| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6793 |
Name | STK10 |
Synonymous | LOK|PRO2729;serine/threonine kinase 10;STK10;serine/threonine kinase 10 |
Definition | lymphocyte-oriented kinase|serine/threonine-protein kinase 10 |
Position | 5q35.1 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
LOK(h) + ATP --> LOK(h){p} + ADP (phosphorylation; automodification) | plk1(h) + LOK(h) <==> plk1(h):LOK(h) (binding) | STK10(h) --> LOK(h) (expression). | histone H2A(v.s.) + ATP --LOK(h)--> histone H2A(v.s.){p} + ADP (phosphorylation) | plk1(v.s.) + ATP --LOK(h)--> plk1(v.s.){p} + ADP (phosphorylation) | STK10(h) --> LOK(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
438 | Phosphoserine. | Swiss-Prot 53.0 | 438 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr5 |
Promoter: 171547365 - 171549365 | Agilent_014791 |
chr5 |
Promoter: 171547365 - 171549365 | GSE27584 |
chr5 |
Promoter: 171547365 - 171549365 | Agilent_014791_44K |