Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1028

Name

CDKN1C

Synonymous

BWCR|BWS|KIP2|WBS|p57|p57Kip2;cyclin-dependent kinase inhibitor 1C (p57, Kip2);CDKN1C;cyclin-dependent kinase inhibitor 1C (p57, Kip2)

Definition

cyclin-dependent kinase inhibitor 1C|cyclin-dependent kinase inhibitor p57

Position

11p15.5

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

CDKN1C(h) --> p57Kip2(h) (expression).
TGFbeta1(m.s.) --> p57Kip2(h) (increase of abundance)
TGFbeta2(m.s.) --> p57Kip2(h) (increase of abundance)
CDKN1C(h) --> p57Kip2(h) (expression).
hsa-miR-221 --/ p57Kip2(h) (translational repression).
hsa-miR-222 --/ p57Kip2(h) (translational repression).
CDKN1C(h) --> p57Kip2-long(h) (expression).
CDKN1C(h) --> p57Kip2-short(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for CDKN1C

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

 Promoter: 2863037 - 2865037Agilent_014791

chr11

 Promoter: 2863037 - 2865037GoldenGate_Methylation_Cancer_Panel_I

chr11

 Promoter: 2863037 - 2865037GSE27584

chr11

 Promoter: 2863037 - 2865037Agilent_014791_44K

chr11

 Promoter: 2863037 - 2865037E-GEOD-20553

chr11

 Promoter: 2863037 - 2865037PMID:15198948

chr11

 Promoter: 2863037 - 2865037PMID:16192589

chr11

 Promoter: 2863037 - 2865037PMID:11965547

chr11

 Promoter: 2863037 - 2865037PMID:16357845

chr11

 Promoter: 2863037 - 2865037PMID:15492797

chr11

 Promoter: 2863037 - 2865037PMID:15899813

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