Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

51339

Name

DACT1

Synonymous

dishevelled-binding antagonist of beta-catenin 1;DACT1;dishevelled-binding antagonist of beta-catenin 1

Definition

dapper antagonist of catenin 1|dapper homolog 1|dapper, antagonist of beta-catenin, homolog 1|hepatocellular carcinoma novel gene 3 protein|heptacellular carcinoma novel gene 3

Position

14q23.1

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Top

The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

Top

Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.11.

The copy number variations for various cancers

Top

The copy number variations in 17 major cancer groups: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.253C>T; p.R85C; 14:58638455-58638455

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2470C>T; p.R824C; 14:58647093-58647093

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.688G>T; p.G230W; 14:58645311-58645311

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2171C>T; p.S724F; 14:58646794-58646794

 skinmalignant_melanomaSubstitution - Missense

c.1534delA; p.N513fs*67; 14:58646157-58646157

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.268C>T; p.L90L; 14:58638470-58638470

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.268C>T; p.L90L; 14:58638470-58638470

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.268C>T; p.L90L; 14:58638470-58638470

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1648G>A; p.E550K; 14:58646271-58646271

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1505T>C; p.V502A; 14:58646128-58646128

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1359delA; p.T455fs*52; 14:58645982-58645982

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.2262C>T; p.F754F; 14:58646885-58646885

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1704G>T; p.R568S; 14:58646327-58646327

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2262C>T; p.F754F; 14:58646885-58646885

 skinmalignant_melanomaSubstitution - coding silent

c.1042delA; p.T350fs*4; 14:58645665-58645665

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1732G>A; p.V578I; 14:58646355-58646355

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1732G>A; p.V578I; 14:58646355-58646355

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1732G>A; p.V578I; 14:58646355-58646355

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1371G>A; p.K457K; 14:58645994-58645994

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2120C>T; p.A707V; 14:58646743-58646743

 livercarcinomaSubstitution - Missense

c.1656G>A; p.A552A; 14:58646279-58646279

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2120C>T; p.A707V; 14:58646743-58646743

 livercarcinomaSubstitution - Missense

c.1025T>A; p.I342N; 14:58645648-58645648

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1154C>T; p.S385L; 14:58645777-58645777

 breastcarcinomaSubstitution - Missense

c.1445C>T; p.S482L; 14:58646068-58646068

 skinmalignant_melanomaSubstitution - Missense

c.2286C>T; p.S762S; 14:58646909-58646909

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1154C>T; p.S385L; 14:58645777-58645777

 livercarcinomaSubstitution - Missense

c.2286C>T; p.S762S; 14:58646909-58646909

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1154C>T; p.S385L; 14:58645777-58645777

 livercarcinomaSubstitution - Missense

c.1541G>T; p.S514I; 14:58646164-58646164

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.1158G>T; p.Q386H; 14:58645781-58645781

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1760G>A; p.R587H; 14:58646383-58646383

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1143G>T; p.P381P; 14:58645766-58645766

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1737G>A; p.V579V; 14:58646360-58646360

 skinmalignant_melanomaSubstitution - coding silent

c.847T>C; p.F283L; 14:58645470-58645470

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1982G>A; p.G661E; 14:58646605-58646605

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2032_2033insG; p.W679fs*44; 14:58646655-58646656

 skinmalignant_melanomaInsertion - Frameshift

c.1551C>T; p.G517G; 14:58646174-58646174

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.709T>C; p.S237P; 14:58645332-58645332

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.1906G>T; p.G636C; 14:58646529-58646529

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1551C>T; p.G517G; 14:58646174-58646174

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1472G>T; p.S491I; 14:58646095-58646095

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1551C>T; p.G517G; 14:58646174-58646174

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2390C>T; p.T797M; 14:58647013-58647013

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1264G>T; p.E422*; 14:58645887-58645887

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.938C>A; p.A313D; 14:58645561-58645561

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2384C>T; p.T795M; 14:58647007-58647007

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2384C>T; p.T795M; 14:58647007-58647007

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.2385G>A; p.T795T; 14:58647008-58647008

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.2384C>T; p.T795M; 14:58647007-58647007

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1571C>T; p.P524L; 14:58646194-58646194

 skinmalignant_melanomaSubstitution - Missense

c.1179G>T; p.K393N; 14:58645802-58645802

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1213A>T; p.I405L; 14:58645836-58645836

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.738C>A; p.V246V; 14:58645361-58645361

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2245T>C; p.Y749H; 14:58646868-58646868

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1146C>T; p.G382G; 14:58645769-58645769

 prostatecarcinomaSubstitution - coding silent

c.1938C>T; p.P646P; 14:58646561-58646561

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1469C>T; p.P490L; 14:58646092-58646092

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.803G>A; p.R268H; 14:58645426-58645426

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.803G>A; p.R268H; 14:58645426-58645426

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.803G>A; p.R268H; 14:58645426-58645426

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1269A>G; p.S423S; 14:58645892-58645892

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.721T>G; p.F241V; 14:58645344-58645344

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2304G>A; p.G768G; 14:58646927-58646927

 skinmalignant_melanomaSubstitution - coding silent

c.721T>C; p.F241L; 14:58645344-58645344

 skinmalignant_melanomaSubstitution - Missense

c.758A>C; p.K253T; 14:58645381-58645381

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1985G>A; p.R662Q; 14:58646608-58646608

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.165G>A; p.L55L; 14:58638367-58638367

 pancreascarcinomaSubstitution - coding silent

c.1143G>A; p.P381P; 14:58645766-58645766

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.346-1G>T; p.?; 14:58640735-58640735

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.1143G>A; p.P381P; 14:58645766-58645766

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1570C>T; p.P524S; 14:58646193-58646193

 skinmalignant_melanomaSubstitution - Missense

c.916T>C; p.C306R; 14:58645539-58645539

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.500G>T; p.G167V; 14:58641613-58641613

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.926C>T; p.S309F; 14:58645549-58645549

 skinmalignant_melanomaSubstitution - Missense

c.816A>G; p.P272P; 14:58645439-58645439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1554delC; p.P520fs*60; 14:58646177-58646177

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1554delC; p.P520fs*60; 14:58646177-58646177

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1554delC; p.P520fs*60; 14:58646177-58646177

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1554delC; p.P520fs*60; 14:58646177-58646177

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1554delC; p.P520fs*60; 14:58646177-58646177

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1554delC; p.P520fs*60; 14:58646177-58646177

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.917G>T; p.C306F; 14:58645540-58645540

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1554delC; p.P520fs*60; 14:58646177-58646177

 oesophagus; lower_thirdcarcinoma; adenocarcinomaDeletion - Frameshift

c.2364C>T; p.V788V; 14:58646987-58646987

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2415C>T; p.P805P; 14:58647038-58647038

 skinmalignant_melanomaSubstitution - coding silent

c.2045C>T; p.S682L; 14:58646668-58646668

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1142C>T; p.P381L; 14:58645765-58645765

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.2038A>T; p.K680*; 14:58646661-58646661

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.2395C>A; p.P799T; 14:58647018-58647018

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1833G>T; p.K611N; 14:58646456-58646456

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1414G>T; p.G472W; 14:58646037-58646037

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.372T>C; p.G124G; 14:58640762-58640762

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2392G>A; p.A798T; 14:58647015-58647015

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1402G>A; p.A468T; 14:58646025-58646025

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.282G>A; p.A94A; 14:58638484-58638484

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1240_1241insC; p.P416fs*35; 14:58645863-58645864

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.2180C>A; p.S727*; 14:58646803-58646803

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1552G>A; p.V518I; 14:58646175-58646175

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1497G>A; p.E499E; 14:58646120-58646120

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.940G>A; p.V314I; 14:58645563-58645563

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2431A>G; p.K811E; 14:58647054-58647054

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.940G>A; p.V314I; 14:58645563-58645563

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.287G>A; p.R96H; 14:58638489-58638489

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2369C>T; p.T790I; 14:58646992-58646992

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1073C>T; p.P358L; 14:58645696-58645696

 breastcarcinomaSubstitution - Missense

c.2007T>G; p.P669P; 14:58646630-58646630

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1326C>T; p.G442G; 14:58645949-58645949

 pancreascarcinomaSubstitution - coding silent

c.1326C>T; p.G442G; 14:58645949-58645949

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2017C>G; p.R673G; 14:58646640-58646640

 livercarcinomaSubstitution - Missense

c.2017C>G; p.R673G; 14:58646640-58646640

 livercarcinomaSubstitution - Missense

c.1817G>T; p.R606L; 14:58646440-58646440

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1557C>A; p.P519P; 14:58646180-58646180

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1284C>T; p.A428A; 14:58645907-58645907

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.508G>T; p.G170*; 14:58641621-58641621

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1708C>T; p.H570Y; 14:58646331-58646331

 skinmalignant_melanomaSubstitution - Missense

c.297_299delGGA; p.E101delE; 14:58638499-58638501

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - In frame

c.2469C>G; p.L823L; 14:58647092-58647092

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1184C>T; p.S395L; 14:58645807-58645807

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.600C>G; p.T200T; 14:58641713-58641713

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.2405A>T; p.H802L; 14:58647028-58647028

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1960G>A; p.G654R; 14:58646583-58646583

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2454C>T; p.L818L; 14:58647077-58647077

 skinmalignant_melanomaSubstitution - coding silent

c.2119G>A; p.A707T; 14:58646742-58646742

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2119G>A; p.A707T; 14:58646742-58646742

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.2396C>A; p.P799Q; 14:58647019-58647019

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1892G>A; p.G631E; 14:58646515-58646515

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2139C>T; p.Y713Y; 14:58646762-58646762

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2139C>T; p.Y713Y; 14:58646762-58646762

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.2139C>T; p.Y713Y; 14:58646762-58646762

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - coding silent

c.1981G>A; p.G661R; 14:58646604-58646604

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1816C>T; p.R606W; 14:58646439-58646439

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1601A>G; p.E534G; 14:58646224-58646224

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1735G>A; p.V579M; 14:58646358-58646358

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.2394C>T; p.A798A; 14:58647017-58647017

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1497G>C; p.E499D; 14:58646120-58646120

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2163T>C; p.A721A; 14:58646786-58646786

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.370G>T; p.G124C; 14:58640760-58640760

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1991C>T; p.A664V; 14:58646614-58646614

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2095C>T; p.R699W; 14:58646718-58646718

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2095C>T; p.R699W; 14:58646718-58646718

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.2151C>T; p.Y717Y; 14:58646774-58646774

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.2050G>A; p.E684K; 14:58646673-58646673

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1475G>A; p.R492K; 14:58646098-58646098

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1475G>A; p.R492K; 14:58646098-58646098

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2107G>C; p.G703R; 14:58646730-58646730

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.585C>A; p.S195R; 14:58641698-58641698

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1627G>T; p.E543*; 14:58646250-58646250

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1293G>A; p.K431K; 14:58645916-58645916

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.536T>C; p.V179A; 14:58641649-58641649

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2121G>A; p.A707A; 14:58646744-58646744

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2121G>A; p.A707A; 14:58646744-58646744

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2121G>A; p.A707A; 14:58646744-58646744

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1615G>T; p.D539Y; 14:58646238-58646238

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2191G>T; p.E731*; 14:58646814-58646814

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1410G>A; p.G470G; 14:58646033-58646033

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1815G>A; p.T605T; 14:58646438-58646438

 pancreascarcinomaSubstitution - coding silent

c.1815G>A; p.T605T; 14:58646438-58646438

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2247C>T; p.Y749Y; 14:58646870-58646870

 breastcarcinomaSubstitution - coding silent

c.1719C>A; p.H573Q; 14:58646342-58646342

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1762G>A; p.G588S; 14:58646385-58646385

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.2172C>T; p.S724S; 14:58646795-58646795

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1011A>C; p.K337N; 14:58645634-58645634

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2046G>A; p.S682S; 14:58646669-58646669

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.786C>T; p.N262N; 14:58645409-58645409

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2048C>A; p.A683D; 14:58646671-58646671

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1087A>T; p.N363Y; 14:58645710-58645710

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1435G>A; p.A479T; 14:58646058-58646058

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.886G>T; p.D296Y; 14:58645509-58645509

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2089G>A; p.G697S; 14:58646712-58646712

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2457G>A; p.K819K; 14:58647080-58647080

 skinmalignant_melanomaSubstitution - coding silent

c.2089G>A; p.G697S; 14:58646712-58646712

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2089G>A; p.G697S; 14:58646712-58646712

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1755G>A; p.K585K; 14:58646378-58646378

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.659A>C; p.K220T; 14:58645282-58645282

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2428G>T; p.V810F; 14:58647051-58647051

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.2428G>T; p.V810F; 14:58647051-58647051

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1671C>T; p.A557A; 14:58646294-58646294

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.541_544delAGTG; p.E182fs*19; 14:58641654-58641657

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.493A>C; p.S165R; 14:58641606-58641606

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.2144G>C; p.S715T; 14:58646767-58646767

 kidneyother; neoplasmSubstitution - Missense

c.975T>G; p.S325R; 14:58645598-58645598

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.230G>T; p.G77V; 14:58638432-58638432

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.988T>G; p.S330A; 14:58645611-58645611

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.621C>G; p.C207W; 14:58641734-58641734

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1048A>G; p.T350A; 14:58645671-58645671

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.569G>T; p.S190I; 14:58641682-58641682

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1594G>A; p.V532M; 14:58646217-58646217

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1193C>T; p.A398V; 14:58645816-58645816

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.802C>T; p.R268C; 14:58645425-58645425

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1500C>T; p.N500N; 14:58646123-58646123

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.754C>A; p.P252T; 14:58645377-58645377

 skinmalignant_melanomaSubstitution - Missense

c.2191G>A; p.E731K; 14:58646814-58646814

 stomachadenocarcinomaSubstitution - Missense

c.2258G>A; p.C753Y; 14:58646881-58646881

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1083C>T; p.S361S; 14:58645706-58645706

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1985G>C; p.R662P; 14:58646608-58646608

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1555C>T; p.P519S; 14:58646178-58646178

 skinmalignant_melanomaSubstitution - Missense

c.1800C>T; p.T600T; 14:58646423-58646423

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2140G>T; p.A714S; 14:58646763-58646763

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1260G>A; p.S420S; 14:58645883-58645883

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1092T>A; p.A364A; 14:58645715-58645715

 lung; left_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1492C>A; p.Q498K; 14:58646115-58646115

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1684G>T; p.G562W; 14:58646307-58646307

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1136G>T; p.R379I; 14:58645759-58645759

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2429T>C; p.V810A; 14:58647052-58647052

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1134C>T; p.V378V; 14:58645757-58645757

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1134C>T; p.V378V; 14:58645757-58645757

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1777G>A; p.G593R; 14:58646400-58646400

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1615G>A; p.D539N; 14:58646238-58646238

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.1327G>A; p.A443T; 14:58645950-58645950

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.691G>A; p.A231T; 14:58645314-58645314

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1163A>G; p.N388S; 14:58645786-58645786

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.387G>A; p.L129L; 14:58640777-58640777

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1682C>T; p.P561L; 14:58646305-58646305

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2023G>A; p.D675N; 14:58646646-58646646

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1142C>A; p.P381Q; 14:58645765-58645765

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1142C>A; p.P381Q; 14:58645765-58645765

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1062G>T; p.R354S; 14:58645685-58645685

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2298C>T; p.F766F; 14:58646921-58646921

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2210_2211CC>TT; p.T737I; 14:58646833-58646834

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.483T>G; p.F161L; 14:58641596-58641596

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.830C>T; p.A277V; 14:58645453-58645453

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.310T>A; p.L104M; 14:58638512-58638512

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1596G>T; p.V532V; 14:58646219-58646219

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.2204A>G; p.H735R; 14:58646827-58646827

 skinmalignant_melanomaSubstitution - Missense

c.1241C>A; p.S414Y; 14:58645864-58645864

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2029C>T; p.R677W; 14:58646652-58646652

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2029C>T; p.R677W; 14:58646652-58646652

 skinmalignant_melanomaSubstitution - Missense

c.704delC; p.L236fs*15; 14:58645327-58645327

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.2236C>T; p.Q746*; 14:58646859-58646859

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.2236C>T; p.Q746*; 14:58646859-58646859

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

')