Entrez Gene

Basic Information
Gene ID	150094
Name	SIK1
Synonymous	EIEE30\|MSK\|SIK\|SNF1LK;salt-inducible kinase 1;SIK1;salt-inducible kinase 1
Definition	SIK-1\|SNF1-like kinase\|myocardial SNF1-like kinase\|salt-inducible protein kinase 1\|serine/threonine protein kinase\|serine/threonine-protein kinase SIK1\|serine/threonine-protein kinase SNF1-like kinase 1\|serine/threonine-protein kinase SNF1LK
Position	21q22.3
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
SIK(h) + ATP --LKB1(m):STRADalpha(h):MO25(h)--> SIK(h){pT182} + ADP (phosphorylation)
SIK(h) + ATP --LKB1(m):STRADalpha(h):MO25beta(h)--> SIK(h){pT182} + ADP (phosphorylation)
SIK(h) + ATP --LKB1(m):STRADbeta(h):MO25(h)--> SIK(h){pT182} + ADP (phosphorylation)
SIK(h) + ATP --LKB1(m.s.)--> SIK(h){pT182} + ADP (phosphorylation)
SIK(h) + ATP --LKB1(m.s.):STRADbeta(m.s.):MO25(m.s.)--> SIK(h){pT182} + ADP (phosphorylation)
SIK(h) + 14-3-3zeta(h) <==> SIK(h):14-3-3zeta(h) (binding)
Snf1lk(h) --> SIK(h) (expression).
SIK(h) + 14-3-3zeta(h) <==> SIK(h):14-3-3zeta(h) (binding)
14-3-3epsilon(h) + 14-3-3zeta(h) + alpha-tubulin 1B(h) + Hsp70-1(h) + SIK(h) <==> 14-3-3epsilon(h):14-3-3zeta(h):alpha-tubulin 1B(h):Hsp70-1(h):SIK(h) (binding)
Snf1lk(h) --> SIK(h) (expression).
TORC2(h) + ATP --SIK(h)--> TORC2(h){pS70}{pS171}{pS348} + ADP (phosphorylation)

Post Transcriptional Modification [Top]
	There is no record for SIK1