| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 50514 |
Name | DEC1 |
Synonymous | deleted in esophageal cancer 1;DEC1;deleted in esophageal cancer 1 |
Definition | candidate tumor suppressor CTS9 |
Position | 9q32 |
Gene Type | protein-coding |
Mutation summary: | Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72 |
Mutation summary in protein domains | Top |
 |
The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers | Top |
 |
 |
Loss of Function mutations compare to missense mutations | Top |
 |
The copy number variations for various cancers | Top |
 |
The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
COSMIC somatic mutation [Top] | |||
|
Mutation (CDS; AA; Chr) |
Site |
Histology |
Mutation Type |
|---|---|---|---|
c.32G>A; p.W11*; 9:115400377-115400377 |
skin | malignant_melanoma | Substitution - Nonsense |
c.79C>T; p.H27Y; 9:115400424-115400424 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; mantle_cell_lymphoma | Substitution - Missense |
c.194C>A; p.A65E; 9:115401299-115401299 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.109A>G; p.R37G; 9:115401214-115401214 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.212G>C; p.*71S; 9:115402124-115402124 |
breast | carcinoma | Nonstop extension |
c.183G>A; p.R61R; 9:115401288-115401288 |
skin | malignant_melanoma | Substitution - coding silent |
c.67C>G; p.L23V; 9:115400412-115400412 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.63C>A; p.G21G; 9:115400408-115400408 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.195A>G; p.A65A; 9:115401300-115401300 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.46C>A; p.P16T; 9:115400391-115400391 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.84G>A; p.M28I; 9:115400429-115400429 |
skin | malignant_melanoma | Substitution - Missense |
c.182_183GG>AT; p.R61>?; 9:115401287-115401288 |
lung | carcinoma; adenocarcinoma | Complex |
c.212G>A; p.*71*; 9:115402124-115402124 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |