| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 2316 |
Name | FLNA |
Synonymous | ABP-280|ABPX|CSBS|CVD1|FLN|FLN-A|FLN1|FMD|MNS|NHBP|OPD|OPD1|OPD2|XLVD|XMVD;filamin A, alpha;FLNA;filamin A, alpha |
Definition | actin binding protein 280|alpha-filamin|endothelial actin-binding protein|filamin-1|filamin-A|non-muscle filamin |
Position | Xq28 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
Lnk(h) + ABP-280(h) <==> Lnk(h):ABP-280(h) (binding) | beta3-integrin(h) + ABP-280(h) <==> beta3-integrin(h):ABP-280(h) (binding) | ABP-280(h) + ATP --RSK1(c)--> ABP-280(h){pS2152} + ADP (phosphorylation) | Smad5(m) + ABP-280(h) <==> Smad5(m):ABP-280(h) (binding) | ABP-280(h) + AR-isoform1(h) <==> ABP-280(h):AR-isoform1(h) (binding) | ABP-280(h) + foxc1(h) <==> ABP-280(h):foxc1(h) (binding) | ABP-280(h) + granzymeB(h) <==> ABP-280(h):granzymeB(h) (binding) | ABP-280(h) --> ABP-280-p205(h) + protein remnants (cleavage) | ABP-280(h) --> ABP-280-p95(h) + ABP-280-p110(h) + protein remnants (cleavage) | ABP-280(h) --granzymeB(h)--> ABP-280-p205(h) + protein remnants (cleavage) | ABP-280(h) --granzymeB(h)--> ABP-280-p200(h) + protein remnants (cleavage) | ABP-280(h) --granzymeB(h)--> ABP-280-p110(h) + protein remnants (cleavage) | ABP-280(h) --> ABP-280(h) (translocation) | TLR10(h) + ABP-280(h) <==> TLR10(h):ABP-280(h) (binding) | mGluR7(r) + ABP-280(h) <==> mGluR7(r):ABP-280(h) (binding) | FBLP-1(h) + ABP-280(h) <==> FBLP-1(h):ABP-280(h) (binding) | ABP-280(h) + ASC1(h) <==> ABP-280(h):ASC1(h) (binding) | FLNA(h) --> ABP-280(h) (expression). | ABP-280(h) --> ABP-280(h) (translocation) | ABP-280(h) + Smad5(m.s.) <==> ABP-280(h):Smad5(m.s.) (binding) | ABP-280(h) + Smad1(m.s.) <==> ABP-280(h):Smad1(m.s.) (binding) | ABP-280(h) + Smad2(m.s.) <==> ABP-280(h):Smad2(m.s.) (binding) | ABP-280(h) + Smad4(m.s.) <==> ABP-280(h):Smad4(m.s.) (binding) | ABP-280(h) + Smad6(m.s.) <==> ABP-280(h):Smad6(m.s.) (binding) | ABP-280(h) + foxc1(h) <==> ABP-280(h):foxc1(h) (binding) | FLNA(h) --> ABP-280(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
2 | N-acetylserine. | Swiss-Prot 53.0 | 1047 | Phosphotyrosine. | Swiss-Prot 53.0 | 1084 | Phosphoserine. | Swiss-Prot 53.0 | 1089 | Phosphothreonine. | Swiss-Prot 53.0 | 1459 | Phosphoserine. | Swiss-Prot 53.0 | 1533 | Phosphoserine. | Swiss-Prot 53.0 | 2152 | Phosphoserine. | Swiss-Prot 53.0 | 2284 | Phosphoserine. | Swiss-Prot 53.0 | 2327 | Phosphoserine. | Swiss-Prot 53.0 | 1046 | Phosphotyrosine | 15592455 | Phospho.ELM 6.0 | 1458 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1083 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
There is no record for FLNA | ||