Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

51339

Name

DACT1

Synonymous

DAPPER|DAPPER1|DPR1|FRODO|HDPR1|THYEX3;dishevelled-binding antagonist of beta-catenin 1;DACT1;dishevelled-binding antagonist of beta-catenin 1

Definition

dapper antagonist of catenin 1|dapper homolog 1|dapper, antagonist of beta-catenin, homolog 1|hepatocellular carcinoma novel gene 3 protein|heptacellular carcinoma novel gene 3

Position

14q23.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Dpr1(h) --/ Dvl-2(m.s.) (decrease of abundance)
Dpr1(h) + LEF-1(m.s.) <==> Dpr1(h):LEF-1(m.s.) (binding)
Dpr1(h) + beta-catenin(h) <==> Dpr1(h):beta-catenin(h) (binding)
Dpr1(h) + beta-catenin(m.s.) <==> Dpr1(h):beta-catenin(m.s.) (binding)
Dpr1(h) + HDAC1(m.s.) <==> Dpr1(h):HDAC1(m.s.) (binding)
DACT1(h) --> Dpr1(h) (expression).
Dpr1(h) --> Dpr1(h) (translocation)
Dpr1(h) + beta-catenin(h) <==> Dpr1(h):beta-catenin(h) (binding)
Dpr1(h) + HDAC1(h) <==> Dpr1(h):HDAC1(h) (binding)
Dpr1(h) --/ c-myc(h) (transrepression)
Dpr1(h) --/ CCND1(h) (transrepression)
DACT1(h) --> Dpr1(h) (expression).
Dpr1(h) --> Dpr1(h) (translocation)

Post Transcriptional Modification   [Top]

There is no record for DACT1

Methylation Profile   [Top]

Chromosome

Location

Source

chr14

Promoter: 58173010 - 58175010Agilent_014791

chr14

Promoter: 58173010 - 58175010GSE27584

chr14

Promoter: 58173010 - 58175010GSE27584

chr14

Promoter: 58173010 - 58175010Agilent_014791_44K

chr14

Promoter: 58173010 - 58175010PMID:15580286

chr14

Promoter: 58173010 - 58175010PMID:15580286


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