| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 9521 |
Name | EEF1E1 |
Synonymous | eukaryotic translation elongation factor 1 epsilon 1;EEF1E1;eukaryotic translation elongation factor 1 epsilon 1 |
Definition | ARS-interacting multifunctional protein 3|aminoacyl tRNA synthetase complex-interacting multifunctional protein 3|eukaryotic translation elongation factor 1 epsilon-1|multisynthase complex auxiliary component p18|p18 component of aminoacyl-tRNA synthetase |
Position | 6p24.3 |
Gene Type | protein-coding |
Mutation summary: | Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72 |
Mutation summary in protein domains | Top |
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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers | Top |
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Loss of Function mutations compare to missense mutations | Top |
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| The ratio of the loss-of-function mutations over missense mutations is 0.00. |
The copy number variations for various cancers | Top |
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The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
COSMIC somatic mutation [Top] | |||
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Mutation (CDS; AA; Chr) |
Site |
Histology |
Mutation Type |
|---|---|---|---|
c.210C>T; p.I70I; 6:8097345-8097345 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.210C>T; p.I70I; 6:8097345-8097345 |
skin | malignant_melanoma | Substitution - coding silent |
c.242A>T; p.Q81L; 6:8097313-8097313 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.266A>G; p.N89S; 6:8097289-8097289 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.330G>A; p.G110G; 6:8090240-8090240 |
biliary_tract; bile_duct | carcinoma; adenocarcinoma | Substitution - coding silent |
c.426G>T; p.V142V; 6:8079989-8079989 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - coding silent |
c.426G>T; p.V142V; 6:8079989-8079989 |
liver | carcinoma | Substitution - coding silent |
c.426G>T; p.V142V; 6:8079989-8079989 |
liver | carcinoma | Substitution - coding silent |
c.62A>C; p.K21T; 6:8102460-8102460 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.106A>G; p.N36D; 6:8097449-8097449 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.320A>G; p.Y107C; 6:8090250-8090250 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.263A>G; p.K88R; 6:8097292-8097292 |
skin | malignant_melanoma | Substitution - Missense |
c.119G>T; p.S40I; 6:8097436-8097436 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.220T>C; p.W74R; 6:8097335-8097335 |
large_intestine; colon | carcinoma | Substitution - Missense |
c.220T>C; p.W74R; 6:8097335-8097335 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.128G>A; p.G43E; 6:8097427-8097427 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.304C>A; p.L102I; 6:8090266-8090266 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.458C>T; p.P153L; 6:8079957-8079957 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.374A>T; p.H125L; 6:8090196-8090196 |
eye; uveal_tract | malignant_melanoma; spindle | Substitution - Missense |
c.252G>A; p.G84G; 6:8097303-8097303 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.184G>T; p.G62W; 6:8097371-8097371 |
prostate | carcinoma; adenocarcinoma | Substitution - Missense |
c.191C>T; p.T64I; 6:8097364-8097364 |
prostate | carcinoma; adenocarcinoma | Substitution - Missense |