Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	56849
Name	TCEAL7
Synonymous	transcription elongation factor A (SII)-like 7;TCEAL7;transcription elongation factor A (SII)-like 7
Definition	TCEA-like protein 7\|transcription elongation factor A protein-like 7\|transcription elongation factor S-II protein-like 7
Position	Xq22.1
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

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We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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The non-synonymous mutational pattern in 17 major cancer types.

The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

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Loss of Function mutations compare to missense mutation.

The ratio of the loss-of-function mutations over missense mutations is 0.17.

The copy number variations for various cancers

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There is no record for TCEAL7

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.84T>G; p.F28L; 23:103331487-103331487	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.188C>A; p.T63K; 23:103331591-103331591	liver	carcinoma	Substitution - Missense
c.188C>A; p.T63K; 23:103331591-103331591	liver	carcinoma	Substitution - Missense
c.259C>A; p.H87N; 23:103331662-103331662	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.55A>T; p.R19W; 23:103331458-103331458	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.55A>T; p.R19W; 23:103331458-103331458	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.85G>C; p.E29Q; 23:103331488-103331488	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.250A>G; p.R84G; 23:103331653-103331653	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.139G>T; p.E47*; 23:103331542-103331542	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.139G>T; p.E47*; 23:103331542-103331542	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.278C>A; p.S93Y; 23:103331681-103331681	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.152A>G; p.D51G; 23:103331555-103331555	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.148G>C; p.E50Q; 23:103331551-103331551	skin	malignant_melanoma	Substitution - Missense
c.266A>C; p.N89T; 23:103331669-103331669	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.136G>A; p.E46K; 23:103331539-103331539	skin	malignant_melanoma	Substitution - Missense
c.139G>A; p.E47K; 23:103331542-103331542	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.248T>G; p.F83C; 23:103331651-103331651	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense

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