Entrez Gene

Basic Information
Gene ID	2322
Name	FLT3
Synonymous	fms-related tyrosine kinase 3;FLT3;fms-related tyrosine kinase 3
Definition	CD135 antigen\|FL cytokine receptor\|fetal liver kinase 2\|fms-like tyrosine kinase 3\|growth factor receptor tyrosine kinase type III\|receptor-type tyrosine-protein kinase FLT3\|stem cell tyrosine kinase 1
Position	13q12
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.06.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1665T>C; p.I555I; 13:28034340-28034340	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1225C>T; p.H409Y; 13:28037269-28037269	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1108T>C; p.S370P; 13:28048372-28048372	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1791_1792ins?; p.Y597_E598ins26; 13:28034127-28034128	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1791_1792ins?; p.Y597_E598ins26; 13:28034127-28034128	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1652G>A; p.C551Y; 13:28034353-28034353	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1641A>G; p.T547T; 13:28034364-28034364	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1339G>A; p.A447T; 13:28036014-28036014	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myelomonocytic_leukaemia	Substitution - Missense
c.2520_2521insGGATCC; p.S840_N841insGS; 13:28018487-28018488	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1795_1796ins39; p.Y599_D600ins13; 13:28034123-28034124	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2028C>A; p.N676K; 13:28028203-28028203	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1327G>A; p.A443T; 13:28036026-28036026	breast	carcinoma	Substitution - Missense
c.2028C>A; p.N676K; 13:28028203-28028203	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2520_2521insGGATCC; p.S840_N841insGS; 13:28018487-28018488	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.?_?ins?; p.A620_F621ins39; 13:28033968-28033969	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Insertion - In frame
c.500C>T; p.T167I; 13:28052659-28052659	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1670T>C; p.V557A; 13:28034335-28034335	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1670T>C; p.V557A; 13:28034335-28034335	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1670T>C; p.V557A; 13:28034335-28034335	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1670T>C; p.V557A; 13:28034335-28034335	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1670T>C; p.V557A; 13:28034335-28034335	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1794_1795ins30; p.E598_Y599ins10; 13:28034124-28034125	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1780_1781ins21; p.D593_F594insWGYFYVD; 13:28034138-28034139	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1782_1783ins42; p.F594_R595ins14; 13:28034136-28034137	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2411T>G; p.F804C; 13:28023357-28023357	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2726A>G; p.D909G; 13:28015184-28015184	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.2797C>A; p.R933R; 13:28014514-28014514	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2648C>A; p.S883*; 13:28015595-28015595	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2749G>T; p.E917*; 13:28015161-28015161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.449_450CC>TT; p.T150I; 13:28057381-28057382	skin	malignant_melanoma	Substitution - Missense
c.610G>T; p.E204*; 13:28052549-28052549	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1841A>G; p.K614R; 13:28033988-28033988	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1841A>T; p.K614M; 13:28033988-28033988	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.215C>T; p.S72L; 13:28062020-28062020	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1811_1812ins18; p.E604_F605insYDLKWE; 13:28034107-28034108	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2050T>C; p.S684P; 13:28028181-28028181	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.237C>T; p.A79A; 13:28061998-28061998	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - coding silent
c.1879G>A; p.A627T; 13:28033950-28033950	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.971_982del12; p.G326_T329delGYYT; 13:28049438-28049449	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Deletion - In frame
c.1879G>A; p.A627T; 13:28033950-28033950	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1879G>A; p.A627T; 13:28033950-28033950	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1799_1800ins51; p.D600_L601ins17; 13:28034119-28034120	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1879G>A; p.A627T; 13:28033950-28033950	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2525A>G; p.Y842C; 13:28018483-28018483	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2525A>G; p.Y842C; 13:28018483-28018483	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2525A>G; p.Y842C; 13:28018483-28018483	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.192G>C; p.G64G; 13:28062043-28062043	lung	carcinoma; large_cell_carcinoma	Substitution - coding silent
c.192G>C; p.G64G; 13:28062043-28062043	lung	carcinoma; large_cell_carcinoma	Substitution - coding silent
c.1635T>C; p.Y545Y; 13:28034370-28034370	liver	carcinoma	Substitution - coding silent
c.1635T>C; p.Y545Y; 13:28034370-28034370	liver	carcinoma	Substitution - coding silent
c.2654_2753del100; p.G885fs*4; 13:28015157-28015256	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_eosinophilic_leukaemia-hypereosinophilic_syndrome	Deletion - Frameshift
c.1794_1795ins66; p.E598_Y599ins22; 13:28034124-28034125	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2971G>A; p.E991K; 13:28004063-28004063	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.2971G>A; p.E991K; 13:28004063-28004063	skin	malignant_melanoma	Substitution - Missense
c.1761_1762ins114; p.N587_E588ins30; 13:28034157-28034158	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Insertion - In frame
c.1935G>A; p.M645I; 13:28033894-28033894	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDS	Substitution - Missense
c.2508C>A; p.I836I; 13:28018500-28018500	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2508C>A; p.I836I; 13:28018500-28018500	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2917C>T; p.R973*; 13:28004117-28004117	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2158G>A; p.E720K; 13:28027137-28027137	skin	malignant_melanoma	Substitution - Missense
c.1669G>A; p.V557I; 13:28034336-28034336	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.728_729GG>TT; p.R243I; 13:28050108-28050109	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2967G>T; p.Q989H; 13:28004067-28004067	breast	carcinoma	Substitution - Missense
c.1747G>A; p.G583S; 13:28034172-28034172	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.576G>T; p.P192P; 13:28052583-28052583	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1747G>A; p.G583S; 13:28034172-28034172	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1781_1798>12; p.F594_D600>SPPPH; 13:28034121-28034138	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Complex - deletion inframe
c.2789C>G; p.S930*; 13:28014522-28014522	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1879_1880ins113; p.A627fs*22; 13:28033949-28033950	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - Frameshift
c.826C>T; p.H276Y; 13:28049691-28049691	skin	malignant_melanoma	Substitution - Missense
c.1508T>A; p.M503K; 13:28035584-28035584	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1792_1793ins48; p.Y597_E598ins16; 13:28034126-28034127	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>G; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1809_1810ins21; p.W603_E604insYEYDLKW; 13:28034109-28034110	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1758T>G; p.D586E; 13:28034161-28034161	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1773_1774ins57; p.L610_E611ins19; 13:28034145-28034146	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.1799_1800ins24; p.Y599_D600insEYEYEYEY; 13:28034119-28034120	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Deletion - In frame
c.1799_1800ins24; p.Y599_D600insEYEYEYEY; 13:28034119-28034120	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.143G>A; p.G48E; 13:28070513-28070513	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2944G>A; p.G982R; 13:28004090-28004090	genital_tract; extragonadal	germ_cell_tumour; mixed	Substitution - Missense
c.1799_1800ins24; p.Y599_D600insEYEYEYEY; 13:28034119-28034120	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.424C>A; p.L142I; 13:28057407-28057407	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1799_1800ins24; p.Y599_D600insEYEYEYEY; 13:28034119-28034120	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.2506_2508delATC; p.I836delI; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Deletion - In frame
c.876C>T; p.L292L; 13:28049641-28049641	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2005G>A; p.G669R; 13:28028226-28028226	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1794_1795ins42; p.E598_Y599ins14; 13:28034124-28034125	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Insertion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.1781_1799>13; p.F594_D600>SPPPH; 13:28034120-28034138	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Complex - deletion inframe
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.1797_1798ins24; p.Y599_D600insR*; 13:28034121-28034122	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2523C>A; p.N841K; 13:28018485-28018485	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2523C>A; p.N841K; 13:28018485-28018485	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1934_1935ins168; p.M645_L646ins56; 13:28033894-28033895	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2542G>C; p.A848P; 13:28015701-28015701	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_leukaemic_transformation_of_chronic_myelomonocytic_leukaemia	Substitution - Missense
c.1548A>G; p.A516A; 13:28035544-28035544	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1943-2A>T; p.?; 13:28028290-28028290	lung	carcinoma; adenocarcinoma	Unknown
c.2507_2509delTCA; p.I836delI; 13:28018499-28018501	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.1600C>T; p.P534S; 13:28034405-28034405	skin	malignant_melanoma	Substitution - Missense
c.2538C>T; p.G846G; 13:28018470-28018470	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2507_2509delTCA; p.I836delI; 13:28018499-28018501	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.2034_2035ins15; p.L678_G679insIVKLL; 13:28028196-28028197	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.582G>A; p.V194V; 13:28052577-28052577	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2504A>G; p.D835G; 13:28018504-28018504	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1111G>C; p.V371L; 13:28048369-28048369	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2507_2509delTCA; p.I836delI; 13:28018499-28018501	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.1458G>A; p.K486K; 13:28035634-28035634	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.523A>T; p.K175*; 13:28052636-28052636	skin	malignant_melanoma	Substitution - Nonsense
c.2298T>G; p.I766M; 13:28023470-28023470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1768_1773TTCTAC>GGGGAC; p.F590_Y591>GD; 13:28034146-28034151	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Complex - compound substitution
c.1779_1780ins48; p.D593_F594ins16; 13:28034139-28034140	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.489C>T; p.T163T; 13:28052670-28052670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1034T>C; p.V345A; 13:28049386-28049386	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2504A>C; p.D835A; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.85G>C; p.D29H; 13:28070571-28070571	skin	malignant_melanoma	Substitution - Missense
c.?_?ins?; p.602_603>20; 13:28034112-28034113	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Complex - insertion inframe
c.92C>T; p.P31L; 13:28070564-28070564	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1800_1801ins60; p.D600_L601ins20; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2891A>C; p.E964A; 13:28004143-28004143	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1775T>C; p.V592A; 13:28034144-28034144	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>C; p.D835A; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.92C>T; p.P31L; 13:28070564-28070564	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.273G>A; p.L91L; 13:28061962-28061962	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.391T>G; p.L131V; 13:28057440-28057440	skin	malignant_melanoma	Substitution - Missense
c.20A>G; p.D7G; 13:28100491-28100491	thyroid	other; neoplasm	Substitution - Missense
c.2504A>C; p.D835A; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2672G>A; p.G891D; 13:28015238-28015238	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.286G>A; p.D96N; 13:28061949-28061949	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1715A>G; p.Y572C; 13:28034204-28034204	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1715A>G; p.Y572C; 13:28034204-28034204	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDS	Substitution - Missense
c.1715A>G; p.Y572C; 13:28034204-28034204	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1802T>C; p.L601P; 13:28034117-28034117	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2845G>A; p.D949N; 13:28014466-28014466	skin	malignant_melanoma	Substitution - Missense
c.1805_1806ins33; p.L601_K602ins11; 13:28034113-28034114	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1615C>A; p.Q539K; 13:28034390-28034390	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.521G>A; p.R174K; 13:28052638-28052638	skin; trunk	malignant_melanoma	Substitution - Missense
c.1866_1867ins63; p.K623_V624ins21; 13:28033962-28033963	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2209A>G; p.M737V; 13:28024942-28024942	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1794_1795ins75; p.E598_Y599ins25; 13:28034124-28034125	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2928C>A; p.S976R; 13:28004106-28004106	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.932G>A; p.R311Q; 13:28049488-28049488	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2209A>G; p.M737V; 13:28024942-28024942	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.540C>T; p.D180D; 13:28052619-28052619	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2515G>C; p.D839H; 13:28018493-28018493	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1755_1756ins42; p.D600_L601ins14; 13:28034163-28034164	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1776T>C; p.V592V; 13:28034143-28034143	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2079C>T; p.Y693Y; 13:28027216-28027216	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2161C>A; p.H721N; 13:28027134-28027134	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1829_1830ins192; p.L610_E611ins64; 13:28034089-28034090	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1828_1829ins57; p.N609_L610ins19; 13:28034090-28034091	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1881A>G; p.A627A; 13:28033948-28033948	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2546G>A; p.R849H; 13:28015697-28015697	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.979T>C; p.Y327H; 13:28049441-28049441	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2456T>C; p.V819A; 13:28018552-28018552	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.1824_1825ins69; p.E608_N609ins23; 13:28034094-28034095	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2524T>C; p.Y842H; 13:28018484-28018484	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1771_1773delTAC; p.Y591delY; 13:28034146-28034148	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1987A>C; p.K663Q; 13:28028244-28028244	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.427C>A; p.L143I; 13:28057404-28057404	breast	carcinoma	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDS	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.?_?ins?; p.612_613>33; 13:28034082-28034083	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Complex - insertion inframe
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1769_1770ins24; p.Y597_E598insDYVDFREY; 13:28034149-28034150	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>T; p.D835Y; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1804_1805ins24; p.L601_K602insIREYEYDL; 13:28034114-28034115	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2507T>G; p.I836S; 13:28018501-28018501	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1859_1860ins105; p.A620_F621ins35; 13:28033969-28033970	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2316A>T; p.K772N; 13:28023452-28023452	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2316A>T; p.K772N; 13:28023452-28023452	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1727T>A; p.L576Q; 13:28034192-28034192	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1775T>G; p.V592G; 13:28034144-28034144	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2822C>T; p.S941L; 13:28014489-28014489	skin	malignant_melanoma	Substitution - Missense
c.2506_2508ATC>TTT; p.I836F; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2506_2508ATC>TTT; p.I836F; 13:28018500-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1096G>T; p.E366*; 13:28048384-28048384	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2039C>T; p.A680V; 13:28028192-28028192	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1775_1776ins21; p.D600_L601insFREYEYD; 13:28034143-28034144	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2039C>T; p.A680V; 13:28028192-28028192	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.541G>A; p.A181T; 13:28052618-28052618	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2039C>T; p.A680V; 13:28028192-28028192	thyroid	carcinoma; papillary_carcinoma	Substitution - Missense
c.2039C>T; p.A680V; 13:28028192-28028192	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; blastic_plasmacytoid_dendritic_cell_neoplasm	Substitution - Missense
c.121A>T; p.K41*; 13:28070535-28070535	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2521A>C; p.N841H; 13:28018487-28018487	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1518C>T; p.A506A; 13:28035574-28035574	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.856G>T; p.E286*; 13:28049661-28049661	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2291-2A>G; p.?; 13:28023479-28023479	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1823_1824ins75; p.E608_N609ins25; 13:28034095-28034096	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.869A>C; p.K290T; 13:28049648-28049648	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1523A>G; p.K508R; 13:28035569-28035569	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2073T>G; p.F691L; 13:28027222-28027222	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2073T>G; p.F691L; 13:28027222-28027222	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2073T>G; p.F691L; 13:28027222-28027222	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2222G>T; p.R741I; 13:28024929-28024929	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2502A>G; p.R834R; 13:28018506-28018506	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1805_1806ins54; p.L601_K602ins18; 13:28034113-28034114	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2440G>A; p.A814T; 13:28018568-28018568	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1811_1812ins39; p.W603_E604ins13; 13:28034107-28034108	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1765delT; p.Y589fs*22; 13:28034154-28034154	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - Frameshift
c.1795_1796ins21; p.E598_Y599insFDFREYE; 13:28034123-28034124	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2092G>T; p.D698Y; 13:28027203-28027203	ovary	other; neoplasm	Substitution - Missense
c.1800_1801ins42; p.D600_L601ins14; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1788_1789ins36; p.E596_Y597ins12; 13:28034130-28034131	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.239C>T; p.A80V; 13:28061996-28061996	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1817_1818ins24; p.P606_R607insYDLKWEFP; 13:28034101-28034102	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1788_1789ins36; p.E596_Y597ins12; 13:28034130-28034131	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1817_1818ins45; p.P606_R607ins15; 13:28034101-28034102	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Insertion - In frame
c.1817_1818ins36; p.P606_R607ins12; 13:28034101-28034102	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Insertion - In frame
c.1778_1779ins60; p.V592_D593ins20; 13:28034140-28034141	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Insertion - In frame
c.1739_1740ins66; p.Q580_V581ins*; 13:28034179-28034180	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1793_1794ins33; p.Y597_E598ins11; 13:28034125-28034126	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.1793_1794ins33; p.Y597_E598ins11; 13:28034125-28034126	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1878C>T; p.N626N; 13:28033951-28033951	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.166G>A; p.V56I; 13:28062069-28062069	skin	malignant_melanoma	Substitution - Missense
c.1800_1801ins84; p.D600_L601ins28; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1363G>A; p.D455N; 13:28035990-28035990	skin	malignant_melanoma	Substitution - Missense
c.743-8T>C; p.?; 13:28049782-28049782	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Unknown
c.1837+4_1837+5ins36; p.?; 13:28034077-28034078	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Unknown
c.1813_1814ins69; p.E604_F605ins23; 13:28034105-28034106	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1837+4_1837+5ins36; p.?; 13:28034077-28034078	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.590T>C; p.V197A; 13:28052569-28052569	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1799_1800ins78; p.Y599_D600ins26; 13:28034119-28034120	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1473G>T; p.V491V; 13:28035619-28035619	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.1218T>C; p.F406F; 13:28037276-28037276	central_nervous_system; brain	glioma	Substitution - coding silent
c.1909G>A; p.V637I; 13:28033920-28033920	skin	malignant_melanoma	Substitution - Missense
c.1788_1789ins33; p.E596_Y597ins11; 13:28034130-28034131	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1854A>G; p.S618S; 13:28033975-28033975	skin	malignant_melanoma	Substitution - coding silent
c.1842G>T; p.K614N; 13:28033987-28033987	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1842G>T; p.K614N; 13:28033987-28033987	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1807_1808ins18; p.K602_W603insYEYDLK; 13:28034111-28034112	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2662C>T; p.P888S; 13:28015248-28015248	skin	malignant_melanoma	Substitution - Missense
c.312C>T; p.L104L; 13:28061923-28061923	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1790_1791ins27; p.F605_P606insGEYDLKWEF; 13:28034128-28034129	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.110T>C; p.L37S; 13:28070546-28070546	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1826_1827ins57; p.E608_N609ins19; 13:28034092-28034093	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1817_1818ins30; p.P606_R607ins10; 13:28034101-28034102	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1853_1854ins63; p.S618_G619ins21; 13:28033975-28033976	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1828_1829ins30; p.N609_L610ins10; 13:28034090-28034091	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2503_2504GA>TT; p.D835F; 13:28018504-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503_2504GA>TT; p.D835F; 13:28018504-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503_2504GA>TT; p.D835F; 13:28018504-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1078G>A; p.E360K; 13:28048402-28048402	skin	malignant_melanoma	Substitution - Missense
c.1837_1837+1ins45; p.F612_G613ins15; 13:28034081-28034082	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2503_2504GA>TT; p.D835F; 13:28018504-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1782_1783ins30; p.F594_R595ins10; 13:28034136-28034137	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1782_1783ins30; p.F594_R595ins10; 13:28034136-28034137	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1798_1799ins45; p.Y599_D600ins15; 13:28034120-28034121	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1782_1783ins30; p.F594_R595ins10; 13:28034136-28034137	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_related	Insertion - In frame
c.1730A>C; p.Q577P; 13:28034189-28034189	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1782_1783ins30; p.F594_R595ins10; 13:28034136-28034137	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1798_1799ins45; p.Y599_D600ins15; 13:28034120-28034121	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDS	Insertion - In frame
c.2503_2505delGAT; p.D835delD; 13:28018503-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.218_219GG>AA; p.G73E; 13:28062016-28062017	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2882G>C; p.R961P; 13:28004152-28004152	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2198C>A; p.P733Q; 13:28027097-28027097	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1988A>G; p.K663R; 13:28028243-28028243	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1803_1804ins72; p.L601_K602ins24; 13:28034115-28034116	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1780T>A; p.F594I; 13:28034139-28034139	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2340G>A; p.L780L; 13:28023428-28023428	skin	malignant_melanoma	Substitution - coding silent
c.1780T>A; p.F594I; 13:28034139-28034139	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1311G>A; p.R437R; 13:28036042-28036042	skin	malignant_melanoma	Substitution - coding silent
c.1481A>T; p.Q494L; 13:28035611-28035611	liver	carcinoma	Substitution - Missense
c.1398G>A; p.K466K; 13:28035955-28035955	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1306A>G; p.R436G; 13:28037188-28037188	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.559G>C; p.E187Q; 13:28052600-28052600	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1311G>A; p.R437R; 13:28036042-28036042	skin	malignant_melanoma	Substitution - coding silent
c.1481A>T; p.Q494L; 13:28035611-28035611	liver	carcinoma	Substitution - Missense
c.1545T>C; p.C515C; 13:28035547-28035547	central_nervous_system; brain	glioma	Substitution - coding silent
c.1815_1816ins18; p.F605_P606insDLKWEF; 13:28034103-28034104	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2248G>T; p.D750Y; 13:28024903-28024903	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1804_1805ins21; p.L601_K602insREYEYDL; 13:28034114-28034115	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1986C>T; p.L662L; 13:28028245-28028245	breast	carcinoma	Substitution - coding silent
c.1770_1771ins33; p.F590_Y591insFQRI*; 13:28034148-28034149	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2002C>T; p.L668L; 13:28028229-28028229	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1834_1835ins69; p.E611_F612ins23; 13:28034084-28034085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.598G>C; p.D200H; 13:28052561-28052561	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.499A>G; p.T167A; 13:28052660-28052660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1705-1G>T; p.?; 13:28034215-28034215	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.499A>G; p.T167A; 13:28052660-28052660	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.499A>G; p.T167A; 13:28052660-28052660	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.499A>G; p.T167A; 13:28052660-28052660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.499A>G; p.T167A; 13:28052660-28052660	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.871G>C; p.A291P; 13:28049646-28049646	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.702A>G; p.R234R; 13:28050135-28050135	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1471G>C; p.V491L; 13:28035621-28035621	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1471G>C; p.V491L; 13:28035621-28035621	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2623G>A; p.G875R; 13:28015620-28015620	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1770_1782>A; p.F590_F594>L; 13:28034137-28034149	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Complex - deletion inframe
c.1833_1834ins75; p.E611_F612ins25; 13:28034085-28034086	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2003T>C; p.L668P; 13:28028228-28028228	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1833_1834ins75; p.E611_F612ins25; 13:28034085-28034086	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2522A>G; p.N841S; 13:28018486-28018486	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2504_2506delATA; p.D835_I836>V; 13:28018502-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Complex - deletion inframe
c.1791_1792ins54; p.Y597_E598ins18; 13:28034127-28034128	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2137A>G; p.T713A; 13:28027158-28027158	skin	malignant_melanoma	Substitution - Missense
c.1775_1776insTGG; p.V592_D593insG; 13:28034143-28034144	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1732_1734ATG>18; p.M578>NLRNPP; 13:28034185-28034187	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Complex - insertion inframe
c.1766delA; p.Y589fs*22; 13:28034153-28034153	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - Frameshift
c.1351T>C; p.S451P; 13:28036002-28036002	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.9G>A; p.A3A; 13:28100502-28100502	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - coding silent
c.2508_2510delCAT; p.I836delI; 13:28018498-28018500	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2508_2510delCAT; p.I836delI; 13:28018498-28018500	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.2508_2510delCAT; p.I836delI; 13:28018498-28018500	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.1814_1815ins69; p.F605_P606ins23; 13:28034104-28034105	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1683A>G; p.L561L; 13:28034322-28034322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1683A>G; p.L561L; 13:28034322-28034322	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - coding silent
c.1192G>A; p.D398N; 13:28048288-28048288	skin	malignant_melanoma	Substitution - Missense
c.331T>G; p.S111A; 13:28061904-28061904	skin	malignant_melanoma	Substitution - Missense
c.1683A>G; p.L561L; 13:28034322-28034322	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1683A>G; p.L561L; 13:28034322-28034322	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1683A>G; p.L561L; 13:28034322-28034322	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1683A>G; p.L561L; 13:28034322-28034322	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1683A>G; p.L561L; 13:28034322-28034322	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2638G>A; p.E880K; 13:28015605-28015605	skin	malignant_melanoma	Substitution - Missense
c.1683A>G; p.L561L; 13:28034322-28034322	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - coding silent
c.1789T>A; p.Y597N; 13:28034130-28034130	skin	malignant_melanoma	Substitution - Missense
c.1683A>G; p.L561L; 13:28034322-28034322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2638G>A; p.E880K; 13:28015605-28015605	skin	malignant_melanoma	Substitution - Missense
c.1989G>C; p.K663N; 13:28028242-28028242	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1556C>A; p.S519Y; 13:28035536-28035536	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1285A>G; p.K429E; 13:28037209-28037209	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2146G>C; p.E716Q; 13:28027149-28027149	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1639A>G; p.T547A; 13:28034366-28034366	skin; neck	malignant_melanoma	Substitution - Missense
c.2753+2T>G; p.?; 13:28015155-28015155	ovary	carcinoma; serous_carcinoma	Unknown
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1115G>C; p.R372T; 13:28048365-28048365	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1774G>A; p.V592I; 13:28034145-28034145	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDS	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1803_1804ins81; p.L601_K602ins27; 13:28034115-28034116	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1803_1804ins81; p.L601_K602ins27; 13:28034115-28034116	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1803_1804ins81; p.L601_K602ins27; 13:28034115-28034116	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.212_213GC>TA; p.S71I; 13:28062022-28062023	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1803_1804ins81; p.L601_K602ins27; 13:28034115-28034116	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1770C>G; p.F590L; 13:28034149-28034149	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2504A>T; p.D835V; 13:28018504-28018504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1803_1804ins63; p.L601_K602ins21; 13:28034115-28034116	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2509_2510AT>CC; p.M837P; 13:28018498-28018499	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2509_2510AT>CC; p.M837P; 13:28018498-28018499	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1831_1832ins60; p.L610_E611ins20; 13:28034087-28034088	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1850G>A; p.G617E; 13:28033979-28033979	skin	malignant_melanoma	Substitution - Missense
c.2956C>T; p.P986S; 13:28004078-28004078	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1850G>A; p.G617E; 13:28033979-28033979	skin	malignant_melanoma	Substitution - Missense
c.2509A>C; p.M837L; 13:28018499-28018499	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2418G>A; p.S806S; 13:28023350-28023350	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2501G>A; p.R834Q; 13:28018507-28018507	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2501G>A; p.R834Q; 13:28018507-28018507	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1796_1797ins21; p.Y599>*; 13:28034122-28034123	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1801_1802ins30; p.D600_L601ins10; 13:28034117-28034118	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2501G>A; p.R834Q; 13:28018507-28018507	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1352C>T; p.S451F; 13:28036001-28036001	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.659T>G; p.V220G; 13:28050178-28050178	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1801_1802ins42; p.D600_L601ins14; 13:28034117-28034118	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1352C>T; p.S451F; 13:28036001-28036001	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1310G>A; p.R437K; 13:28036043-28036043	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1352C>T; p.S451F; 13:28036001-28036001	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2858C>T; p.A953V; 13:28014453-28014453	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1825_1826ins66; p.E608_N609insI*; 13:28034093-28034094	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Insertion - In frame
c.1361C>T; p.S454L; 13:28035992-28035992	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.659T>G; p.V220G; 13:28050178-28050178	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2506_2507AT>TTGGA; p.I836>LD; 13:28018501-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Complex - insertion inframe
c.1310G>A; p.R437K; 13:28036043-28036043	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.2858C>T; p.A953V; 13:28014453-28014453	ovary	other; neoplasm	Substitution - Missense
c.1361C>T; p.S454L; 13:28035992-28035992	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1716_1717ins96; p.Y599_D600ins32; 13:28034202-28034203	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1155C>T; p.F385F; 13:28048325-28048325	liver	carcinoma	Substitution - coding silent
c.1811_1812ins30; p.W603_E604ins10; 13:28034107-28034108	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2007A>T; p.G669G; 13:28028224-28028224	skin	malignant_melanoma	Substitution - coding silent
c.1811_1812ins30; p.W603_E604ins10; 13:28034107-28034108	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1155C>T; p.F385F; 13:28048325-28048325	liver	carcinoma	Substitution - coding silent
c.2492G>A; p.G831E; 13:28018516-28018516	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.2492G>A; p.G831E; 13:28018516-28018516	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2492G>A; p.G831E; 13:28018516-28018516	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.877G>A; p.E293K; 13:28049640-28049640	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1812_1813ins30; p.E604_F605ins10; 13:28034106-28034107	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2799G>A; p.R933R; 13:28014512-28014512	breast	carcinoma	Substitution - coding silent
c.196G>A; p.A66T; 13:28062039-28062039	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.196G>A; p.A66T; 13:28062039-28062039	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2306A>G; p.E769G; 13:28023462-28023462	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2040G>A; p.A680A; 13:28028191-28028191	pancreas	carcinoma	Substitution - coding silent
c.1770_1771ins18; p.F590_Y591ins*; 13:28034148-28034149	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.93T>C; p.P31P; 13:28070563-28070563	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1836_1837ins75; p.F612_G613ins25; 13:28034082-28034083	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2146G>A; p.E716K; 13:28027149-28027149	skin	malignant_melanoma	Substitution - Missense
c.2503G>A; p.D835N; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1098G>T; p.E366D; 13:28048382-28048382	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2500_2505delCGAGAT; p.R834_D835delRD; 13:28018503-28018508	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.2340G>C; p.L780F; 13:28023428-28023428	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2503G>A; p.D835N; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1215G>A; p.K405K; 13:28037279-28037279	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2503G>A; p.D835N; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>A; p.D835N; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>A; p.D835N; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>A; p.D835N; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.970G>A; p.D324N; 13:28049450-28049450	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.970G>A; p.D324N; 13:28049450-28049450	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2565G>T; p.M855I; 13:28015678-28015678	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1830_1831ins75; p.L610_E611ins25; 13:28034088-28034089	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2444G>A; p.R815K; 13:28018564-28018564	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1073A>T; p.D358V; 13:28048407-28048407	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2955_2956delTC; p.P986fs*>8; 13:28004078-28004079	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2955_2956delTC; p.P986fs*>8; 13:28004078-28004079	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.?_?ins?; p.E604_F605ins15; 13:28034106-28034107	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2008_2009insA; p.S670fs*23; 13:28028222-28028223	liver	carcinoma	Insertion - Frameshift
c.2955_2956delTC; p.P986fs*>8; 13:28004078-28004079	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2955_2956delTC; p.P986fs*>8; 13:28004078-28004079	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2840T>C; p.L947P; 13:28014471-28014471	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2955_2956delTC; p.P986fs*>8; 13:28004078-28004079	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1811_1812ins42; p.W603_E604ins14; 13:28034107-28034108	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Insertion - In frame
c.915A>G; p.T305T; 13:28049505-28049505	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1769_1770ins63; p.L610_E611ins21; 13:28034149-28034150	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2857G>A; p.A953T; 13:28014454-28014454	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1243G>T; p.E415*; 13:28037251-28037251	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.276_277insA; p.V93fs*16; 13:28061958-28061959	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.1801_1802ins72; p.D600_L601ins24; 13:28034117-28034118	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1367G>A; p.G456E; 13:28035986-28035986	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1838_1839ins69; p.G613_K614ins23; 13:28033990-28033991	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1830_1831ins51; p.L610_E611ins17; 13:28034088-28034089	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2362C>A; p.L788I; 13:28023406-28023406	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1793_1794ins63; p.E598_Y599ins21; 13:28034125-28034126	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1243G>A; p.E415K; 13:28037251-28037251	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1243G>A; p.E415K; 13:28037251-28037251	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2034_2035ins15; p.L678_G679insIVNLL; 13:28028196-28028197	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1794_1795ins?; p.E598_Y599insFYVDFREYE; 13:28034124-28034125	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1798_1799ins27; p.D600_L601insVDFREYEYD; 13:28034120-28034121	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2208-2A>G; p.?; 13:28024945-28024945	lung	carcinoma; adenocarcinoma	Unknown
c.2714G>T; p.G905V; 13:28015196-28015196	skin	malignant_melanoma	Substitution - Missense
c.1160G>A; p.R387Q; 13:28048320-28048320	skin	malignant_melanoma	Substitution - Missense
c.149C>T; p.S50L; 13:28070507-28070507	skin	malignant_melanoma	Substitution - Missense
c.1160G>A; p.R387Q; 13:28048320-28048320	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1844T>C; p.V615A; 13:28033985-28033985	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1160G>A; p.R387Q; 13:28048320-28048320	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1763A>T; p.E588V; 13:28034156-28034156	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1788_1789ins36; p.E596_Y597ins12; 13:28034130-28034131	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1797_1798ins57; p.Y599_D600ins19; 13:28034121-28034122	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2172T>A; p.S724R; 13:28027123-28027123	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1797_1798ins57; p.Y599_D600ins19; 13:28034121-28034122	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1797_1798ins57; p.Y599_D600ins19; 13:28034121-28034122	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2516A>G; p.D839G; 13:28018492-28018492	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2516A>G; p.D839G; 13:28018492-28018492	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; granulocytic_sarcoma	Substitution - Missense
c.1721_1722insCCGGGAGCC; p.S574_Q575insREP; 13:28034197-28034198	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Insertion - In frame
c.2516A>G; p.D839G; 13:28018492-28018492	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2516A>G; p.D839G; 13:28018492-28018492	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2516A>G; p.D839G; 13:28018492-28018492	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1964G>A; p.R655K; 13:28028267-28028267	skin; mucosal	malignant_melanoma	Substitution - Missense
c.2282A>C; p.H761P; 13:28024869-28024869	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2211G>C; p.M737I; 13:28024940-28024940	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.2038delG; p.A680fs*10; 13:28028193-28028193	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2211G>C; p.M737I; 13:28024940-28024940	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1776_1777ins36; p.D600_L601ins12; 13:28034142-28034143	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.711G>T; p.L237L; 13:28050126-28050126	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2010C>G; p.S670R; 13:28028221-28028221	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2367T>C; p.L789L; 13:28023401-28023401	skin	malignant_melanoma	Substitution - coding silent
c.1799_1800ins36; p.Y599_D600ins12; 13:28034119-28034120	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1171C>T; p.P391S; 13:28048309-28048309	skin	malignant_melanoma	Substitution - Missense
c.2505T>A; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2505T>A; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.190G>A; p.G64R; 13:28062045-28062045	pancreas	carcinoma	Substitution - Missense
c.1782_1783ins36; p.F594_R595ins12; 13:28034136-28034137	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2508C>G; p.I836M; 13:28018500-28018500	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; juvenile_myelomonocytic_leukaemia	Substitution - Missense
c.418G>T; p.E140*; 13:28057413-28057413	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2505T>A; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2508C>G; p.I836M; 13:28018500-28018500	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1800_1801ins21; p.D600_L601insFREYEYD; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_leukaemia_of_ambiguous_lineage_associated_with_MDS	Insertion - In frame
c.2505T>A; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2508C>G; p.I836M; 13:28018500-28018500	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2508C>G; p.I836M; 13:28018500-28018500	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2505T>A; p.D835E; 13:28018503-28018503	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2508C>G; p.I836M; 13:28018500-28018500	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1370A>G; p.Y457C; 13:28035983-28035983	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1785_1786ins39; p.R595_E596ins13; 13:28034133-28034134	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.631C>T; p.P211S; 13:28050206-28050206	skin	malignant_melanoma	Substitution - Missense
c.2753+2T>C; p.?; 13:28015155-28015155	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.2957C>A; p.P986Q; 13:28004077-28004077	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1724A>C; p.Q575P; 13:28034195-28034195	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDS	Substitution - Missense
c.366C>G; p.N122K; 13:28061869-28061869	skin	malignant_melanoma	Substitution - Missense
c.1681C>A; p.L561I; 13:28034324-28034324	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.928A>G; p.I310V; 13:28049492-28049492	liver	carcinoma	Substitution - Missense
c.1838G>A; p.G613E; 13:28033991-28033991	skin	malignant_melanoma	Substitution - Missense
c.1159C>T; p.R387*; 13:28048321-28048321	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2668C>T; p.P890S; 13:28015242-28015242	prostate	carcinoma	Substitution - Missense
c.1362G>T; p.S454S; 13:28035991-28035991	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1879_1880ins93; p.N626_A627ins31; 13:28033949-28033950	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2159A>T; p.E720V; 13:28027136-28027136	skin	malignant_melanoma	Substitution - Missense
c.1414C>T; p.P472S; 13:28035939-28035939	liver	carcinoma	Substitution - Missense
c.1414C>T; p.P472S; 13:28035939-28035939	liver	carcinoma	Substitution - Missense
c.2817G>T; p.L939F; 13:28014494-28014494	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2528T>C; p.V843A; 13:28018480-28018480	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2793G>A; p.R931R; 13:28014518-28014518	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1827_1828ins57; p.N609_L610ins19; 13:28034091-28034092	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2793G>A; p.R931R; 13:28014518-28014518	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1414C>T; p.P472S; 13:28035939-28035939	liver	carcinoma	Substitution - Missense
c.1581C>T; p.I527I; 13:28035511-28035511	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1517C>T; p.A506V; 13:28035575-28035575	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.686T>A; p.I229K; 13:28050151-28050151	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myelomonocytic_leukaemia	Substitution - Missense
c.1581C>T; p.I527I; 13:28035511-28035511	skin	malignant_melanoma	Substitution - coding silent
c.2491G>A; p.G831R; 13:28018517-28018517	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2669C>T; p.P890L; 13:28015241-28015241	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.1792_1793ins24; p.E598>DMISPEDMK; 13:28034126-28034127	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Complex - insertion inframe
c.1881A>T; p.A627A; 13:28033948-28033948	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2623_2624GG>AA; p.G875K; 13:28015619-28015620	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1936C>T; p.L646L; 13:28033893-28033893	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2029C>T; p.L677L; 13:28028202-28028202	NS	NS	Substitution - coding silent
c.1777_1779delGAT; p.D593delD; 13:28034140-28034142	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Deletion - In frame
c.423C>A; p.Y141*; 13:28057408-28057408	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Nonsense
c.198G>A; p.A66A; 13:28062037-28062037	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1310-3T>C; p.?; 13:28036046-28036046	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.198G>A; p.A66A; 13:28062037-28062037	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.346C>T; p.P116S; 13:28061889-28061889	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1741_1742ins57; p.E598_Y599ins19; 13:28034177-28034178	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2678C>T; p.P893L; 13:28015232-28015232	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.?_?ins?; p.G613_K614ins33; 13:28033989-28033990	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1785A>G; p.R595R; 13:28034134-28034134	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2506A>C; p.I836L; 13:28018502-28018502	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.285C>T; p.V95V; 13:28061950-28061950	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2838G>T; p.Q946H; 13:28014473-28014473	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.380C>T; p.S127F; 13:28057451-28057451	skin	malignant_melanoma	Substitution - Missense
c.?_?ins?; p.F612_G613ins20; 13:28034082-28034083	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1552A>G; p.N518D; 13:28035540-28035540	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1815_1816ins66; p.F605_P606ins22; 13:28034103-28034104	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1836_1837ins48; p.F612_G613ins16; 13:28034082-28034083	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.622G>C; p.E208Q; 13:28050215-28050215	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2498C>A; p.A833D; 13:28018510-28018510	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.580G>A; p.V194M; 13:28052579-28052579	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1217T>G; p.F406C; 13:28037277-28037277	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.580G>A; p.V194M; 13:28052579-28052579	stomach	carcinoma	Substitution - Missense
c.580G>A; p.V194M; 13:28052579-28052579	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1202A>G; p.Y401C; 13:28048278-28048278	breast	carcinoma	Substitution - Missense
c.1736T>C; p.V579A; 13:28034183-28034183	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2683G>T; p.D895Y; 13:28015227-28015227	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1787_1788ins30; p.R595_E596ins10; 13:28034131-28034132	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1807_1808ins18; p.K602_W603insYEYDLK; 13:28034111-28034112	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.?_?ins?; p.F594_R595ins12; 13:28034136-28034137	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1762G>A; p.E588K; 13:28034157-28034157	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1807_1808ins18; p.K602_W603insYEYDLK; 13:28034111-28034112	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myelomonocytic_leukaemia	Insertion - In frame
c.393G>A; p.L131L; 13:28057438-28057438	skin	malignant_melanoma	Substitution - coding silent
c.526A>G; p.M176V; 13:28052633-28052633	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2440G>T; p.A814S; 13:28018568-28018568	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1787_1788ins21; p.R595_E596insDFYVDFR; 13:28034131-28034132	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myelomonocytic_leukaemia	Insertion - In frame
c.1090T>C; p.Y364H; 13:28048390-28048390	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2890G>A; p.E964K; 13:28004144-28004144	skin; arm	malignant_melanoma	Substitution - Missense
c.2683G>A; p.D895N; 13:28015227-28015227	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.197C>A; p.A66E; 13:28062038-28062038	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1795_1796ins51; p.E598_Y599ins17; 13:28034123-28034124	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1796A>T; p.Y599F; 13:28034123-28034123	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.393G>C; p.L131F; 13:28057438-28057438	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1875G>A; p.M625I; 13:28033954-28033954	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1796A>T; p.Y599F; 13:28034123-28034123	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1853C>T; p.S618L; 13:28033976-28033976	skin	malignant_melanoma	Substitution - Missense
c.1744_1745ins54; p.T582>19; 13:28034174-28034175	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1853C>T; p.S618L; 13:28033976-28033976	skin	malignant_melanoma	Substitution - Missense
c.206_207CC>TT; p.P69L; 13:28062028-28062029	skin	malignant_melanoma	Substitution - Missense
c.699delC; p.R234fs*14; 13:28050138-28050138	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1007C>G; p.P336R; 13:28049413-28049413	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2950_2951delCT; p.P986fs*>8; 13:28004083-28004084	large_intestine; colon	carcinoma	Deletion - Frameshift
c.649G>A; p.E217K; 13:28050188-28050188	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1171_1172CC>TT; p.P391F; 13:28048308-28048309	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1809_1810ins30; p.W603_E604ins10; 13:28034109-28034110	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1816_1817ins63; p.P606_R607ins21; 13:28034102-28034103	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myelomonocytic_leukaemia	Insertion - In frame
c.1819_1820ins39; p.P606_R607ins13; 13:28034099-28034100	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.882G>A; p.E294E; 13:28049635-28049635	skin	malignant_melanoma	Substitution - coding silent
c.1793_1794ins24; p.Y597_E598insDYVDFREY; 13:28034125-28034126	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1829_1830ins96; p.L610_E611ins32; 13:28034089-28034090	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2001G>A; p.Q667Q; 13:28028230-28028230	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2503G>C; p.D835H; 13:28018505-28018505	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1134A>C; p.Q378H; 13:28048346-28048346	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.2441C>T; p.A814V; 13:28018567-28018567	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.966A>G; p.R322R; 13:28049454-28049454	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.88C>T; p.L30L; 13:28070568-28070568	breast	carcinoma	Substitution - coding silent
c.2459C>A; p.T820N; 13:28018549-28018549	genital_tract; extragonadal	germ_cell_tumour; yolk_sac_tumour	Substitution - Missense
c.1780_1781ins33; p.D593_F594ins11; 13:28034138-28034139	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.884G>A; p.G295D; 13:28049536-28049536	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.526A>T; p.M176L; 13:28052633-28052633	skin	malignant_melanoma	Substitution - Missense
c.1073A>C; p.D358A; 13:28048407-28048407	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1769_1770ins39; p.F590_Y591ins13; 13:28034149-28034150	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1812_1813ins66; p.E604_F605ins22; 13:28034106-28034107	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.884G>A; p.G295D; 13:28049536-28049536	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2957C>T; p.P986L; 13:28004077-28004077	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1837+4_1837+5ins87; p.?; 13:28034077-28034078	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.2957C>T; p.P986L; 13:28004077-28004077	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2500C>T; p.R834*; 13:28018508-28018508	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1911C>A; p.V637V; 13:28033918-28033918	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2500C>T; p.R834*; 13:28018508-28018508	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1836T>A; p.F612L; 13:28034083-28034083	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2685T>C; p.D895D; 13:28015225-28015225	pancreas	carcinoma	Substitution - coding silent
c.1815_1816ins39; p.F605_P606ins13; 13:28034103-28034104	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2464G>A; p.G822R; 13:28018544-28018544	skin	malignant_melanoma	Substitution - Missense
c.1240G>T; p.G414*; 13:28037254-28037254	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1836_1837ins51; p.F612_G613ins17; 13:28034082-28034083	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Insertion - In frame
c.1800_1801ins51; p.D600_L601ins17; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1821_1822ins69; p.R607_E608ins23; 13:28034097-28034098	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Insertion - In frame
c.305C>T; p.S102F; 13:28061930-28061930	skin; neck	malignant_melanoma	Substitution - Missense
c.1426G>C; p.E476Q; 13:28035666-28035666	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1803_1804ins21; p.L601_K602insREYEYDL; 13:28034115-28034116	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1765_1776del12; p.Y589_V592delYFYV; 13:28034143-28034154	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Deletion - In frame
c.1800_1801ins51; p.D600_L601ins17; 13:28034118-28034119	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1830_1831ins54; p.L610_E611ins18; 13:28034088-28034089	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1776_1777ins60; p.V592_D593ins20; 13:28034142-28034143	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.2445G>T; p.R815S; 13:28018563-28018563	liver	carcinoma	Substitution - Missense
c.1801_1802ins21; p.L601_K602insQRI*; 13:28034117-28034118	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame
c.1842G>A; p.K614K; 13:28033987-28033987	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1842G>A; p.K614K; 13:28033987-28033987	oesophagus	carcinoma	Substitution - coding silent
c.1705_1740del36; p.Q569_Q580del12; 13:28034179-28034214	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Deletion - In frame
c.238G>A; p.A80T; 13:28061997-28061997	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2668C>A; p.P890T; 13:28015242-28015242	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.501A>G; p.T167T; 13:28052658-28052658	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2634G>A; p.L878L; 13:28015609-28015609	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1717_1718ins72; p.E573_S574ins14; 13:28034201-28034202	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - In frame

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]