| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 134111 |
Name | UBE2QL1 |
Synonymous | ubiquitin-conjugating enzyme E2Q family-like 1;UBE2QL1;ubiquitin-conjugating enzyme E2Q family-like 1 |
Definition | ubiquitin-conjugating enzyme E2Q-like protein 1 |
Position | 5p15.31 |
Gene Type | protein-coding |
Mutation summary: | Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72 |
Mutation summary in protein domains | Top |
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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers | Top |
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Loss of Function mutations compare to missense mutations | Top |
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| The ratio of the loss-of-function mutations over missense mutations is 0.00. |
The copy number variations for various cancers | Top |
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The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
COSMIC somatic mutation [Top] | |||
|
Mutation (CDS; AA; Chr) |
Site |
Histology |
Mutation Type |
|---|---|---|---|
c.385A>G; p.K129E; 5:6491248-6491248 |
ovary | other; neoplasm | Substitution - Missense |
c.278C>T; p.T93M; 5:6449171-6449171 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.278C>T; p.T93M; 5:6449171-6449171 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.440C>T; p.T147M; 5:6491303-6491303 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.440C>T; p.T147M; 5:6491303-6491303 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.433G>A; p.V145M; 5:6491296-6491296 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.285C>T; p.R95R; 5:6449178-6449178 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.147C>A; p.T49T; 5:6449040-6449040 |
kidney | other; neoplasm | Substitution - coding silent |
c.281C>A; p.P94Q; 5:6449174-6449174 |
central_nervous_system; brain | glioma; astrocytoma_Grade_II | Substitution - Missense |
c.40T>A; p.F14I; 5:6448933-6448933 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.368G>A; p.R123K; 5:6491231-6491231 |
breast | carcinoma | Substitution - Missense |
c.225C>A; p.R75R; 5:6449118-6449118 |
kidney | other; neoplasm | Substitution - coding silent |
c.252C>A; p.G84G; 5:6449145-6449145 |
kidney | other; neoplasm | Substitution - coding silent |
c.362T>C; p.I121T; 5:6491225-6491225 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.253G>A; p.G85S; 5:6449146-6449146 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.458G>A; p.W153*; 5:6491321-6491321 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Nonsense |
c.418A>G; p.T140A; 5:6491281-6491281 |
pancreas | carcinoma | Substitution - Missense |
c.418A>G; p.T140A; 5:6491281-6491281 |
pancreas | carcinoma; ductal_carcinoma | Substitution - Missense |
c.418A>G; p.T140A; 5:6491281-6491281 |
pancreas | carcinoma | Substitution - Missense |
c.400C>T; p.R134C; 5:6491263-6491263 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.400C>T; p.R134C; 5:6491263-6491263 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.400C>T; p.R134C; 5:6491263-6491263 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.180C>T; p.D60D; 5:6449073-6449073 |
kidney | other; neoplasm | Substitution - coding silent |
c.42C>T; p.F14F; 5:6448935-6448935 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.42C>T; p.F14F; 5:6448935-6448935 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.480C>T; p.D160D; 5:6491343-6491343 |
breast | carcinoma | Substitution - coding silent |
c.484T>C; p.*162R; 5:6491347-6491347 |
liver | carcinoma; hepatocellular_carcinoma | Nonstop extension |
c.400C>A; p.R134S; 5:6491263-6491263 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.484T>C; p.*162R; 5:6491347-6491347 |
liver | carcinoma | Nonstop extension |
c.75C>T; p.F25F; 5:6448968-6448968 |
breast | carcinoma | Substitution - coding silent |
c.22G>A; p.A8T; 5:6448915-6448915 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |