Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	92304
Name	SCGB3A1
Synonymous	secretoglobin, family 3A, member 1;SCGB3A1;secretoglobin, family 3A, member 1
Definition	cytokine HIN-1\|cytokine high in normal-1\|high in normal 1\|pneumo secretory protein 2\|secretoglobin family 3A member 1\|uteroglobin-related protein 2
Position	5q35.3
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

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We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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The non-synonymous mutational pattern in 17 major cancer types.

The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

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Loss of Function mutations compare to missense mutation.

The ratio of the loss-of-function mutations over missense mutations is 0.00.

The copy number variations for various cancers

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There is no record for SCGB3A1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.167C>T; p.P56L; 5:180590724-180590724	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.201delC; p.V68fs*1; 5:180590690-180590690	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.151C>T; p.L51F; 5:180590740-180590740	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.63C>T; p.F21F; 5:180590828-180590828	skin	malignant_melanoma	Substitution - coding silent
c.63C>T; p.F21F; 5:180590828-180590828	skin	malignant_melanoma	Substitution - coding silent
c.119C>T; p.A40V; 5:180590772-180590772	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.85G>T; p.V29L; 5:180590806-180590806	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.215T>C; p.I72T; 5:180590676-180590676	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.128G>A; p.G43E; 5:180590763-180590763	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense

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