Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

10664

Name

CTCF

Synonymous

MRD21;CCCTC-binding factor (zinc finger protein);CTCF;CCCTC-binding factor (zinc finger protein)

Definition

11 zinc finger transcriptional repressor|11-zinc finger protein|CTCFL paralog|transcriptional repressor CTCF

Position

16q21-q22.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ctcf(h) --> APP(h) (DNA binding).
ctcf(h) --> BRCA1(h) (DNA binding).
ctcf(h) --> c-myc(c) (DNA binding).
ctcf(h) --> RB1(h) (DNA binding).
ctcf(h) --> Hbb-ar(m) (DNA binding).
ctcf(h) --> HBB(c) (DNA binding).
ctcf(h) --> HBB(h) (DNA binding).
ctcf(h) --> Hbb-b1(m) (DNA binding).
ctcf(h) --> TCR-alpha(m) (DNA binding).
ctcf(h) --> IGF2(h) (DNA binding).
ctcf(h) --> Igf2(m) (DNA binding).
ctcf(h) --> H19(h) (DNA binding).
ctcf(h) --> Kcnq1ot1(m) (DNA binding).
ctcf(h) --> CFTR(h) (DNA binding).
Ctcf(h) --> ctcf(h) (expression).
ctcf(h) --> c-myc(h) (DNA binding).
ctcf(h) --> c-myc(m) (DNA binding).
ctcf(h) --> c-myc(c) (DNA binding).
ctcf(h) --/ TERT(h) (DNA binding; transrepression).
T3R-alpha(c) + ctcf(h) <==> T3R-alpha(c):ctcf(h) (binding)
ctcf(h) + RXR-beta(h) <==> ctcf(h):RXR-beta(h) (binding)
ctcf(h) --> APP(h) (DNA binding).
ctcf(h) --> Gtf2a1l(m) (DNA binding).
ctcf(h) --> HBB(c) (DNA binding).
2 ctcf(h) <==> (ctcf(h))2 (binding)
nucleophosmin(h) + ctcf(h) <==> nucleophosmin(h):ctcf(h) (binding)
ctcf(h) --> LYS(c) (DNA binding).
ctcf(h) --> PIM1(h) (DNA binding).
ctcf(h) --> H19(m) (DNA binding).
ctcf(h) --> PLK1(h) (DNA binding).
ctcf(h) --> CDKN2A(m) (DNA binding).
ctcf(h) --> MYC(c) (DNA binding).
ctcf(h) --> Kcnq1ot1(m) (DNA binding).
Ctcf(h) --> ctcf(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

609Phosphoserine.Swiss-Prot 53.0
610Phosphoserine.Swiss-Prot 53.0
612Phosphoserine.Swiss-Prot 53.0
609Phosphoserine17081983Phospho.ELM 6.0
610Phosphoserine17081983Phospho.ELM 6.0
612Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr16

Promoter: 66152465 - 66154465Agilent_014791

chr16

Promoter: 66152465 - 66154465GSE27584

chr16

Promoter: 66152465 - 66154465Agilent_014791_44K


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