Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6793

Name

STK10

Synonymous

serine/threonine kinase 10;STK10;serine/threonine kinase 10

Definition

lymphocyte-oriented kinase|serine/threonine-protein kinase 10

Position

5q35.1

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Top

The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

Top

Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.07.

The copy number variations for various cancers

Top

The copy number variations in 17 major cancer groups: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1066A>C; p.K356Q; 5:172093900-172093900

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1675A>T; p.R559*; 5:172090242-172090242

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1539C>A; p.G513G; 5:172093427-172093427

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.317T>A; p.L106Q; 5:172156628-172156628

 skinmalignant_melanomaSubstitution - Missense

c.1651G>A; p.D551N; 5:172090266-172090266

 skinmalignant_melanomaSubstitution - Missense

c.352G>A; p.V118M; 5:172127391-172127391

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.999C>T; p.A333A; 5:172096432-172096432

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1986A>G; p.K662K; 5:172082329-172082329

 livercarcinomaSubstitution - coding silent

c.1698C>T; p.L566L; 5:172083072-172083072

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2587G>A; p.E863K; 5:172054634-172054634

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1969C>T; p.L657F; 5:172082346-172082346

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.991G>A; p.V331M; 5:172096440-172096440

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1606G>A; p.D536N; 5:172090311-172090311

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.1777C>G; p.Q593E; 5:172082993-172082993

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2619T>C; p.C873C; 5:172054602-172054602

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.2619T>C; p.C873C; 5:172054602-172054602

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1543C>G; p.L515V; 5:172093423-172093423

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1436G>A; p.G479E; 5:172093530-172093530

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2161A>T; p.I721F; 5:172061190-172061190

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.761C>T; p.P254L; 5:172106647-172106647

 breastcarcinomaSubstitution - Missense

c.1094C>T; p.P365L; 5:172093872-172093872

 peritoneum; appendixother; pseudomyxoma_peritoneiSubstitution - Missense

c.1094C>T; p.P365L; 5:172093872-172093872

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.2216G>A; p.R739Q; 5:172057470-172057470

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1475C>T; p.T492I; 5:172093491-172093491

 skinmalignant_melanomaSubstitution - Missense

c.2449C>T; p.R817C; 5:172055665-172055665

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2083-1G>T; p.?; 5:172061269-172061269

 lungcarcinoma; adenocarcinomaUnknown

c.46G>A; p.E16K; 5:172187997-172187997

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.2103G>A; p.K701K; 5:172061248-172061248

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.909G>A; p.L303L; 5:172096522-172096522

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1587G>C; p.R529R; 5:172090330-172090330

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.793G>A; p.V265I; 5:172105733-172105733

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2683G>A; p.E895K; 5:172053012-172053012

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1555-1G>T; p.?; 5:172090363-172090363

 stomachcarcinoma; adenocarcinomaUnknown

c.1942C>T; p.R648W; 5:172082373-172082373

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1383T>G; p.G461G; 5:172093583-172093583

 breastcarcinomaSubstitution - coding silent

c.111G>T; p.E37D; 5:172187932-172187932

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.640T>A; p.Y214N; 5:172106768-172106768

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaSubstitution - Missense

c.2392C>T; p.R798W; 5:172055722-172055722

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.104T>C; p.V35A; 5:172187939-172187939

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.467G>A; p.R156Q; 5:172117534-172117534

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.879C>T; p.F293F; 5:172096552-172096552

 skinmalignant_melanomaSubstitution - coding silent

c.1192C>A; p.P398T; 5:172093774-172093774

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1000G>A; p.A334T; 5:172096431-172096431

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.879C>T; p.F293F; 5:172096552-172096552

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1591C>T; p.R531C; 5:172090326-172090326

 breastcarcinomaSubstitution - Missense

c.667C>A; p.L223M; 5:172106741-172106741

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1560G>A; p.P520P; 5:172090357-172090357

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1591C>T; p.R531C; 5:172090326-172090326

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1560G>A; p.P520P; 5:172090357-172090357

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.2124G>C; p.L708L; 5:172061227-172061227

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.385C>A; p.L129I; 5:172117616-172117616

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2905T>G; p.*969E; 5:172044884-172044884

 urinary_tract; bladdercarcinomaNonstop extension

c.1147T>G; p.S383A; 5:172093819-172093819

 skinmalignant_melanomaSubstitution - Missense

c.385C>A; p.L129I; 5:172117616-172117616

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.466C>T; p.R156*; 5:172117535-172117535

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2016C>T; p.P672P; 5:172064786-172064786

 skinmalignant_melanomaSubstitution - coding silent

c.2882C>A; p.P961H; 5:172044907-172044907

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.2301C>T; p.F767F; 5:172057385-172057385

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2485G>A; p.G829S; 5:172055629-172055629

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1708C>T; p.R570W; 5:172083062-172083062

 skinmalignant_melanomaSubstitution - Missense

c.1246G>A; p.V416M; 5:172093720-172093720

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1708C>T; p.R570W; 5:172083062-172083062

 skinmalignant_melanomaSubstitution - Missense

c.2146G>A; p.D716N; 5:172061205-172061205

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1267C>T; p.Q423*; 5:172093699-172093699

 skinmalignant_melanomaSubstitution - Nonsense

c.2484C>T; p.N828N; 5:172055630-172055630

 breastcarcinomaSubstitution - coding silent

c.98A>G; p.N33S; 5:172187945-172187945

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.359C>T; p.A120V; 5:172127384-172127384

 skinmalignant_melanomaSubstitution - Missense

c.777G>A; p.T259T; 5:172106631-172106631

 breastcarcinomaSubstitution - coding silent

c.1182A>C; p.P394P; 5:172093784-172093784

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.911G>T; p.R304L; 5:172096520-172096520

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.777G>A; p.T259T; 5:172106631-172106631

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.501C>T; p.L167L; 5:172117500-172117500

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.238G>A; p.V80M; 5:172156707-172156707

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1453T>C; p.S485P; 5:172093513-172093513

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.534G>A; p.V178V; 5:172107839-172107839

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.585G>A; p.T195T; 5:172107788-172107788

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2599C>T; p.R867W; 5:172054622-172054622

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1454C>T; p.S485L; 5:172093512-172093512

 skinmalignant_melanomaSubstitution - Missense

c.2178C>T; p.R726R; 5:172061173-172061173

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.761C>A; p.P254H; 5:172106647-172106647

 skinmalignant_melanomaSubstitution - Missense

c.2310G>T; p.R770R; 5:172057376-172057376

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2712G>A; p.E904E; 5:172052983-172052983

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1325A>G; p.N442S; 5:172093641-172093641

 pancreasNSSubstitution - Missense

c.506G>A; p.G169E; 5:172117495-172117495

 skinmalignant_melanomaSubstitution - Missense

c.1990-1G>T; p.?; 5:172064813-172064813

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.2527-1G>T; p.?; 5:172054695-172054695

 pancreascarcinomaUnknown

c.2158G>A; p.E720K; 5:172061193-172061193

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2158G>A; p.E720K; 5:172061193-172061193

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2620G>A; p.E874K; 5:172054601-172054601

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.2620G>A; p.E874K; 5:172054601-172054601

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.2620G>A; p.E874K; 5:172054601-172054601

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.730C>T; p.R244W; 5:172106678-172106678

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.291G>T; p.L97L; 5:172156654-172156654

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.2565G>T; p.R855R; 5:172054656-172054656

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1389G>T; p.E463D; 5:172093577-172093577

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.254T>A; p.L85Q; 5:172156691-172156691

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2544G>A; p.E848E; 5:172054677-172054677

 skinmalignant_melanomaSubstitution - coding silent

c.1687C>T; p.R563C; 5:172083083-172083083

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2125G>C; p.A709P; 5:172061226-172061226

 breastcarcinomaSubstitution - Missense

c.2353C>T; p.Q785*; 5:172055761-172055761

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Nonsense

c.1070C>T; p.P357L; 5:172093896-172093896

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1157G>T; p.R386I; 5:172093809-172093809

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.693C>G; p.A231A; 5:172106715-172106715

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1866G>A; p.Q622Q; 5:172082449-172082449

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1230delG; p.R411fs*14; 5:172093736-172093736

 ovarycarcinoma; serous_carcinomaDeletion - Frameshift

c.358G>A; p.A120T; 5:172127385-172127385

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.294A>C; p.G98G; 5:172156651-172156651

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.520G>T; p.A174S; 5:172117481-172117481

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1531G>C; p.E511Q; 5:172093435-172093435

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.990C>T; p.A330A; 5:172096441-172096441

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2088G>T; p.R696R; 5:172061263-172061263

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2834C>T; p.A945V; 5:172044955-172044955

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2832G>A; p.E944E; 5:172044957-172044957

 breastcarcinoma; ER-PR-positive_carcinomaSubstitution - coding silent

c.1366G>A; p.A456T; 5:172093600-172093600

 central_nervous_system; braingliomaSubstitution - Missense

c.2155C>T; p.R719W; 5:172061196-172061196

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.2790G>C; p.Q930H; 5:172044999-172044999

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.307G>A; p.D103N; 5:172156638-172156638

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1699C>T; p.R567*; 5:172083071-172083071

 skinmalignant_melanomaSubstitution - Nonsense

c.2700G>T; p.K900N; 5:172052995-172052995

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2613G>A; p.A871A; 5:172054608-172054608

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1705C>A; p.L569I; 5:172083065-172083065

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2867C>T; p.A956V; 5:172044922-172044922

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2694A>C; p.K898N; 5:172053001-172053001

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1437G>T; p.G479G; 5:172093529-172093529

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2869G>T; p.A957S; 5:172044920-172044920

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.202G>A; p.E68K; 5:172156743-172156743

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; chronic_myeloid_leukaemiaSubstitution - Missense

c.315G>A; p.K105K; 5:172156630-172156630

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.254T>C; p.L85P; 5:172156691-172156691

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.2733G>A; p.K911K; 5:172052962-172052962

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.2733G>A; p.K911K; 5:172052962-172052962

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1177C>T; p.P393S; 5:172093789-172093789

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2586C>A; p.H862Q; 5:172054635-172054635

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.2688C>A; p.T896T; 5:172053007-172053007

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1226C>G; p.P409R; 5:172093740-172093740

 skinmalignant_melanomaSubstitution - Missense

c.904G>A; p.A302T; 5:172096527-172096527

 skinmalignant_melanomaSubstitution - Missense

c.1716C>T; p.L572L; 5:172083054-172083054

 skinmalignant_melanomaSubstitution - coding silent

c.1046C>T; p.P349L; 5:172093920-172093920

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.1809+1G>T; p.?; 5:172082960-172082960

 lungcarcinoma; adenocarcinomaUnknown

c.2620G>C; p.E874Q; 5:172054601-172054601

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.744G>T; p.K248N; 5:172106664-172106664

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1368C>A; p.A456A; 5:172093598-172093598

 upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1060G>T; p.A354S; 5:172093906-172093906

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2550G>T; p.R850S; 5:172054671-172054671

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2808G>T; p.E936D; 5:172044981-172044981

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.767_768CG>TT; p.T256I; 5:172106640-172106641

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1576delA; p.T526fs*15; 5:172090341-172090341

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.2323C>T; p.R775C; 5:172057363-172057363

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1057A>T; p.N353Y; 5:172093909-172093909

 breastcarcinomaSubstitution - Missense

c.1688G>A; p.R563H; 5:172083082-172083082

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.2634C>T; p.S878S; 5:172054587-172054587

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1022C>G; p.T341S; 5:172093944-172093944

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.2290G>T; p.D764Y; 5:172057396-172057396

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1019A>G; p.H340R; 5:172093947-172093947

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2656G>A; p.E886K; 5:172053039-172053039

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1518G>T; p.L506L; 5:172093448-172093448

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.1518G>T; p.L506L; 5:172093448-172093448

 prostatecarcinomaSubstitution - coding silent

c.783T>C; p.S261S; 5:172106625-172106625

 thyroidother; neoplasmSubstitution - coding silent

c.1095G>A; p.P365P; 5:172093871-172093871

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2826C>T; p.S942S; 5:172044963-172044963

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.204A>C; p.E68D; 5:172156741-172156741

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.2064G>A; p.T688T; 5:172064738-172064738

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.194A>G; p.K65R; 5:172156751-172156751

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.2587G>C; p.E863Q; 5:172054634-172054634

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2880C>T; p.F960F; 5:172044909-172044909

 skinmalignant_melanomaSubstitution - coding silent

c.1521G>A; p.S507S; 5:172093445-172093445

 bone; pelvisEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1783C>A; p.H595N; 5:172082987-172082987

 thyroidother; neoplasmSubstitution - Missense

c.907C>A; p.L303M; 5:172096524-172096524

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.2130G>A; p.M710I; 5:172061221-172061221

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.914A>C; p.E305A; 5:172096517-172096517

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2009A>G; p.K670R; 5:172064793-172064793

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1386G>T; p.G462G; 5:172093580-172093580

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.643G>T; p.D215Y; 5:172106765-172106765

 livercarcinomaSubstitution - Missense

c.643G>T; p.D215Y; 5:172106765-172106765

 livercarcinomaSubstitution - Missense

c.2588A>G; p.E863G; 5:172054633-172054633

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2588A>G; p.E863G; 5:172054633-172054633

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2106G>C; p.Q702H; 5:172061245-172061245

 breastcarcinomaSubstitution - Missense

c.2654A>C; p.N885T; 5:172053041-172053041

 livercarcinomaSubstitution - Missense

c.2654A>C; p.N885T; 5:172053041-172053041

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1592G>A; p.R531H; 5:172090325-172090325

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1321G>A; p.A441T; 5:172093645-172093645

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2010G>T; p.K670N; 5:172064792-172064792

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1897G>A; p.V633M; 5:172082418-172082418

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1833G>A; p.T611T; 5:172082482-172082482

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2209C>T; p.R737*; 5:172061142-172061142

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2101A>C; p.K701Q; 5:172061250-172061250

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.829A>G; p.K277E; 5:172105697-172105697

 testisgerm_cell_tumour; seminomaSubstitution - Missense

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