Entrez Gene

Basic Information
Gene ID	1630
Name	DCC
Synonymous	DCC netrin 1 receptor;DCC;DCC netrin 1 receptor
Definition	colorectal cancer suppressor\|colorectal tumor suppressor\|deleted in colorectal cancer protein\|deleted in colorectal carcinoma\|immunoglobulin superfamily DCC subclass member 1\|immunoglobulin superfamily, DCC subclass, member 1\|netrin receptor DCC\|tumor sup
Position	18q21.3
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.13.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.2515G>A; p.D839N; 18:53391714-53391714	skin	malignant_melanoma	Substitution - Missense
c.2068A>G; p.S690G; 18:53322061-53322061	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2515G>A; p.D839N; 18:53391714-53391714	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.3893_3898delGTCAGT; p.S1298_S1300>T; 18:53486953-53486958	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Complex - deletion inframe
c.1055G>A; p.C352Y; 18:53063374-53063374	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3893_3898delGTCAGT; p.S1298_S1300>T; 18:53486953-53486958	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Complex - deletion inframe
c.1231A>G; p.T411A; 18:53066136-53066136	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1707C>T; p.S569S; 18:53205349-53205349	skin	malignant_melanoma	Substitution - coding silent
c.614G>A; p.G205E; 18:52906245-52906245	skin	malignant_melanoma	Substitution - Missense
c.614G>A; p.G205E; 18:52906245-52906245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3798G>A; p.P1266P; 18:53486858-53486858	prostate	carcinoma	Substitution - coding silent
c.1707C>T; p.S569S; 18:53205349-53205349	skin	malignant_melanoma	Substitution - coding silent
c.3798G>A; p.P1266P; 18:53486858-53486858	prostate	adenoma	Substitution - coding silent
c.614G>A; p.G205E; 18:52906245-52906245	skin	malignant_melanoma	Substitution - Missense
c.614G>A; p.G205E; 18:52906245-52906245	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1578A>G; p.Q526Q; 18:53205220-53205220	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2989A>T; p.M997L; 18:53410505-53410505	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.439G>T; p.E147*; 18:52906070-52906070	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2768C>A; p.T923K; 18:53397387-53397387	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3638C>A; p.A1213E; 18:53467912-53467912	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1017C>A; p.N339K; 18:53063336-53063336	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.292C>T; p.L98L; 18:52752254-52752254	skin	malignant_melanoma	Substitution - coding silent
c.4337C>T; p.A1446V; 18:53530646-53530646	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3357G>C; p.V1119V; 18:53450627-53450627	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.3299T>C; p.V1100A; 18:53450569-53450569	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1079C>A; p.P360H; 18:53063398-53063398	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.846C>G; p.L282L; 18:52923855-52923855	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2890A>T; p.I964F; 18:53402848-53402848	liver	carcinoma	Substitution - Missense
c.1981C>T; p.R661*; 18:53305647-53305647	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1981C>T; p.R661*; 18:53305647-53305647	skin	malignant_melanoma	Substitution - Nonsense
c.3817C>A; p.P1273T; 18:53486877-53486877	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1981C>T; p.R661*; 18:53305647-53305647	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1981C>T; p.R661*; 18:53305647-53305647	skin	malignant_melanoma	Substitution - Nonsense
c.1790G>A; p.R597Q; 18:53207746-53207746	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1981C>T; p.R661*; 18:53305647-53305647	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2280C>T; p.I760I; 18:53339828-53339828	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1665C>T; p.N555N; 18:53205307-53205307	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.673G>T; p.E225*; 18:52906304-52906304	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2757G>A; p.S919S; 18:53397376-53397376	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1981C>T; p.R661*; 18:53305647-53305647	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.1981C>T; p.R661*; 18:53305647-53305647	breast	carcinoma	Substitution - Nonsense
c.1981C>T; p.R661*; 18:53305647-53305647	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3817C>A; p.P1273T; 18:53486877-53486877	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3699G>T; p.K1233N; 18:53467973-53467973	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1981C>T; p.R661*; 18:53305647-53305647	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1981C>T; p.R661*; 18:53305647-53305647	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1261+2T>A; p.?; 18:53066168-53066168	lung	carcinoma; adenocarcinoma	Unknown
c.3504A>T; p.P1168P; 18:53459343-53459343	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.434A>T; p.Q145L; 18:52906065-52906065	liver	carcinoma	Substitution - Missense
c.753C>A; p.A251A; 18:52923762-52923762	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.467C>G; p.T156R; 18:52906098-52906098	liver	carcinoma	Substitution - Missense
c.434A>T; p.Q145L; 18:52906065-52906065	liver	carcinoma	Substitution - Missense
c.1465G>T; p.V489L; 18:53179008-53179008	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4043C>T; p.P1348L; 18:53499442-53499442	skin	malignant_melanoma	Substitution - Missense
c.1349G>T; p.R450L; 18:53157443-53157443	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.467C>G; p.T156R; 18:52906098-52906098	liver	carcinoma	Substitution - Missense
c.1512T>G; p.A504A; 18:53179055-53179055	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.359C>T; p.S120F; 18:52752321-52752321	skin	malignant_melanoma	Substitution - Missense
c.1462A>C; p.T488P; 18:53179005-53179005	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1045G>A; p.E349K; 18:53063364-53063364	skin	malignant_melanoma	Substitution - Missense
c.2645C>T; p.T882I; 18:53391844-53391844	skin	malignant_melanoma	Substitution - Missense
c.2239C>A; p.P747T; 18:53339787-53339787	skin	malignant_melanoma	Substitution - Missense
c.2923G>A; p.G975R; 18:53402881-53402881	skin; neck	malignant_melanoma	Substitution - Missense
c.4009C>T; p.R1337*; 18:53499408-53499408	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1349G>A; p.R450H; 18:53157443-53157443	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.4205C>A; p.A1402D; 18:53526710-53526710	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1195C>T; p.Q399*; 18:53066100-53066100	skin	malignant_melanoma	Substitution - Nonsense
c.1349G>A; p.R450H; 18:53157443-53157443	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4009C>T; p.R1337*; 18:53499408-53499408	skin	malignant_melanoma	Substitution - Nonsense
c.1723-2A>G; p.?; 18:53207677-53207677	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.4009C>T; p.R1337*; 18:53499408-53499408	skin	malignant_melanoma	Substitution - Nonsense
c.4009C>T; p.R1337*; 18:53499408-53499408	skin	malignant_melanoma	Substitution - Nonsense
c.4009C>T; p.R1337*; 18:53499408-53499408	skin	malignant_melanoma	Substitution - Nonsense
c.4009C>T; p.R1337*; 18:53499408-53499408	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3605G>T; p.S1202I; 18:53459444-53459444	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4009C>T; p.R1337*; 18:53499408-53499408	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.989C>T; p.P330L; 18:53063308-53063308	breast	carcinoma	Substitution - Missense
c.2217C>A; p.N739K; 18:53339765-53339765	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.673G>A; p.E225K; 18:52906304-52906304	skin	malignant_melanoma	Substitution - Missense
c.1145G>A; p.G382E; 18:53066050-53066050	skin	malignant_melanoma	Substitution - Missense
c.3398G>C; p.R1133P; 18:53459237-53459237	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.728T>A; p.L243Q; 18:52923737-52923737	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2345C>T; p.S782F; 18:53339893-53339893	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.195C>T; p.S65S; 18:52752157-52752157	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2422C>T; p.L808F; 18:53386105-53386105	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.195C>T; p.S65S; 18:52752157-52752157	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1961T>G; p.F654C; 18:53305627-53305627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.97C>T; p.Q33*; 18:52752059-52752059	skin; acral	malignant_melanoma	Substitution - Nonsense
c.4042C>T; p.P1348S; 18:53499441-53499441	skin	malignant_melanoma	Substitution - Missense
c.97C>T; p.Q33*; 18:52752059-52752059	skin; trunk	malignant_melanoma	Substitution - Nonsense
c.4053T>C; p.P1351P; 18:53499452-53499452	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1644G>A; p.W548*; 18:53205286-53205286	skin; mucosal	malignant_melanoma	Substitution - Nonsense
c.3309G>T; p.V1103V; 18:53450579-53450579	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.700C>A; p.P234T; 18:52923709-52923709	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1706C>T; p.S569F; 18:53205348-53205348	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.996G>T; p.W332C; 18:53063315-53063315	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4015A>G; p.T1339A; 18:53499414-53499414	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3619+10T>A; p.?; 18:53459468-53459468	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.3174A>T; p.G1058G; 18:53435154-53435154	liver	carcinoma	Substitution - coding silent
c.4037C>T; p.A1346V; 18:53499436-53499436	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.73G>A; p.A25T; 18:52340860-52340860	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2794A>T; p.S932C; 18:53397413-53397413	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1767A>C; p.K589N; 18:53207723-53207723	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3427G>T; p.G1143C; 18:53459266-53459266	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1365G>A; p.A455A; 18:53157459-53157459	skin	malignant_melanoma	Substitution - coding silent
c.1365G>A; p.A455A; 18:53157459-53157459	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1365G>A; p.A455A; 18:53157459-53157459	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3693G>A; p.R1231R; 18:53467967-53467967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3839G>A; p.R1280Q; 18:53486899-53486899	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2625G>A; p.T875T; 18:53391824-53391824	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.152C>T; p.T51I; 18:52752114-52752114	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2943C>A; p.I981I; 18:53410459-53410459	liver	carcinoma	Substitution - coding silent
c.1365G>A; p.A455A; 18:53157459-53157459	skin	malignant_melanoma	Substitution - coding silent
c.1113C>A; p.V371V; 18:53063432-53063432	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.177C>T; p.L59L; 18:52752139-52752139	skin	malignant_melanoma	Substitution - coding silent
c.3117C>G; p.F1039L; 18:53410633-53410633	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3262G>T; p.G1088C; 18:53450532-53450532	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1651C>T; p.P551S; 18:53205293-53205293	oesophagus	carcinoma	Substitution - Missense
c.1832A>G; p.D611G; 18:53207788-53207788	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2934T>C; p.T978T; 18:53402892-53402892	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1596A>T; p.E532D; 18:53205238-53205238	skin	malignant_melanoma	Substitution - Missense
c.2202G>A; p.V734V; 18:53339750-53339750	skin	malignant_melanoma	Substitution - coding silent
c.599G>A; p.S200N; 18:52906230-52906230	liver	carcinoma	Substitution - Missense
c.3404C>T; p.T1135I; 18:53459243-53459243	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.993A>C; p.P331P; 18:53063312-53063312	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3404C>T; p.T1135I; 18:53459243-53459243	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3133G>A; p.E1045K; 18:53416126-53416126	skin	malignant_melanoma	Substitution - Missense
c.3744G>A; p.V1248V; 18:53486804-53486804	liver	carcinoma	Substitution - coding silent
c.2130G>T; p.W710C; 18:53322123-53322123	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3756G>A; p.P1252P; 18:53486816-53486816	oesophagus	carcinoma	Substitution - coding silent
c.993A>C; p.P331P; 18:53063312-53063312	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.2365A>C; p.S789R; 18:53386048-53386048	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.195C>A; p.S65S; 18:52752157-52752157	soft_tissue; blood_vessel	angiosarcoma	Substitution - coding silent
c.599G>A; p.S200N; 18:52906230-52906230	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1138G>T; p.V380L; 18:53063457-53063457	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3995C>A; p.P1332H; 18:53499394-53499394	pancreas	carcinoma	Substitution - Missense
c.1582C>A; p.P528T; 18:53205224-53205224	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2164+1G>A; p.?; 18:53322158-53322158	liver	carcinoma	Unknown
c.13C>G; p.L5V; 18:52340800-52340800	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.74C>T; p.A25V; 18:52340861-52340861	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.74C>T; p.A25V; 18:52340861-52340861	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2937delT; p.Y980fs*63; 18:53410453-53410453	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2209C>A; p.Q737K; 18:53339757-53339757	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3475G>A; p.E1159K; 18:53459314-53459314	skin	malignant_melanoma	Substitution - Missense
c.3835C>T; p.L1279F; 18:53486895-53486895	skin	malignant_melanoma	Substitution - Missense
c.2647G>A; p.V883I; 18:53391846-53391846	breast	carcinoma	Substitution - Missense
c.463G>A; p.D155N; 18:52906094-52906094	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.209C>T; p.P70L; 18:52752171-52752171	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3608C>A; p.T1203N; 18:53459447-53459447	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.399A>C; p.K133N; 18:52752361-52752361	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.4326C>T; p.I1442I; 18:53530635-53530635	skin; hand	malignant_melanoma	Substitution - coding silent
c.1912-9A>G; p.?; 18:53305569-53305569	liver	carcinoma	Unknown
c.4308G>A; p.M1436I; 18:53530617-53530617	skin	malignant_melanoma	Substitution - Missense
c.1912-9A>G; p.?; 18:53305569-53305569	liver	carcinoma	Unknown
c.3257C>T; p.P1086L; 18:53450527-53450527	breast	carcinoma	Substitution - Missense
c.2181T>A; p.D727E; 18:53339729-53339729	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2754C>A; p.F918L; 18:53397373-53397373	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.981C>T; p.V327V; 18:52925366-52925366	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2139A>T; p.A713A; 18:53322132-53322132	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3292C>A; p.L1098M; 18:53450562-53450562	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3108T>C; p.P1036P; 18:53410624-53410624	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.4123C>T; p.P1375S; 18:53526628-53526628	skin	malignant_melanoma	Substitution - Missense
c.1523G>T; p.W508L; 18:53179066-53179066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2910C>A; p.P970P; 18:53402868-53402868	liver	carcinoma	Substitution - coding silent
c.3108T>C; p.P1036P; 18:53410624-53410624	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1479G>T; p.K493N; 18:53179022-53179022	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1296C>A; p.P432P; 18:53157390-53157390	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3910G>A; p.G1304R; 18:53499309-53499309	skin	malignant_melanoma	Substitution - Missense
c.2664C>T; p.S888S; 18:53391863-53391863	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.3126G>A; p.L1042L; 18:53410642-53410642	skin	malignant_melanoma	Substitution - coding silent
c.985G>T; p.V329F; 18:52925370-52925370	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.985G>T; p.V329F; 18:52925370-52925370	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.608A>G; p.Q203R; 18:52906239-52906239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4018C>G; p.H1340D; 18:53499417-53499417	skin; neck	malignant_melanoma	Substitution - Missense
c.2316G>A; p.V772V; 18:53339864-53339864	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3974A>T; p.E1325V; 18:53499373-53499373	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3624A>G; p.Q1208Q; 18:53467898-53467898	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3211G>A; p.D1071N; 18:53435191-53435191	skin	malignant_melanoma	Substitution - Missense
c.643C>T; p.R215*; 18:52906274-52906274	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4149C>T; p.S1383S; 18:53526654-53526654	skin	malignant_melanoma	Substitution - coding silent
c.3194delT; p.D1066fs*4; 18:53435174-53435174	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.3211G>A; p.D1071N; 18:53435191-53435191	skin	malignant_melanoma	Substitution - Missense
c.1219G>A; p.G407R; 18:53066124-53066124	skin; arm	malignant_melanoma	Substitution - Missense
c.3529G>A; p.D1177N; 18:53459368-53459368	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.562C>T; p.R188*; 18:52906193-52906193	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.562C>T; p.R188*; 18:52906193-52906193	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3389G>C; p.R1130T; 18:53450659-53450659	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2290G>A; p.V764I; 18:53339838-53339838	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2308G>A; p.E770K; 18:53339856-53339856	skin	malignant_melanoma	Substitution - Missense
c.1483G>T; p.E495*; 18:53179026-53179026	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Nonsense
c.4107G>A; p.Q1369Q; 18:53499506-53499506	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1536G>T; p.E512D; 18:53179079-53179079	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3402C>T; p.A1134A; 18:53459241-53459241	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2708T>C; p.L903P; 18:53397327-53397327	bone	osteosarcoma	Substitution - Missense
c.178G>T; p.D60Y; 18:52752140-52752140	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1337G>A; p.R446H; 18:53157431-53157431	pancreas	carcinoma	Substitution - Missense
c.1337G>A; p.R446H; 18:53157431-53157431	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1337G>A; p.R446H; 18:53157431-53157431	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2887G>A; p.V963I; 18:53402845-53402845	breast	carcinoma	Substitution - Missense
c.1881G>T; p.Q627H; 18:53215567-53215567	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2839G>T; p.A947S; 18:53402797-53402797	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1337G>A; p.R446H; 18:53157431-53157431	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.420G>A; p.L140L; 18:52906051-52906051	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2607C>T; p.V869V; 18:53391806-53391806	skin	malignant_melanoma	Substitution - coding silent
c.2139A>G; p.A713A; 18:53322132-53322132	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1337G>A; p.R446H; 18:53157431-53157431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2887G>A; p.V963I; 18:53402845-53402845	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1337G>A; p.R446H; 18:53157431-53157431	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2887G>A; p.V963I; 18:53402845-53402845	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2261T>C; p.V754A; 18:53339809-53339809	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3604A>T; p.S1202C; 18:53459443-53459443	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2655G>A; p.W885*; 18:53391854-53391854	skin	malignant_melanoma	Substitution - Nonsense
c.549C>T; p.I183I; 18:52906180-52906180	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1633C>A; p.L545I; 18:53205275-53205275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1041T>A; p.D347E; 18:53063360-53063360	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1238C>A; p.A413E; 18:53066143-53066143	liver	carcinoma	Substitution - Missense
c.3592C>A; p.L1198M; 18:53459431-53459431	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1238C>A; p.A413E; 18:53066143-53066143	liver	carcinoma	Substitution - Missense
c.2881C>T; p.R961C; 18:53402839-53402839	skin	malignant_melanoma	Substitution - Missense
c.1207G>A; p.E403K; 18:53066112-53066112	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4020C>A; p.H1340Q; 18:53499419-53499419	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1207G>A; p.E403K; 18:53066112-53066112	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1207G>A; p.E403K; 18:53066112-53066112	skin	malignant_melanoma	Substitution - Missense
c.1207G>A; p.E403K; 18:53066112-53066112	skin	malignant_melanoma	Substitution - Missense
c.1012T>C; p.S338P; 18:53063331-53063331	liver	carcinoma	Substitution - Missense
c.2437A>C; p.T813P; 18:53386120-53386120	oesophagus	carcinoma	Substitution - Missense
c.2762T>C; p.M921T; 18:53397381-53397381	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3348C>T; p.I1116I; 18:53450618-53450618	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3348C>T; p.I1116I; 18:53450618-53450618	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2520C>G; p.L840L; 18:53391719-53391719	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3780G>A; p.Q1260Q; 18:53486840-53486840	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.147C>T; p.A49A; 18:52752109-52752109	skin	malignant_melanoma	Substitution - coding silent
c.4162G>A; p.G1388R; 18:53526667-53526667	skin	malignant_melanoma	Substitution - Missense
c.1936C>A; p.P646T; 18:53305602-53305602	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1351C>T; p.P451S; 18:53157445-53157445	skin	malignant_melanoma	Substitution - Missense
c.3705G>A; p.M1235I; 18:53467979-53467979	skin	malignant_melanoma	Substitution - Missense
c.737C>T; p.P246L; 18:52923746-52923746	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.4241A>T; p.E1414V; 18:53526746-53526746	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4186C>T; p.P1396S; 18:53526691-53526691	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2098A>G; p.T700A; 18:53322091-53322091	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1477A>T; p.K493*; 18:53179020-53179020	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4186C>T; p.P1396S; 18:53526691-53526691	skin	malignant_melanoma	Substitution - Missense
c.766G>T; p.D256Y; 18:52923775-52923775	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3605G>A; p.S1202N; 18:53459444-53459444	skin	malignant_melanoma	Substitution - Missense
c.3825G>A; p.P1275P; 18:53486885-53486885	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1963A>T; p.I655F; 18:53305629-53305629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3073C>G; p.R1025G; 18:53410589-53410589	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3605G>A; p.S1202N; 18:53459444-53459444	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3166C>A; p.R1056S; 18:53435146-53435146	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1817C>T; p.P606L; 18:53207773-53207773	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.3825G>A; p.P1275P; 18:53486885-53486885	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3620-6T>C; p.?; 18:53467888-53467888	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.338G>T; p.G113V; 18:52752300-52752300	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.263G>A; p.R88K; 18:52752225-52752225	skin	malignant_melanoma	Substitution - Missense
c.263G>A; p.R88K; 18:52752225-52752225	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1425A>G; p.R475R; 18:53178968-53178968	skin	malignant_melanoma	Substitution - coding silent
c.345C>T; p.Y115Y; 18:52752307-52752307	skin	malignant_melanoma	Substitution - coding silent
c.217A>C; p.K73Q; 18:52752179-52752179	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3307G>T; p.V1103L; 18:53450577-53450577	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.879C>A; p.S293R; 18:52925264-52925264	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myeloid_leukaemia	Substitution - Missense
c.2514A>C; p.P838P; 18:53391713-53391713	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - coding silent
c.1750A>G; p.K584E; 18:53207706-53207706	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1321T>C; p.S441P; 18:53157415-53157415	breast	carcinoma	Substitution - Missense
c.3649A>G; p.M1217V; 18:53467923-53467923	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1519G>A; p.E507K; 18:53179062-53179062	skin	malignant_melanoma	Substitution - Missense
c.3812G>A; p.G1271E; 18:53486872-53486872	skin; extremity	malignant_melanoma	Substitution - Missense
c.256G>A; p.D86N; 18:52752218-52752218	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1028A>T; p.Y343F; 18:53063347-53063347	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.256G>A; p.D86N; 18:52752218-52752218	skin	malignant_melanoma	Substitution - Missense
c.2000G>A; p.R667H; 18:53305666-53305666	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1523G>A; p.W508*; 18:53179066-53179066	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2000G>A; p.R667H; 18:53305666-53305666	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.213G>A; p.V71V; 18:52752175-52752175	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.959G>C; p.S320T; 18:52925344-52925344	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4210G>A; p.E1404K; 18:53526715-53526715	breast	carcinoma	Substitution - Missense
c.28G>A; p.V10I; 18:52340815-52340815	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.287C>G; p.S96C; 18:52752249-52752249	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1940C>T; p.P647L; 18:53305606-53305606	skin; acral	malignant_melanoma	Substitution - Missense
c.287C>G; p.S96C; 18:52752249-52752249	breast	carcinoma	Substitution - Missense
c.2124C>T; p.S708S; 18:53322117-53322117	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2726G>A; p.G909D; 18:53397345-53397345	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.762delA; p.D256fs*45; 18:52923771-52923771	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4048C>A; p.L1350I; 18:53499447-53499447	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.829G>A; p.E277K; 18:52923838-52923838	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.829G>A; p.E277K; 18:52923838-52923838	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3897G>T; p.Q1299H; 18:53486957-53486957	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.75G>A; p.A25A; 18:52340862-52340862	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1058C>A; p.T353K; 18:53063377-53063377	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3789A>T; p.G1263G; 18:53486849-53486849	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.196G>A; p.D66N; 18:52752158-52752158	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1488C>T; p.A496A; 18:53179031-53179031	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1572G>C; p.E524D; 18:53179115-53179115	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2925G>A; p.G975G; 18:53402883-53402883	skin	malignant_melanoma	Substitution - coding silent
c.2323G>A; p.D775N; 18:53339871-53339871	skin	malignant_melanoma	Substitution - Missense
c.1789C>T; p.R597*; 18:53207745-53207745	skin	malignant_melanoma	Substitution - Nonsense
c.3747C>T; p.S1249S; 18:53486807-53486807	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1789C>T; p.R597*; 18:53207745-53207745	skin	malignant_melanoma	Substitution - Nonsense
c.194C>A; p.S65Y; 18:52752156-52752156	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.3668C>T; p.S1223L; 18:53467942-53467942	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2323G>A; p.D775N; 18:53339871-53339871	skin	malignant_melanoma	Substitution - Missense
c.1324A>T; p.S442C; 18:53157418-53157418	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1173G>A; p.V391V; 18:53066078-53066078	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.1756G>A; p.E586K; 18:53207712-53207712	skin	malignant_melanoma	Substitution - Missense
c.1216G>A; p.A406T; 18:53066121-53066121	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1173G>A; p.V391V; 18:53066078-53066078	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.4054C>T; p.P1352S; 18:53499453-53499453	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2068A>C; p.S690R; 18:53322061-53322061	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3417C>T; p.G1139G; 18:53459256-53459256	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.974T>C; p.L325P; 18:52925359-52925359	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3442C>A; p.L1148I; 18:53459281-53459281	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3736G>T; p.A1246S; 18:53468010-53468010	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1890C>T; p.S630S; 18:53215576-53215576	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3027C>T; p.I1009I; 18:53410543-53410543	skin	malignant_melanoma	Substitution - coding silent
c.3027C>T; p.I1009I; 18:53410543-53410543	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3073C>T; p.R1025*; 18:53410589-53410589	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.3688C>A; p.P1230T; 18:53467962-53467962	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2818T>C; p.Y940H; 18:53397437-53397437	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1784G>A; p.S595N; 18:53207740-53207740	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3472G>A; p.E1158K; 18:53459311-53459311	skin; scalp	malignant_melanoma	Substitution - Missense
c.3073C>T; p.R1025*; 18:53410589-53410589	skin; sole	malignant_melanoma; acral_lentiginous	Substitution - Nonsense
c.1479G>A; p.K493K; 18:53179022-53179022	skin	malignant_melanoma	Substitution - coding silent
c.3073C>T; p.R1025*; 18:53410589-53410589	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1865C>A; p.P622Q; 18:53215551-53215551	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3816T>A; p.Y1272*; 18:53486876-53486876	liver	carcinoma	Substitution - Nonsense
c.136C>T; p.P46S; 18:52752098-52752098	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.136C>T; p.P46S; 18:52752098-52752098	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.136C>T; p.P46S; 18:52752098-52752098	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.2690C>A; p.S897*; 18:53397309-53397309	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1788T>C; p.L596L; 18:53207744-53207744	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1030G>A; p.E344K; 18:53063349-53063349	skin	malignant_melanoma	Substitution - Missense
c.1102G>A; p.G368R; 18:53063421-53063421	skin	malignant_melanoma	Substitution - Missense
c.2684A>G; p.Y895C; 18:53391883-53391883	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2684A>G; p.Y895C; 18:53391883-53391883	large_intestine; colon	carcinoma	Substitution - Missense
c.1571A>G; p.E524G; 18:53179114-53179114	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2596G>A; p.D866N; 18:53391795-53391795	skin	malignant_melanoma	Substitution - Missense
c.3130+6A>C; p.?; 18:53410652-53410652	pancreas	carcinoma; adenocarcinoma	Unknown
c.3499A>G; p.K1167E; 18:53459338-53459338	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3229G>T; p.E1077*; 18:53435209-53435209	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3879C>T; p.F1293F; 18:53486939-53486939	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3879C>T; p.F1293F; 18:53486939-53486939	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3797C>T; p.P1266L; 18:53486857-53486857	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3879C>T; p.F1293F; 18:53486939-53486939	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3986G>A; p.R1329K; 18:53499385-53499385	skin	malignant_melanoma	Substitution - Missense
c.4257G>A; p.V1419V; 18:53530566-53530566	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3857C>A; p.T1286K; 18:53486917-53486917	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3986G>A; p.R1329K; 18:53499385-53499385	skin	malignant_melanoma	Substitution - Missense
c.2423T>A; p.L808H; 18:53386106-53386106	skin	malignant_melanoma	Substitution - Missense
c.3880G>A; p.G1294R; 18:53486940-53486940	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1295C>T; p.P432L; 18:53157389-53157389	skin	malignant_melanoma	Substitution - Missense
c.3620G>T; p.G1207V; 18:53467894-53467894	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4144G>A; p.A1382T; 18:53526649-53526649	skin	malignant_melanoma	Substitution - Missense
c.3124C>A; p.L1042M; 18:53410640-53410640	pancreas	carcinoma; adenocarcinoma	Substitution - Missense
c.3291C>A; p.N1097K; 18:53450561-53450561	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.893C>T; p.S298F; 18:52925278-52925278	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.449C>T; p.T150I; 18:52906080-52906080	pancreas	carcinoma	Substitution - Missense
c.988C>T; p.P330S; 18:53063307-53063307	skin	malignant_melanoma	Substitution - Missense
c.4301G>A; p.G1434E; 18:53530610-53530610	skin	malignant_melanoma	Substitution - Missense
c.2624C>T; p.T875M; 18:53391823-53391823	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2510T>C; p.V837A; 18:53391709-53391709	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.15T>G; p.L5L; 18:52340802-52340802	liver	carcinoma	Substitution - coding silent
c.3881G>A; p.G1294E; 18:53486941-53486941	skin	malignant_melanoma	Substitution - Missense
c.3074G>A; p.R1025Q; 18:53410590-53410590	skin	malignant_melanoma	Substitution - Missense
c.3742G>A; p.V1248M; 18:53486802-53486802	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1045G>C; p.E349Q; 18:53063364-53063364	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3996C>T; p.P1332P; 18:53499395-53499395	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.3194T>G; p.V1065G; 18:53435174-53435174	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1732G>T; p.V578F; 18:53207688-53207688	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1566G>A; p.Q522Q; 18:53179109-53179109	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.238C>A; p.H80N; 18:52752200-52752200	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.255G>A; p.M85I; 18:52752217-52752217	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2635C>T; p.R879*; 18:53391834-53391834	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.3969C>A; p.S1323R; 18:53499368-53499368	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4072G>A; p.E1358K; 18:53499471-53499471	skin	malignant_melanoma	Substitution - Missense
c.1850C>G; p.T617R; 18:53207806-53207806	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1252C>A; p.P418T; 18:53066157-53066157	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1707C>A; p.S569S; 18:53205349-53205349	prostate	adenoma	Substitution - coding silent
c.904G>A; p.D302N; 18:52925289-52925289	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3824C>A; p.P1275Q; 18:53486884-53486884	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2843C>A; p.P948H; 18:53402801-53402801	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1382C>T; p.T461I; 18:53157476-53157476	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3824C>A; p.P1275Q; 18:53486884-53486884	urinary_tract; bladder	carcinoma	Substitution - Missense
c.397A>C; p.K133Q; 18:52752359-52752359	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2869G>A; p.E957K; 18:53402827-53402827	skin	malignant_melanoma	Substitution - Missense
c.3824C>A; p.P1275Q; 18:53486884-53486884	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3824C>A; p.P1275Q; 18:53486884-53486884	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.631C>T; p.R211*; 18:52906262-52906262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3398G>A; p.R1133Q; 18:53459237-53459237	skin	malignant_melanoma	Substitution - Missense
c.336G>A; p.E112E; 18:52752298-52752298	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3113T>C; p.L1038P; 18:53410629-53410629	liver	carcinoma	Substitution - Missense
c.3028A>G; p.M1010V; 18:53410544-53410544	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1776C>T; p.T592T; 18:53207732-53207732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3131-4G>T; p.?; 18:53416120-53416120	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.3113T>C; p.L1038P; 18:53410629-53410629	liver	carcinoma	Substitution - Missense
c.4207C>T; p.P1403S; 18:53526712-53526712	skin	malignant_melanoma	Substitution - Missense
c.2306C>T; p.A769V; 18:53339854-53339854	skin; acral	malignant_melanoma	Substitution - Missense
c.3061C>T; p.R1021*; 18:53410577-53410577	skin	malignant_melanoma	Substitution - Nonsense
c.2360A>G; p.E787G; 18:53386043-53386043	liver	carcinoma	Substitution - Missense
c.3061C>T; p.R1021*; 18:53410577-53410577	skin	malignant_melanoma	Substitution - Nonsense
c.3061C>T; p.R1021*; 18:53410577-53410577	skin	malignant_melanoma	Substitution - Nonsense
c.2654G>A; p.W885*; 18:53391853-53391853	skin; mucosal	malignant_melanoma	Substitution - Nonsense
c.727C>T; p.L243L; 18:52923736-52923736	skin	malignant_melanoma	Substitution - coding silent
c.1157G>A; p.R386Q; 18:53066062-53066062	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1229A>G; p.Q410R; 18:53066134-53066134	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.R386Q; 18:53066062-53066062	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3907G>A; p.E1303K; 18:53499306-53499306	oesophagus	carcinoma	Substitution - Missense
c.1157G>A; p.R386Q; 18:53066062-53066062	skin	malignant_melanoma	Substitution - Missense
c.3393G>A; p.K1131K; 18:53459232-53459232	skin	malignant_melanoma	Substitution - coding silent
c.3536C>A; p.P1179H; 18:53459375-53459375	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3641G>A; p.G1214E; 18:53467915-53467915	skin	malignant_melanoma	Substitution - Missense
c.3534T>A; p.S1178S; 18:53459373-53459373	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2176C>T; p.P726S; 18:53339724-53339724	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1816C>T; p.P606S; 18:53207772-53207772	skin	malignant_melanoma	Substitution - Missense
c.550C>T; p.P184S; 18:52906181-52906181	skin	malignant_melanoma	Substitution - Missense
c.208C>T; p.P70S; 18:52752170-52752170	skin	malignant_melanoma	Substitution - Missense
c.2889C>T; p.V963V; 18:53402847-53402847	skin	malignant_melanoma	Substitution - coding silent
c.2340T>A; p.Y780*; 18:53339888-53339888	skin	malignant_melanoma	Substitution - Nonsense
c.3116T>C; p.F1039S; 18:53410632-53410632	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3116T>C; p.F1039S; 18:53410632-53410632	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2176C>T; p.P726S; 18:53339724-53339724	skin	malignant_melanoma	Substitution - Missense
c.3482A>G; p.E1161G; 18:53459321-53459321	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3393G>A; p.K1131K; 18:53459232-53459232	skin	malignant_melanoma	Substitution - coding silent
c.243G>A; p.L81L; 18:52752205-52752205	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1487C>A; p.A496D; 18:53179030-53179030	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1763T>C; p.L588P; 18:53207719-53207719	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.917G>C; p.G306A; 18:52925302-52925302	liver	carcinoma	Substitution - Missense
c.2263G>T; p.V755L; 18:53339811-53339811	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1579G>A; p.V527I; 18:53205221-53205221	skin; trunk	malignant_melanoma	Substitution - Missense
c.1035C>A; p.S345R; 18:53063354-53063354	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.917G>C; p.G306A; 18:52925302-52925302	liver	carcinoma	Substitution - Missense
c.1501C>T; p.R501*; 18:53179044-53179044	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; non_functioning	Substitution - Nonsense
c.1501C>T; p.R501*; 18:53179044-53179044	skin	malignant_melanoma	Substitution - Nonsense
c.1501C>T; p.R501*; 18:53179044-53179044	skin	malignant_melanoma	Substitution - Nonsense
c.1501C>T; p.R501*; 18:53179044-53179044	skin	malignant_melanoma	Substitution - Nonsense
c.1531G>T; p.G511*; 18:53179074-53179074	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.2746T>C; p.Y916H; 18:53397365-53397365	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3403A>G; p.T1135A; 18:53459242-53459242	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.823C>A; p.R275R; 18:52923832-52923832	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3245A>G; p.Q1082R; 18:53450515-53450515	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.440A>T; p.E147V; 18:52906071-52906071	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.121C>T; p.R41C; 18:52752083-52752083	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3691C>T; p.R1231W; 18:53467965-53467965	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2370C>T; p.S790S; 18:53386053-53386053	skin	malignant_melanoma	Substitution - coding silent
c.3232C>A; p.P1078T; 18:53450502-53450502	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4028G>A; p.R1343H; 18:53499427-53499427	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3232C>A; p.P1078T; 18:53450502-53450502	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.3243A>T; p.G1081G; 18:53450513-53450513	breast	carcinoma	Substitution - coding silent
c.3721C>T; p.Q1241*; 18:53467995-53467995	oesophagus	carcinoma	Substitution - Nonsense
c.1655C>A; p.A552D; 18:53205297-53205297	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3680G>A; p.R1227H; 18:53467954-53467954	skin	malignant_melanoma	Substitution - Missense
c.2482C>T; p.P828S; 18:53391681-53391681	skin	malignant_melanoma	Substitution - Missense
c.1683C>T; p.Y561Y; 18:53205325-53205325	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.747A>G; p.V249V; 18:52923756-52923756	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1879C>T; p.Q627*; 18:53215565-53215565	breast	carcinoma	Substitution - Nonsense
c.3680G>A; p.R1227H; 18:53467954-53467954	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1671A>T; p.P557P; 18:53205313-53205313	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2281G>A; p.G761S; 18:53339829-53339829	prostate	adenoma	Substitution - Missense
c.1590A>G; p.P530P; 18:53205232-53205232	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3366C>A; p.T1122T; 18:53450636-53450636	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.790T>A; p.S264T; 18:52923799-52923799	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1769A>T; p.K590I; 18:53207725-53207725	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2267G>A; p.R756Q; 18:53339815-53339815	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1982G>A; p.R661Q; 18:53305648-53305648	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1982G>A; p.R661Q; 18:53305648-53305648	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4006G>C; p.V1336L; 18:53499405-53499405	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.427C>T; p.L143F; 18:52906058-52906058	skin	malignant_melanoma	Substitution - Missense
c.4247C>T; p.S1416L; 18:53526752-53526752	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1300G>A; p.D434N; 18:53157394-53157394	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1939C>T; p.P647S; 18:53305605-53305605	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3310G>C; p.V1104L; 18:53450580-53450580	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.427C>T; p.L143F; 18:52906058-52906058	skin	malignant_melanoma	Substitution - Missense
c.337G>T; p.G113*; 18:52752299-52752299	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1124A>T; p.D375V; 18:53063443-53063443	skin	malignant_melanoma	Substitution - Missense
c.2336G>A; p.R779Q; 18:53339884-53339884	skin	malignant_melanoma	Substitution - Missense
c.1226C>T; p.A409V; 18:53066131-53066131	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2335C>T; p.R779*; 18:53339883-53339883	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1124A>T; p.D375V; 18:53063443-53063443	skin	malignant_melanoma	Substitution - Missense
c.2368T>C; p.S790P; 18:53386051-53386051	skin	malignant_melanoma	Substitution - Missense
c.2336G>A; p.R779Q; 18:53339884-53339884	skin	malignant_melanoma	Substitution - Missense
c.2712T>C; p.S904S; 18:53397331-53397331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3872G>A; p.R1291Q; 18:53486932-53486932	skin	malignant_melanoma	Substitution - Missense
c.2554G>A; p.A852T; 18:53391753-53391753	breast	carcinoma	Substitution - Missense
c.2455+2T>A; p.?; 18:53386140-53386140	ovary	carcinoma; serous_carcinoma	Unknown
c.3983G>T; p.S1328I; 18:53499382-53499382	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2266C>T; p.R756*; 18:53339814-53339814	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4052C>T; p.P1351L; 18:53499451-53499451	skin	malignant_melanoma	Substitution - Missense
c.2266C>T; p.R756*; 18:53339814-53339814	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2266C>T; p.R756*; 18:53339814-53339814	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1859A>G; p.D620G; 18:53207815-53207815	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4102T>C; p.S1368P; 18:53499501-53499501	central_nervous_system; brain	glioma	Substitution - Missense
c.2266C>T; p.R756*; 18:53339814-53339814	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1467delG; p.G490fs*3; 18:53179010-53179010	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.387T>A; p.S129R; 18:52752349-52752349	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.3662A>G; p.E1221G; 18:53467936-53467936	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3309G>A; p.V1103V; 18:53450579-53450579	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2299C>A; p.P767T; 18:53339847-53339847	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2816C>T; p.T939M; 18:53397435-53397435	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3315C>T; p.T1105T; 18:53450585-53450585	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.693A>C; p.L231F; 18:52906324-52906324	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1987A>G; p.R663G; 18:53305653-53305653	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3080C>T; p.S1027L; 18:53410596-53410596	skin	malignant_melanoma	Substitution - Missense
c.3252delC; p.P1086fs*15; 18:53450522-53450522	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3252delC; p.P1086fs*15; 18:53450522-53450522	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3315C>T; p.T1105T; 18:53450585-53450585	skin	malignant_melanoma	Substitution - coding silent
c.3252delC; p.P1086fs*15; 18:53450522-53450522	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3303C>T; p.I1101I; 18:53450573-53450573	skin	malignant_melanoma	Substitution - coding silent
c.1821C>T; p.G607G; 18:53207777-53207777	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.284G>C; p.G95A; 18:52752246-52752246	skin	malignant_melanoma	Substitution - Missense
c.1285C>T; p.P429S; 18:53157379-53157379	skin	malignant_melanoma	Substitution - Missense
c.3669G>C; p.S1223S; 18:53467943-53467943	liver	carcinoma	Substitution - coding silent
c.157C>T; p.R53W; 18:52752119-52752119	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1920A>C; p.K640N; 18:53305586-53305586	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1570G>C; p.E524Q; 18:53179113-53179113	liver	carcinoma	Substitution - Missense
c.1634T>G; p.L545R; 18:53205276-53205276	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3174A>G; p.G1058G; 18:53435154-53435154	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.637T>A; p.S213T; 18:52906268-52906268	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.649C>A; p.P217T; 18:52906280-52906280	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4012C>A; p.P1338T; 18:53499411-53499411	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3732T>C; p.N1244N; 18:53468006-53468006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3364A>C; p.T1122P; 18:53450634-53450634	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1018C>A; p.L340M; 18:53063337-53063337	liver	carcinoma	Substitution - Missense
c.1166G>T; p.G389V; 18:53066071-53066071	liver	carcinoma	Substitution - Missense
c.1209A>C; p.E403D; 18:53066114-53066114	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2991G>A; p.M997I; 18:53410507-53410507	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3652T>A; p.S1218T; 18:53467926-53467926	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3192A>T; p.P1064P; 18:53435172-53435172	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1010C>T; p.P337L; 18:53063329-53063329	skin	malignant_melanoma	Substitution - Missense
c.1166G>T; p.G389V; 18:53066071-53066071	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1876C>T; p.P626S; 18:53215562-53215562	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2067A>T; p.G689G; 18:53322060-53322060	liver	carcinoma	Substitution - coding silent
c.1275C>A; p.S425S; 18:53157369-53157369	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2317C>T; p.R773C; 18:53339865-53339865	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2317C>T; p.R773C; 18:53339865-53339865	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3115T>C; p.F1039L; 18:53410631-53410631	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4279G>A; p.E1427K; 18:53530588-53530588	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1169T>G; p.V390G; 18:53066074-53066074	breast	carcinoma	Substitution - Missense
c.2447C>T; p.S816F; 18:53386130-53386130	skin	malignant_melanoma	Substitution - Missense
c.460G>T; p.G154*; 18:52906091-52906091	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.2067A>T; p.G689G; 18:53322060-53322060	liver	carcinoma	Substitution - coding silent
c.1885G>A; p.V629I; 18:53215571-53215571	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1168G>T; p.V390L; 18:53066073-53066073	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2889C>A; p.V963V; 18:53402847-53402847	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2769delA; p.N925fs*9; 18:53397388-53397388	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1818G>C; p.P606P; 18:53207774-53207774	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1884C>T; p.N628N; 18:53215570-53215570	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3166C>T; p.R1056C; 18:53435146-53435146	skin	malignant_melanoma	Substitution - Missense
c.3047C>T; p.T1016I; 18:53410563-53410563	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3184_3185TA>GT; p.Y1062V; 18:53435164-53435165	skin	malignant_melanoma	Substitution - Missense
c.2908C>T; p.P970S; 18:53402866-53402866	skin; scalp	malignant_melanoma	Substitution - Missense
c.2318G>T; p.R773L; 18:53339866-53339866	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1805A>G; p.N602S; 18:53207761-53207761	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1860C>T; p.D620D; 18:53207816-53207816	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1898T>C; p.V633A; 18:53215584-53215584	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2164+5G>T; p.?; 18:53322162-53322162	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1153T>G; p.L385V; 18:53066058-53066058	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1860C>T; p.D620D; 18:53207816-53207816	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1860C>T; p.D620D; 18:53207816-53207816	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.4112-2A>G; p.?; 18:53526615-53526615	stomach	carcinoma; adenocarcinoma	Unknown
c.3958C>G; p.H1320D; 18:53499357-53499357	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3609C>A; p.T1203T; 18:53459448-53459448	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3801T>A; p.S1267S; 18:53486861-53486861	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.198C>A; p.D66E; 18:52752160-52752160	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1613C>T; p.S538F; 18:53205255-53205255	skin	malignant_melanoma	Substitution - Missense
c.3535C>A; p.P1179T; 18:53459374-53459374	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.60T>C; p.A20A; 18:52340847-52340847	thyroid	other; neoplasm	Substitution - coding silent
c.1654G>C; p.A552P; 18:53205296-53205296	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1820G>T; p.G607V; 18:53207776-53207776	liver	carcinoma	Substitution - Missense
c.2151G>T; p.E717D; 18:53322144-53322144	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1820G>T; p.G607V; 18:53207776-53207776	liver	carcinoma	Substitution - Missense
c.2094C>A; p.A698A; 18:53322087-53322087	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1999C>T; p.R667C; 18:53305665-53305665	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1776C>A; p.T592T; 18:53207732-53207732	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.426C>T; p.F142F; 18:52906057-52906057	skin	malignant_melanoma	Substitution - coding silent
c.1328G>A; p.R443Q; 18:53157422-53157422	skin	malignant_melanoma	Substitution - Missense
c.2980G>A; p.D994N; 18:53410496-53410496	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1328G>A; p.R443Q; 18:53157422-53157422	prostate	carcinoma	Substitution - Missense
c.1328G>A; p.R443Q; 18:53157422-53157422	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1328G>A; p.R443Q; 18:53157422-53157422	skin	malignant_melanoma	Substitution - Missense
c.158G>A; p.R53Q; 18:52752120-52752120	skin	malignant_melanoma	Substitution - Missense
c.2956T>C; p.L986L; 18:53410472-53410472	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2413G>A; p.G805R; 18:53386096-53386096	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2197C>T; p.H733Y; 18:53339745-53339745	skin	malignant_melanoma	Substitution - Missense
c.3910G>T; p.G1304*; 18:53499309-53499309	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2909C>T; p.P970L; 18:53402867-53402867	skin	malignant_melanoma	Substitution - Missense
c.4270G>T; p.D1424Y; 18:53530579-53530579	prostate	adenoma	Substitution - Missense
c.2542G>T; p.V848L; 18:53391741-53391741	breast	carcinoma	Substitution - Missense
c.1983A>G; p.R661R; 18:53305649-53305649	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.757G>T; p.E253*; 18:52923766-52923766	breast	carcinoma	Substitution - Nonsense
c.3282G>A; p.K1094K; 18:53450552-53450552	skin	malignant_melanoma	Substitution - coding silent
c.3674C>A; p.A1225D; 18:53467948-53467948	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.310C>T; p.H104Y; 18:52752272-52752272	skin	malignant_melanoma	Substitution - Missense
c.2276T>C; p.I759T; 18:53339824-53339824	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1994C>T; p.T665M; 18:53305660-53305660	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2969T>C; p.I990T; 18:53410485-53410485	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3181G>A; p.G1061S; 18:53435161-53435161	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1286C>A; p.P429H; 18:53157380-53157380	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.990G>A; p.P330P; 18:53063309-53063309	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1863G>T; p.V621V; 18:53215549-53215549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.80T>G; p.L27R; 18:52340867-52340867	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2842C>T; p.P948S; 18:53402800-53402800	skin	malignant_melanoma	Substitution - Missense
c.3258G>A; p.P1086P; 18:53450528-53450528	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.763A>G; p.K255E; 18:52923772-52923772	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3803C>T; p.P1268L; 18:53486863-53486863	skin	malignant_melanoma	Substitution - Missense
c.1529C>T; p.P510L; 18:53179072-53179072	large_intestine; colon	adenoma	Substitution - Missense
c.3496G>A; p.E1166K; 18:53459335-53459335	skin	malignant_melanoma	Substitution - Missense
c.3154A>T; p.N1052Y; 18:53416147-53416147	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3426G>A; p.K1142K; 18:53459265-53459265	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.389G>A; p.R130Q; 18:52752351-52752351	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1847T>C; p.V616A; 18:53207803-53207803	liver	carcinoma	Substitution - Missense
c.389G>A; p.R130Q; 18:52752351-52752351	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1364C>T; p.A455V; 18:53157458-53157458	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.365G>A; p.G122E; 18:52752327-52752327	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.389G>A; p.R130Q; 18:52752351-52752351	pancreas	carcinoma	Substitution - Missense
c.1364C>T; p.A455V; 18:53157458-53157458	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3233C>T; p.P1078L; 18:53450503-53450503	NS	malignant_melanoma	Substitution - Missense
c.1638T>C; p.I546I; 18:53205280-53205280	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.365G>A; p.G122E; 18:52752327-52752327	skin	malignant_melanoma	Substitution - Missense
c.1847T>C; p.V616A; 18:53207803-53207803	liver	carcinoma	Substitution - Missense
c.365G>A; p.G122E; 18:52752327-52752327	NS	malignant_melanoma	Substitution - Missense
c.1021T>C; p.Y341H; 18:53063340-53063340	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1141G>A; p.G381R; 18:53066046-53066046	skin	malignant_melanoma	Substitution - Missense
c.4083C>T; p.V1361V; 18:53499482-53499482	thyroid	carcinoma; anaplastic_carcinoma	Substitution - coding silent
c.1452C>T; p.S484S; 18:53178995-53178995	skin; shoulder	malignant_melanoma	Substitution - coding silent
c.3046A>G; p.T1016A; 18:53410562-53410562	liver	carcinoma	Substitution - Missense
c.3308T>C; p.V1103A; 18:53450578-53450578	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3046A>G; p.T1016A; 18:53410562-53410562	liver	carcinoma	Substitution - Missense
c.1383T>C; p.T461T; 18:53157477-53157477	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1383T>C; p.T461T; 18:53157477-53157477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1652C>T; p.P551L; 18:53205294-53205294	central_nervous_system; brain	glioma	Substitution - Missense
c.3046A>G; p.T1016A; 18:53410562-53410562	liver	carcinoma	Substitution - Missense
c.2566A>G; p.T856A; 18:53391765-53391765	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1021T>C; p.Y341H; 18:53063340-53063340	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.544C>T; p.P182S; 18:52906175-52906175	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4240G>A; p.E1414K; 18:53526745-53526745	skin	malignant_melanoma	Substitution - Missense
c.4334C>A; p.S1445*; 18:53530643-53530643	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.808A>C; p.S270R; 18:52923817-52923817	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.826G>A; p.G276S; 18:52923835-52923835	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1292C>A; p.A431D; 18:53157386-53157386	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3459T>C; p.L1153L; 18:53459298-53459298	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1469G>A; p.G490E; 18:53179012-53179012	skin	malignant_melanoma	Substitution - Missense
c.2539C>A; p.P847T; 18:53391738-53391738	skin	malignant_melanoma	Substitution - Missense
c.1738G>A; p.G580R; 18:53207694-53207694	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1469G>A; p.G490E; 18:53179012-53179012	skin	malignant_melanoma	Substitution - Missense
c.4234C>G; p.P1412A; 18:53526739-53526739	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3619+2T>C; p.?; 18:53459460-53459460	NS	NS	Unknown
c.562C>A; p.R188R; 18:52906193-52906193	breast	carcinoma	Substitution - coding silent
c.2877G>T; p.K959N; 18:53402835-53402835	liver	carcinoma	Substitution - Missense
c.3190C>T; p.P1064S; 18:53435170-53435170	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3847C>A; p.P1283T; 18:53486907-53486907	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2821G>A; p.E941K; 18:53397440-53397440	skin; trunk	malignant_melanoma	Substitution - Missense
c.2821G>A; p.E941K; 18:53397440-53397440	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3042T>C; p.L1014L; 18:53410558-53410558	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1262-1G>A; p.?; 18:53157355-53157355	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.988C>A; p.P330T; 18:53063307-53063307	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.704G>C; p.G235A; 18:52923713-52923713	breast	carcinoma	Substitution - Missense
c.2640T>A; p.L880L; 18:53391839-53391839	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.667G>A; p.G223R; 18:52906298-52906298	skin; upper_back	malignant_melanoma	Substitution - Missense
c.917G>A; p.G306E; 18:52925302-52925302	breast	carcinoma	Substitution - Missense
c.2182C>A; p.Q728K; 18:53339730-53339730	pancreas	carcinoma	Substitution - Missense
c.3275C>T; p.P1092L; 18:53450545-53450545	skin	malignant_melanoma	Substitution - Missense
c.126C>T; p.F42F; 18:52752088-52752088	skin	malignant_melanoma	Substitution - coding silent
c.1381A>G; p.T461A; 18:53157475-53157475	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1764G>A; p.L588L; 18:53207720-53207720	skin	malignant_melanoma	Substitution - coding silent
c.4251C>A; p.A1417A; 18:53526756-53526756	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1958G>A; p.G653E; 18:53305624-53305624	skin	malignant_melanoma	Substitution - Missense
c.3927A>G; p.Q1309Q; 18:53499326-53499326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1378C>G; p.Q460E; 18:53157472-53157472	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.390G>T; p.R130R; 18:52752352-52752352	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.1958G>A; p.G653E; 18:53305624-53305624	skin	malignant_melanoma	Substitution - Missense
c.3412G>A; p.A1138T; 18:53459251-53459251	breast	carcinoma	Substitution - Missense
c.3676G>C; p.A1226P; 18:53467950-53467950	liver	carcinoma	Substitution - Missense
c.3899-2A>G; p.?; 18:53499296-53499296	lung	carcinoma; adenocarcinoma	Unknown
c.757G>A; p.E253K; 18:52923766-52923766	skin	malignant_melanoma	Substitution - Missense
c.1419-2A>T; p.?; 18:53178960-53178960	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.2780G>A; p.R927K; 18:53397399-53397399	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1418G>A; p.R473K; 18:53157512-53157512	skin	malignant_melanoma	Substitution - Missense
c.2632G>A; p.V878M; 18:53391831-53391831	skin	malignant_melanoma	Substitution - Missense
c.1807C>T; p.R603C; 18:53207763-53207763	skin	malignant_melanoma	Substitution - Missense
c.1532G>A; p.G511E; 18:53179075-53179075	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1807C>T; p.R603C; 18:53207763-53207763	thyroid	carcinoma	Substitution - Missense
c.1807C>T; p.R603C; 18:53207763-53207763	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1807C>T; p.R603C; 18:53207763-53207763	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.186C>T; p.S62S; 18:52752148-52752148	skin	malignant_melanoma	Substitution - coding silent
c.1785T>C; p.S595S; 18:53207741-53207741	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.186C>T; p.S62S; 18:52752148-52752148	skin	malignant_melanoma	Substitution - coding silent
c.186C>T; p.S62S; 18:52752148-52752148	breast	carcinoma	Substitution - coding silent
c.1785T>C; p.S595S; 18:53207741-53207741	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1785T>C; p.S595S; 18:53207741-53207741	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3148A>C; p.M1050L; 18:53416141-53416141	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1132C>T; p.Q378*; 18:53063451-53063451	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.412G>T; p.G138*; 18:52752374-52752374	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2177C>T; p.P726L; 18:53339725-53339725	skin	malignant_melanoma	Substitution - Missense
c.1132C>T; p.Q378*; 18:53063451-53063451	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3148A>C; p.M1050L; 18:53416141-53416141	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2608C>T; p.P870S; 18:53391807-53391807	skin	malignant_melanoma	Substitution - Missense
c.901A>G; p.T301A; 18:52925286-52925286	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3741C>T; p.V1247V; 18:53486801-53486801	skin	malignant_melanoma	Substitution - coding silent
c.2251C>A; p.P751T; 18:53339799-53339799	thyroid	carcinoma	Substitution - Missense
c.1183G>A; p.E395K; 18:53066088-53066088	skin	malignant_melanoma	Substitution - Missense
c.2100A>C; p.T700T; 18:53322093-53322093	liver	carcinoma	Substitution - coding silent
c.644G>A; p.R215Q; 18:52906275-52906275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.644G>A; p.R215Q; 18:52906275-52906275	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3367C>T; p.R1123*; 18:53450637-53450637	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1451C>T; p.S484F; 18:53178994-53178994	skin	malignant_melanoma	Substitution - Missense
c.644G>A; p.R215Q; 18:52906275-52906275	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2184A>G; p.Q728Q; 18:53339732-53339732	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.2290G>C; p.V764L; 18:53339838-53339838	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1220G>A; p.G407E; 18:53066125-53066125	skin	malignant_melanoma	Substitution - Missense
c.3809G>A; p.C1270Y; 18:53486869-53486869	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2211G>A; p.Q737Q; 18:53339759-53339759	skin	malignant_melanoma	Substitution - coding silent
c.4232A>C; p.K1411T; 18:53526737-53526737	pancreas	carcinoma; adenocarcinoma	Substitution - Missense
c.2040G>T; p.W680C; 18:53305706-53305706	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3755C>T; p.P1252L; 18:53486815-53486815	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3435G>A; p.Q1145Q; 18:53459274-53459274	skin	malignant_melanoma	Substitution - coding silent
c.1541C>A; p.S514Y; 18:53179084-53179084	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4255-1G>A; p.?; 18:53530563-53530563	lung	carcinoma; adenocarcinoma	Unknown
c.2423T>C; p.L808P; 18:53386106-53386106	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1164T>A; p.L388L; 18:53066069-53066069	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1369G>A; p.G457R; 18:53157463-53157463	skin	malignant_melanoma	Substitution - Missense
c.1182T>G; p.D394E; 18:53066087-53066087	skin	malignant_melanoma	Substitution - Missense
c.338G>C; p.G113A; 18:52752300-52752300	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4224G>T; p.E1408D; 18:53526729-53526729	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1675C>A; p.Q559K; 18:53205317-53205317	breast	carcinoma	Substitution - Missense
c.1274C>T; p.S425F; 18:53157368-53157368	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.142G>C; p.D48H; 18:52752104-52752104	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.388C>T; p.R130W; 18:52752350-52752350	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.388C>T; p.R130W; 18:52752350-52752350	pancreas	carcinoma	Substitution - Missense
c.3486G>A; p.M1162I; 18:53459325-53459325	skin	malignant_melanoma	Substitution - Missense
c.4137G>A; p.V1379V; 18:53526642-53526642	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.164G>A; p.G55E; 18:52752126-52752126	skin; upper_back	malignant_melanoma	Substitution - Missense
c.164G>A; p.G55E; 18:52752126-52752126	skin	malignant_melanoma	Substitution - Missense
c.2868G>A; p.R956R; 18:53402826-53402826	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.164G>A; p.G55E; 18:52752126-52752126	skin	malignant_melanoma	Substitution - Missense
c.164G>A; p.G55E; 18:52752126-52752126	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.140C>A; p.S47Y; 18:52752102-52752102	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.164G>A; p.G55E; 18:52752126-52752126	skin; arm	malignant_melanoma	Substitution - Missense
c.2507C>T; p.S836L; 18:53391706-53391706	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4077G>A; p.P1359P; 18:53499476-53499476	skin	malignant_melanoma	Substitution - coding silent
c.1794C>A; p.F598L; 18:53207750-53207750	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1794C>A; p.F598L; 18:53207750-53207750	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1877C>T; p.P626L; 18:53215563-53215563	liver	carcinoma	Substitution - Missense
c.1242G>A; p.Q414Q; 18:53066147-53066147	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4077G>A; p.P1359P; 18:53499476-53499476	skin	malignant_melanoma	Substitution - coding silent
c.1594G>A; p.E532K; 18:53205236-53205236	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2392G>A; p.A798T; 18:53386075-53386075	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4077G>A; p.P1359P; 18:53499476-53499476	skin	malignant_melanoma	Substitution - coding silent
c.4077G>A; p.P1359P; 18:53499476-53499476	skin	malignant_melanoma	Substitution - coding silent
c.2382C>T; p.I794I; 18:53386065-53386065	skin	malignant_melanoma	Substitution - coding silent
c.456C>G; p.F152L; 18:52906087-52906087	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.176T>C; p.L59P; 18:52752138-52752138	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.656G>A; p.S219N; 18:52906287-52906287	skin	malignant_melanoma	Substitution - Missense
c.1678G>A; p.G560S; 18:53205320-53205320	ovary	other; neoplasm	Substitution - Missense
c.761G>A; p.G254E; 18:52923770-52923770	skin; trunk	malignant_melanoma	Substitution - Missense
c.2428G>A; p.E810K; 18:53386111-53386111	skin	malignant_melanoma	Substitution - Missense
c.2436C>T; p.A812A; 18:53386119-53386119	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.70A>T; p.S24C; 18:52340857-52340857	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.766G>A; p.D256N; 18:52923775-52923775	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1782T>A; p.Y594*; 18:53207738-53207738	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.668G>A; p.G223E; 18:52906299-52906299	skin; mucosal	malignant_melanoma	Substitution - Missense
c.668G>A; p.G223E; 18:52906299-52906299	skin	malignant_melanoma	Substitution - Missense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]