Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

9656

Name

MDC1

Synonymous

NFBD1;mediator of DNA-damage checkpoint 1;MDC1;mediator of DNA-damage checkpoint 1

Definition

homologue to Drosophila photoreceptor protein calphotin|mediator of DNA damage checkpoint 1|mediator of DNA damage checkpoint protein 1|nuclear factor with BRCT domains 1

Position

6p21.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 ATMNCI_NATURE;

in same component

 ATMREACTOME;

in same component

 BRCA1NCI_NATURE;

in same component

 BRCA1REACTOME;

in same component

 FAM175ANCI_NATURE;

in same component

 H2AFXNCI_NATURE;

in same component

 H2AFXREACTOME;

in same component

 MRE11ANCI_NATURE;

in same component

 NBNNCI_NATURE;

in same component

 RAD50NCI_NATURE;

in same component

 RNF8NCI_NATURE;

in same component

 TP53BP1NCI_NATURE;

in same component

 TP53BP1REACTOME;

in same component

 UIMC1NCI_NATURE;

interacts with

 ANAPC1BIOGRID;

interacts with

 ANAPC5BIOGRID;

interacts with

 ATMBIOGRID;

interacts with

 ATMHPRD;

interacts with

 BANF1BIOGRID;

interacts with

 BARD1HPRD;

interacts with

 BIRC5BIOGRID;

interacts with

 BRCA1BIOGRID;

interacts with

 CDC16BIOGRID;

interacts with

 CDC27BIOGRID;

interacts with

 CENPC1BIOGRID;

interacts with

 CHEK2BIOGRID;

interacts with

 CHEK2HPRD;

interacts with

 CREBBPHPRD;

interacts with

 CSNK2A1MINT;

interacts with

 EP300HPRD;

interacts with

 FANCD2HPRD;

interacts with

 GATA4BIOGRID;

interacts with

 H2AFXBIOGRID;

interacts with

 H2AFXHPRD;

interacts with

 H2AFXMINT;

interacts with

 HDAC10BIOGRID;

interacts with

 HDAC8BIOGRID;

interacts with

 MCPH1BIOGRID;

interacts with

 MDM2BIOGRID;

interacts with

 MRE11ABIOGRID;

interacts with

 MRE11AHPRD;

interacts with

 MRE11AMINT;

interacts with

 NBNBIOGRID;

interacts with

 NBNHPRD;

interacts with

 NBNMINT;

interacts with

 POLR2ABIOGRID;

interacts with

 PRKDCHPRD;

interacts with

 RAD50BIOGRID;

interacts with

 RAD50HPRD;

interacts with

 RAD50MINT;

interacts with

 RAD51BIOGRID;

interacts with

 RNF8BIOGRID;

interacts with

 RNF8HPRD;

interacts with

 SMC1AHPRD;

interacts with

 TP53BP1BIOGRID;

interacts with

 TP53BP1HPRD;

interacts with

 TP53BIOGRID;

interacts with

 UIMC1BIOGRID;

interacts with

 USP28BIOGRID;

interacts with

 USP28HPRD;

interacts with

 WRNBIOGRID;

interacts with

 XRCC5HPRD;

Metabolic Interaction   [Top]

There is no record for MDC1

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 ATMNCI_NATURE;

reacts with

 ATMREACTOME;

reacts with

 BRCA1NCI_NATURE;

reacts with

 BRCA1REACTOME;

reacts with

 CTBP1NCI_NATURE;

reacts with

 FAM175ANCI_NATURE;

reacts with

 H2AFXNCI_NATURE;

reacts with

 H2AFXREACTOME;

reacts with

 MDC1NCI_NATURE;

reacts with

 MDC1REACTOME;

reacts with

 MRE11ANCI_NATURE;

reacts with

 NBNNCI_NATURE;

reacts with

 RAD50NCI_NATURE;

reacts with

 RBBP8NCI_NATURE;

reacts with

 RNF8NCI_NATURE;

reacts with

 TP53BP1NCI_NATURE;

reacts with

 TP53BP1REACTOME;

reacts with

 UIMC1NCI_NATURE;

state change

 H2AFXREACTOME;

state change

 MDC1REACTOME;

state change

 UBE2NNCI_NATURE;

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