Entrez Gene

Basic Information
Gene ID	2316
Name	FLNA
Synonymous	filamin A, alpha;FLNA;filamin A, alpha
Definition	actin binding protein 280\|alpha-filamin\|endothelial actin-binding protein\|filamin-1\|filamin-A\|non-muscle filamin
Position	Xq28
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

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We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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The non-synonymous mutational pattern in 17 major cancer types.

The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

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The ratio of the loss-of-function mutations over missense mutations is 0.06.

The copy number variations for various cancers

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There is no record for FLNA

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.3679G>A; p.G1227R; 23:154360116-154360116	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3679G>A; p.G1227R; 23:154360116-154360116	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3679G>A; p.G1227R; 23:154360116-154360116	central_nervous_system; brain	glioma	Substitution - Missense
c.7741G>C; p.D2581H; 23:154349377-154349377	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1314C>T; p.G438G; 23:154366139-154366139	breast	carcinoma	Substitution - coding silent
c.4866C>T; p.Y1622Y; 23:154357513-154357513	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5054C>T; p.T1685M; 23:154354988-154354988	skin	malignant_melanoma	Substitution - Missense
c.902G>A; p.R301Q; 23:154366817-154366817	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1290A>G; p.V430V; 23:154366163-154366163	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6019G>A; p.V2007M; 23:154353299-154353299	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2574C>A; p.P858P; 23:154362324-154362324	thyroid	other; neoplasm	Substitution - coding silent
c.664G>A; p.V222I; 23:154367697-154367697	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.7920C>T; p.S2640S; 23:154348873-154348873	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3377A>G; p.Y1126C; 23:154360418-154360418	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.664G>A; p.V222I; 23:154367697-154367697	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1310G>A; p.R437Q; 23:154366143-154366143	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1904A>G; p.Y635C; 23:154364644-154364644	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2482C>T; p.R828C; 23:154362501-154362501	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6862delC; p.R2288fs*58; 23:154351929-154351929	breast	carcinoma	Deletion - Frameshift
c.7379G>A; p.G2460D; 23:154349822-154349822	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2836G>T; p.G946C; 23:154361778-154361778	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6716A>G; p.H2239R; 23:154352234-154352234	skin	malignant_melanoma	Substitution - Missense
c.6466G>A; p.V2156I; 23:154352589-154352589	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4655G>T; p.G1552V; 23:154358299-154358299	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2064C>T; p.A688A; 23:154364331-154364331	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.4142G>T; p.R1381M; 23:154359484-154359484	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4344G>A; p.A1448A; 23:154359114-154359114	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5160C>T; p.Y1720Y; 23:154354882-154354882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4363G>A; p.G1455R; 23:154359095-154359095	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.6424G>T; p.E2142*; 23:154352631-154352631	pancreas	carcinoma	Substitution - Nonsense
c.4909G>A; p.V1637M; 23:154357470-154357470	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5599C>T; p.H1867Y; 23:154354002-154354002	skin	malignant_melanoma	Substitution - Missense
c.3877G>A; p.V1293I; 23:154359834-154359834	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6299G>T; p.G2100V; 23:154352852-154352852	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.6299G>T; p.G2100V; 23:154352852-154352852	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4506C>T; p.N1502N; 23:154358537-154358537	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.831C>T; p.P277P; 23:154367434-154367434	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1764C>T; p.G588G; 23:154364885-154364885	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2451C>T; p.P817P; 23:154362532-154362532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1764C>T; p.G588G; 23:154364885-154364885	liver	carcinoma	Substitution - coding silent
c.2451C>T; p.P817P; 23:154362532-154362532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3393C>T; p.P1131P; 23:154360402-154360402	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2327G>T; p.G776V; 23:154362738-154362738	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6710delG; p.G2237fs*109; 23:154352240-154352240	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.7055C>A; p.S2352Y; 23:154351010-154351010	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.246G>T; p.E82D; 23:154371000-154371000	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.485_487delAGG; p.E162delE; 23:154367977-154367979	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.485_487delAGG; p.E162delE; 23:154367977-154367979	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.485_487delAGG; p.E162delE; 23:154367977-154367979	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.485_487delAGG; p.E162delE; 23:154367977-154367979	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.485_487delAGG; p.E162delE; 23:154367977-154367979	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.485_487delAGG; p.E162delE; 23:154367977-154367979	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.4699G>A; p.E1567K; 23:154358255-154358255	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.7574A>C; p.H2525P; 23:154349544-154349544	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3076delG; p.A1026fs*20; 23:154361439-154361439	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.6219C>T; p.R2073R; 23:154353008-154353008	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3940G>A; p.D1314N; 23:154359771-154359771	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6219C>T; p.R2073R; 23:154353008-154353008	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.6752C>T; p.A2251V; 23:154352198-154352198	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6007C>T; p.R2003C; 23:154353311-154353311	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4868G>T; p.G1623V; 23:154357511-154357511	breast	carcinoma	Substitution - Missense
c.4495G>A; p.V1499M; 23:154358548-154358548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6602G>A; p.R2201H; 23:154352348-154352348	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.6297C>T; p.D2099D; 23:154352854-154352854	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.4369G>A; p.G1457S; 23:154359089-154359089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1996G>A; p.A666T; 23:154364552-154364552	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3420C>T; p.F1140F; 23:154360375-154360375	skin	malignant_melanoma	Substitution - coding silent
c.1582G>A; p.V528M; 23:154365245-154365245	breast	carcinoma	Substitution - Missense
c.1996G>A; p.A666T; 23:154364552-154364552	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1052C>A; p.T351K; 23:154366575-154366575	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1996G>A; p.A666T; 23:154364552-154364552	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1897G>A; p.V633M; 23:154364651-154364651	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5683G>T; p.E1895*; 23:154353918-154353918	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.5967G>A; p.P1989P; 23:154353351-154353351	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1423G>T; p.G475C; 23:154366030-154366030	ovary	other; neoplasm	Substitution - Missense
c.3795T>C; p.I1265I; 23:154360000-154360000	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3369C>T; p.S1123S; 23:154360426-154360426	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5967G>A; p.P1989P; 23:154353351-154353351	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.620C>T; p.P207L; 23:154367844-154367844	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6298G>A; p.G2100R; 23:154352853-154352853	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5062G>C; p.V1688L; 23:154354980-154354980	ovary	other; neoplasm	Substitution - Missense
c.1165C>A; p.P389T; 23:154366371-154366371	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1008C>T; p.N336N; 23:154366619-154366619	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.70C>A; p.R24R; 23:154371176-154371176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2472C>T; p.F824F; 23:154362511-154362511	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5146delC; p.Q1716fs*23; 23:154354896-154354896	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.7510C>T; p.P2504S; 23:154349691-154349691	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.5146delC; p.Q1716fs*23; 23:154354896-154354896	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2516C>T; p.T839M; 23:154362467-154362467	thyroid	carcinoma	Substitution - Missense
c.2516C>T; p.T839M; 23:154362467-154362467	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1359C>T; p.V453V; 23:154366094-154366094	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2839G>A; p.V947I; 23:154361775-154361775	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3648G>A; p.T1216T; 23:154360147-154360147	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4483G>A; p.E1495K; 23:154358560-154358560	skin	malignant_melanoma	Substitution - Missense
c.6570C>T; p.I2190I; 23:154352380-154352380	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2033G>A; p.R678H; 23:154364362-154364362	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2033G>A; p.R678H; 23:154364362-154364362	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5289C>T; p.Y1763Y; 23:154354640-154354640	pancreas	carcinoma	Substitution - coding silent
c.3990C>G; p.S1330S; 23:154359636-154359636	liver	carcinoma	Substitution - coding silent
c.3990C>G; p.S1330S; 23:154359636-154359636	liver	carcinoma	Substitution - coding silent
c.3882G>T; p.K1294N; 23:154359829-154359829	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1765G>A; p.G589S; 23:154364884-154364884	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1765G>A; p.G589S; 23:154364884-154364884	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1526G>T; p.G509V; 23:154365390-154365390	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.956A>G; p.Y319C; 23:154366763-154366763	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4288G>A; p.G1430S; 23:154359261-154359261	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3256G>A; p.A1086T; 23:154360539-154360539	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2058T>G; p.G686G; 23:154364337-154364337	breast	carcinoma	Substitution - coding silent
c.850G>A; p.A284T; 23:154367415-154367415	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.846G>A; p.K282K; 23:154367419-154367419	breast	carcinoma; ductal_carcinoma	Substitution - coding silent
c.5097C>A; p.D1699E; 23:154354945-154354945	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6583A>G; p.N2195D; 23:154352367-154352367	skin	malignant_melanoma	Substitution - Missense
c.1528G>A; p.A510T; 23:154365388-154365388	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.7943G>T; p.*2648L; 23:154348850-154348850	skin	malignant_melanoma	Nonstop extension
c.803A>G; p.K268R; 23:154367462-154367462	liver	carcinoma	Substitution - Missense
c.803A>G; p.K268R; 23:154367462-154367462	liver	carcinoma	Substitution - Missense
c.2638C>A; p.P880T; 23:154362260-154362260	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3572C>T; p.A1191V; 23:154360223-154360223	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3086G>A; p.S1029N; 23:154361429-154361429	liver	carcinoma	Substitution - Missense
c.4781C>A; p.T1594K; 23:154357598-154357598	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3199C>T; p.P1067S; 23:154361316-154361316	skin	malignant_melanoma	Substitution - Missense
c.3086G>A; p.S1029N; 23:154361429-154361429	liver	carcinoma	Substitution - Missense
c.7632C>T; p.A2544A; 23:154349486-154349486	skin	malignant_melanoma	Substitution - coding silent
c.5273C>A; p.A1758D; 23:154354656-154354656	thyroid	other; neoplasm	Substitution - Missense
c.7062A>G; p.A2354A; 23:154351003-154351003	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1813G>A; p.D605N; 23:154364836-154364836	breast	carcinoma	Substitution - Missense
c.2023-2A>C; p.?; 23:154364374-154364374	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.3368C>T; p.S1123F; 23:154360427-154360427	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5874G>A; p.M1958I; 23:154353444-154353444	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5874G>A; p.M1958I; 23:154353444-154353444	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4758T>C; p.D1586D; 23:154357621-154357621	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2623G>A; p.V875M; 23:154362275-154362275	skin	malignant_melanoma	Substitution - Missense
c.7928G>A; p.R2643H; 23:154348865-154348865	pancreas	carcinoma	Substitution - Missense
c.720+9G>T; p.?; 23:154367632-154367632	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Unknown
c.6897C>G; p.V2299V; 23:154351894-154351894	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1996G>T; p.A666S; 23:154364552-154364552	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5881T>C; p.S1961P; 23:154353437-154353437	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.7901delA; p.D2634fs*>14; 23:154348892-154348892	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.7742A>G; p.D2581G; 23:154349376-154349376	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.7742A>G; p.D2581G; 23:154349376-154349376	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.7636delC; p.Q2546fs*22; 23:154349482-154349482	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4803C>T; p.D1601D; 23:154357576-154357576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1278G>A; p.Q426Q; 23:154366175-154366175	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1065G>A; p.K355K; 23:154366562-154366562	skin	malignant_melanoma	Substitution - coding silent
c.1278G>A; p.Q426Q; 23:154366175-154366175	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.136C>T; p.Q46*; 23:154371110-154371110	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.5833G>T; p.G1945C; 23:154353581-154353581	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4510G>A; p.D1504N; 23:154358533-154358533	breast	carcinoma	Substitution - Missense
c.826C>T; p.R276W; 23:154367439-154367439	central_nervous_system; brain	glioma	Substitution - Missense
c.5913C>G; p.I1971M; 23:154353405-154353405	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5076T>C; p.D1692D; 23:154354966-154354966	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2632G>A; p.E878K; 23:154362266-154362266	breast	carcinoma	Substitution - Missense
c.6408C>T; p.G2136G; 23:154352647-154352647	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2504C>T; p.T835M; 23:154362479-154362479	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.553A>G; p.I185V; 23:154367911-154367911	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6445C>T; p.R2149W; 23:154352610-154352610	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.3597G>A; p.S1199S; 23:154360198-154360198	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.5491C>T; p.R1831W; 23:154354217-154354217	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5069C>T; p.T1690M; 23:154354973-154354973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6229T>A; p.Y2077N; 23:154352922-154352922	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2325C>T; p.Y775Y; 23:154362740-154362740	breast	carcinoma	Substitution - coding silent
c.7515C>T; p.Y2505Y; 23:154349686-154349686	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.553A>G; p.I185V; 23:154367911-154367911	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.7668C>T; p.D2556D; 23:154349450-154349450	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.1508T>A; p.F503Y; 23:154365408-154365408	central_nervous_system; brain	glioma	Substitution - Missense
c.506A>C; p.K169T; 23:154367958-154367958	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2510A>G; p.K837R; 23:154362473-154362473	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.206C>T; p.T69M; 23:154371040-154371040	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1114G>T; p.V372L; 23:154366422-154366422	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.5387C>T; p.P1796L; 23:154354410-154354410	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5696C>T; p.S1899F; 23:154353718-154353718	skin	malignant_melanoma	Substitution - Missense
c.6213T>C; p.D2071D; 23:154353014-154353014	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.6317A>C; p.Y2106S; 23:154352834-154352834	breast	carcinoma	Substitution - Missense
c.739A>G; p.I247V; 23:154367526-154367526	skin	malignant_melanoma	Substitution - Missense
c.2814G>A; p.T938T; 23:154361991-154361991	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4247C>T; p.P1416L; 23:154359302-154359302	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4661G>A; p.G1554E; 23:154358293-154358293	skin; ankle	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.4883C>T; p.P1628L; 23:154357496-154357496	skin	malignant_melanoma	Substitution - Missense
c.2615C>T; p.A872V; 23:154362283-154362283	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.5478C>A; p.G1826G; 23:154354230-154354230	liver	carcinoma	Substitution - coding silent
c.5478C>A; p.G1826G; 23:154354230-154354230	liver	carcinoma	Substitution - coding silent
c.299G>A; p.R100H; 23:154370947-154370947	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4290C>T; p.G1430G; 23:154359259-154359259	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2437G>A; p.G813R; 23:154362546-154362546	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.7053C>T; p.A2351A; 23:154351012-154351012	oesophagus	carcinoma	Substitution - coding silent
c.5917A>T; p.I1973F; 23:154353401-154353401	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.843G>T; p.P281P; 23:154367422-154367422	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2037G>T; p.G679G; 23:154364358-154364358	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.4196A>G; p.K1399R; 23:154359353-154359353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2037G>T; p.G679G; 23:154364358-154364358	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3514C>A; p.R1172R; 23:154360281-154360281	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3514C>A; p.R1172R; 23:154360281-154360281	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.144T>G; p.T48T; 23:154371102-154371102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5995C>T; p.L1999L; 23:154353323-154353323	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1096G>A; p.A366T; 23:154366440-154366440	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1242C>T; p.G414G; 23:154366211-154366211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1923C>T; p.G641G; 23:154364625-154364625	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3904G>T; p.G1302C; 23:154359807-154359807	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.7910T>A; p.I2637N; 23:154348883-154348883	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1637T>C; p.V546A; 23:154365190-154365190	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.7485C>T; p.Y2495Y; 23:154349716-154349716	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.7779G>T; p.G2593G; 23:154349014-154349014	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3353G>T; p.G1118V; 23:154360442-154360442	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5460C>T; p.I1820I; 23:154354248-154354248	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1997C>T; p.A666V; 23:154364551-154364551	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4648G>A; p.A1550T; 23:154358306-154358306	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6175G>A; p.E2059K; 23:154353052-154353052	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4366C>A; p.P1456T; 23:154359092-154359092	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.313G>C; p.E105Q; 23:154370933-154370933	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.7122C>G; p.A2374A; 23:154350943-154350943	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3567C>A; p.G1189G; 23:154360228-154360228	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.781C>A; p.L261M; 23:154367484-154367484	pancreas	carcinoma	Substitution - Missense
c.4224C>T; p.G1408G; 23:154359325-154359325	breast	carcinoma; ductal_carcinoma	Substitution - coding silent
c.4224C>T; p.G1408G; 23:154359325-154359325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1920T>G; p.A640A; 23:154364628-154364628	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.6107C>T; p.P2036L; 23:154353120-154353120	skin	malignant_melanoma	Substitution - Missense
c.7166C>T; p.A2389V; 23:154350198-154350198	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2257A>G; p.S753G; 23:154364045-154364045	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4377C>G; p.S1459R; 23:154359081-154359081	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5132T>C; p.F1711S; 23:154354910-154354910	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1109T>A; p.F370Y; 23:154366427-154366427	breast	carcinoma	Substitution - Missense
c.5132T>C; p.F1711S; 23:154354910-154354910	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.7371G>A; p.A2457A; 23:154349830-154349830	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.429C>A; p.T143T; 23:154368035-154368035	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.151C>T; p.R51C; 23:154371095-154371095	ovary	other; neoplasm	Substitution - Missense
c.7454T>C; p.V2485A; 23:154349747-154349747	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6486C>A; p.L2162L; 23:154352569-154352569	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1179C>T; p.P393P; 23:154366357-154366357	skin	malignant_melanoma	Substitution - coding silent
c.1042C>T; p.P348S; 23:154366585-154366585	skin	malignant_melanoma	Substitution - Missense
c.162C>G; p.N54K; 23:154371084-154371084	ovary	other; neoplasm	Substitution - Missense
c.3699C>G; p.I1233M; 23:154360096-154360096	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.43G>A; p.A15T; 23:154371203-154371203	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4711G>C; p.D1571H; 23:154358243-154358243	breast	carcinoma	Substitution - Missense
c.7900G>A; p.D2634N; 23:154348893-154348893	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4757A>G; p.D1586G; 23:154357622-154357622	breast	carcinoma	Substitution - Missense
c.7112C>T; p.P2371L; 23:154350953-154350953	skin	malignant_melanoma	Substitution - Missense
c.1695C>A; p.P565P; 23:154364954-154364954	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5364G>C; p.L1788L; 23:154354433-154354433	breast	carcinoma	Substitution - coding silent
c.3932A>G; p.D1311G; 23:154359779-154359779	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3932A>G; p.D1311G; 23:154359779-154359779	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1038C>T; p.Y346Y; 23:154366589-154366589	skin	malignant_melanoma	Substitution - coding silent
c.3154delG; p.V1052fs*19; 23:154361361-154361361	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4773G>A; p.P1591P; 23:154357606-154357606	breast	carcinoma	Substitution - coding silent
c.4465G>A; p.G1489R; 23:154358993-154358993	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1698C>T; p.F566F; 23:154364951-154364951	skin	malignant_melanoma	Substitution - coding silent
c.7360A>T; p.T2454S; 23:154349841-154349841	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4833C>T; p.D1611D; 23:154357546-154357546	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4221C>T; p.D1407D; 23:154359328-154359328	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.5074G>C; p.D1692H; 23:154354968-154354968	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2392G>A; p.E798K; 23:154362673-154362673	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4020G>A; p.V1340V; 23:154359606-154359606	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5033C>T; p.A1678V; 23:154355009-154355009	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2389G>T; p.A797S; 23:154362676-154362676	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1998G>A; p.A666A; 23:154364550-154364550	breast	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2813C>T; p.T938M; 23:154361992-154361992	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1699G>A; p.E567K; 23:154364950-154364950	urinary_tract; bladder	carcinoma	Substitution - Missense
c.216C>T; p.S72S; 23:154371030-154371030	breast	carcinoma	Substitution - coding silent
c.216C>T; p.S72S; 23:154371030-154371030	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1487G>A; p.R496Q; 23:154365429-154365429	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6455C>T; p.S2152L; 23:154352600-154352600	breast	carcinoma	Substitution - Missense
c.504delC; p.K169fs*73; 23:154367960-154367960	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1911G>T; p.P637P; 23:154364637-154364637	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3259C>T; p.R1087C; 23:154360536-154360536	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4142+10C>T; p.?; 23:154359474-154359474	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.271C>G; p.R91G; 23:154370975-154370975	urinary_tract; bladder	carcinoma	Substitution - Missense
c.6008G>A; p.R2003H; 23:154353310-154353310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2202C>A; p.S734S; 23:154364100-154364100	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2695G>T; p.A899S; 23:154362110-154362110	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.6551A>G; p.K2184R; 23:154352399-154352399	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.7194C>T; p.G2398G; 23:154350170-154350170	pancreas	carcinoma	Substitution - coding silent
c.245A>G; p.E82G; 23:154371001-154371001	thyroid	other; neoplasm	Substitution - Missense
c.4903C>T; p.R1635C; 23:154357476-154357476	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.7894T>A; p.W2632R; 23:154348899-154348899	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2955T>A; p.V985V; 23:154361560-154361560	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1807G>T; p.G603W; 23:154364842-154364842	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6047C>T; p.T2016M; 23:154353180-154353180	oesophagus	carcinoma	Substitution - Missense
c.4896C>T; p.Y1632Y; 23:154357483-154357483	thyroid	carcinoma	Substitution - coding silent
c.1807G>T; p.G603W; 23:154364842-154364842	breast	carcinoma; ductolobular_carcinoma	Substitution - Missense
c.1228+3G>T; p.?; 23:154366305-154366305	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Unknown
c.5344G>C; p.G1782R; 23:154354453-154354453	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.7450C>T; p.R2484C; 23:154349751-154349751	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.6624C>T; p.G2208G; 23:154352326-154352326	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3337G>A; p.E1113K; 23:154360458-154360458	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.7405C>T; p.P2469S; 23:154349796-154349796	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3822C>G; p.A1274A; 23:154359889-154359889	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1609G>A; p.V537M; 23:154365218-154365218	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2520C>T; p.P840P; 23:154362463-154362463	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2104G>A; p.G702S; 23:154364291-154364291	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.2132T>C; p.V711A; 23:154364263-154364263	breast	carcinoma	Substitution - Missense
c.1480G>C; p.G494R; 23:154365436-154365436	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3568A>G; p.S1190G; 23:154360227-154360227	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5055G>A; p.T1685T; 23:154354987-154354987	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.6601C>T; p.R2201C; 23:154352349-154352349	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3161G>C; p.G1054A; 23:154361354-154361354	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2860G>T; p.D954Y; 23:154361754-154361754	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1545G>T; p.L515L; 23:154365371-154365371	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4811A>T; p.Y1604F; 23:154357568-154357568	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.810G>A; p.K270K; 23:154367455-154367455	skin	malignant_melanoma	Substitution - coding silent
c.5634A>T; p.G1878G; 23:154353967-154353967	breast	carcinoma	Substitution - coding silent
c.7088C>T; p.A2363V; 23:154350977-154350977	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4524C>A; p.T1508T; 23:154358519-154358519	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4010G>T; p.G1337V; 23:154359616-154359616	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.7669G>A; p.A2557T; 23:154349449-154349449	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.7825G>A; p.V2609M; 23:154348968-154348968	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4891C>T; p.P1631S; 23:154357488-154357488	skin	malignant_melanoma	Substitution - Missense
c.1466G>A; p.G489D; 23:154365450-154365450	liver	carcinoma	Substitution - Missense
c.1466G>A; p.G489D; 23:154365450-154365450	liver	carcinoma	Substitution - Missense
c.2762G>A; p.R921Q; 23:154362043-154362043	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1932C>T; p.A644A; 23:154364616-154364616	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1599G>T; p.L533L; 23:154365228-154365228	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.5229G>T; p.G1743G; 23:154354700-154354700	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.5876G>A; p.R1959H; 23:154353442-154353442	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.5876G>A; p.R1959H; 23:154353442-154353442	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5164A>G; p.I1722V; 23:154354878-154354878	breast	carcinoma	Substitution - Missense
c.5817T>C; p.N1939N; 23:154353597-154353597	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.7218C>T; p.F2406F; 23:154350146-154350146	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4330G>A; p.D1444N; 23:154359128-154359128	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1223C>T; p.T408M; 23:154366313-154366313	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4808C>T; p.T1603M; 23:154357571-154357571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.759C>T; p.D253D; 23:154367506-154367506	pancreas	carcinoma	Substitution - coding silent
c.999C>T; p.T333T; 23:154366628-154366628	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3285C>T; p.A1095A; 23:154360510-154360510	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4259G>C; p.G1420A; 23:154359290-154359290	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6653G>A; p.G2218D; 23:154352297-154352297	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1026C>T; p.F342F; 23:154366601-154366601	skin	malignant_melanoma	Substitution - coding silent
c.4710C>A; p.I1570I; 23:154358244-154358244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3972C>T; p.Y1324Y; 23:154359739-154359739	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.7610C>T; p.S2537F; 23:154349508-154349508	skin	malignant_melanoma	Substitution - Missense
c.4710C>T; p.I1570I; 23:154358244-154358244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4452G>T; p.Q1484H; 23:154359006-154359006	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2488G>T; p.D830Y; 23:154362495-154362495	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1581C>T; p.R527R; 23:154365246-154365246	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5241G>A; p.S1747S; 23:154354688-154354688	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1167C>T; p.P389P; 23:154366369-154366369	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1581C>T; p.R527R; 23:154365246-154365246	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.792C>T; p.F264F; 23:154367473-154367473	skin	malignant_melanoma	Substitution - coding silent
c.5347C>T; p.L1783L; 23:154354450-154354450	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.732C>G; p.P244P; 23:154367533-154367533	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.6963C>T; p.F2321F; 23:154351641-154351641	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.7134C>A; p.C2378*; 23:154350931-154350931	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1399C>T; p.R467C; 23:154366054-154366054	skin	malignant_melanoma	Substitution - Missense
c.7017C>T; p.S2339S; 23:154351587-154351587	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1716C>T; p.T572T; 23:154364933-154364933	thyroid	carcinoma	Substitution - coding silent
c.3478G>A; p.A1160T; 23:154360317-154360317	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.7806_7807GG>TT; p.E2602_E2603>D*; 23:154348986-154348987	lung; right_upper_lobe	carcinoma; adenocarcinoma	Complex - compound substitution
c.3990C>T; p.S1330S; 23:154359636-154359636	NS	malignant_melanoma	Substitution - coding silent
c.1487G>C; p.R496P; 23:154365429-154365429	ovary	other; neoplasm	Substitution - Missense
c.3990C>T; p.S1330S; 23:154359636-154359636	NS	malignant_melanoma	Substitution - coding silent
c.3544C>T; p.Q1182*; 23:154360251-154360251	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.411C>T; p.I137I; 23:154368053-154368053	skin	malignant_melanoma	Substitution - coding silent
c.6018C>T; p.H2006H; 23:154353300-154353300	liver	carcinoma	Substitution - coding silent
c.6018C>T; p.H2006H; 23:154353300-154353300	liver	carcinoma	Substitution - coding silent
c.4164G>C; p.L1388L; 23:154359385-154359385	breast	carcinoma	Substitution - coding silent
c.2399G>C; p.G800A; 23:154362666-154362666	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.587G>A; p.R196Q; 23:154367877-154367877	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1191C>T; p.I397I; 23:154366345-154366345	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2848A>C; p.T950P; 23:154361766-154361766	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1995C>T; p.D665D; 23:154364553-154364553	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2630C>T; p.A877V; 23:154362268-154362268	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.7350C>A; p.F2450L; 23:154349851-154349851	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1327C>T; p.R443C; 23:154366126-154366126	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4050C>T; p.T1350T; 23:154359576-154359576	breast	carcinoma	Substitution - coding silent
c.2543T>G; p.I848S; 23:154362440-154362440	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2404+7C>T; p.?; 23:154362654-154362654	pancreas	carcinoma	Unknown
c.3636C>T; p.H1212H; 23:154360159-154360159	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3001C>G; p.Q1001E; 23:154361514-154361514	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2103C>T; p.H701H; 23:154364292-154364292	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.5070G>T; p.T1690T; 23:154354972-154354972	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2358C>T; p.A786A; 23:154362707-154362707	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2825A>G; p.Q942R; 23:154361980-154361980	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.402G>A; p.L134L; 23:154368062-154368062	breast	carcinoma	Substitution - coding silent
c.561C>A; p.N187K; 23:154367903-154367903	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.985G>A; p.E329K; 23:154366734-154366734	breast	carcinoma	Substitution - Missense
c.3718G>A; p.V1240M; 23:154360077-154360077	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3718G>A; p.V1240M; 23:154360077-154360077	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.439C>T; p.H147Y; 23:154368025-154368025	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.6228C>A; p.G2076G; 23:154352923-154352923	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2252G>A; p.G751D; 23:154364050-154364050	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5198A>G; p.N1733S; 23:154354844-154354844	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4060G>A; p.D1354N; 23:154359566-154359566	oesophagus	carcinoma	Substitution - Missense
c.893T>G; p.V298G; 23:154366826-154366826	breast	carcinoma	Substitution - Missense
c.3637G>A; p.G1213S; 23:154360158-154360158	skin	malignant_melanoma	Substitution - Missense
c.33C>T; p.S11S; 23:154371213-154371213	thyroid	carcinoma	Substitution - coding silent
c.1872C>T; p.D624D; 23:154364676-154364676	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1771G>A; p.V591I; 23:154364878-154364878	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1771G>A; p.V591I; 23:154364878-154364878	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4899C>T; p.R1633R; 23:154357480-154357480	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5437G>T; p.G1813C; 23:154354271-154354271	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3253C>T; p.P1085S; 23:154360542-154360542	skin	malignant_melanoma	Substitution - Missense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]