| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1630 |
Name | DCC |
Synonymous | CRC18|CRCR1|IGDCC1|MRMV1|NTN1R1;DCC netrin 1 receptor;DCC;DCC netrin 1 receptor |
Definition | colorectal cancer suppressor|colorectal tumor suppressor|deleted in colorectal cancer protein|deleted in colorectal carcinoma|immunoglobulin superfamily DCC subclass member 1|immunoglobulin superfamily, DCC subclass, member 1|netrin receptor DCC|tumor sup |
Position | 18q21.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
DCC(h) + Siah-2(m) <==> DCC(h):Siah-2(m) (binding) | DCC(h) + Siah-2(h) <==> DCC(h):Siah-2(h) (binding) | Siah1(h) --/ DCC(h) (degradation) | Siah-2(h) --/ DCC(h) (degradation) | DCC(h) --> DCC(h) (expression). | DCC(h) --> DCC(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
94 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 299 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 318 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 478 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 628 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 702 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr18 |
Promoter: 48119069 - 48121069 | GoldenGate_Methylation_Cancer_Panel_I |
chr18 |
Promoter: 48119069 - 48121069 | GSE27584 |
chr18 |
Promoter: 48119069 - 48121069 | PMID:12374684 |
chr18 |
Promoter: 48119069 - 48121069 | PMID:17018594 |