacts with |
CD3E | REACTOME; |
reacts with |
CD3G | NCI_NATURE; |
reacts with |
CD3G | REACTOME; |
reacts with |
CD4 | NCI_NATURE; |
reacts with |
CD4 | REACTOME; |
reacts with |
CLTA | NCI_NATURE; |
reacts with |
CLTB | NCI_NATURE; |
reacts with |
COPA | NCI_NATURE; |
reacts with |
FYN | NCI_NATURE; |
reacts with |
HLA-DRA | NCI_NATURE; |
reacts with |
HLA-DRB1 | NCI_NATURE; |
reacts with |
LCK | NCI_NATURE; |
reacts with |
LCK | REACTOME; |
reacts with |
PPIA | REACTOME; |
reacts with |
SH3BP2 | NCI_NATURE; |
reacts with |
SKP1 | REACTOME; |
reacts with |
SLA2 | NCI_NATURE; |
reacts with |
ZAP70 | NCI_NATURE; |
reacts with |
ZAP70 | REACTOME; |
state change |
BTRC | REACTOME; |
state change |
CD28 | NCI_NATURE; |
state change |
CD3D | REACTOME; |
state change |
CD3E | REACTOME; |
state change |
CD3G | REACTOME; |
state change |
CD4 | REACTOME; |
state change |
CSK | REACTOME; |
state change |
GNG2 | NCI_NATURE; |
state change |
LCK | REACTOME; |
state change |
PAG1 | REACTOME; |
state change |
PDCD1 | REACTOME; |
state change |
PTPN6 | NCI_NATURE; |
state change |
PTPRC | REACTOME; |
state change |
RGS1 | NCI_NATURE; |
state change |
SKP1 | REACTOME; |
state change |
ZAP70 | REACTOME; |