| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1643 |
Name | DDB2 |
Synonymous | DDBB|UV-DDB2;damage-specific DNA binding protein 2, 48kDa;DDB2;damage-specific DNA binding protein 2, 48kDa |
Definition | DDB p48 subunit|DNA damage-binding protein 2|UV-DDB 2|UV-damaged DNA-binding protein 2|damage-specific DNA-binding protein 2|xeroderma pigmentosum group E protein |
Position | 11p12-p11 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
SUMO2(h) + DDB-2(h) --> DDB-2(h){sumo2} (sumoylation) | histone H2A(h){ub} + DDB-2(h) <==> histone H2A(h){ub}:DDB-2(h) (binding) | histone H2A(h) + DDB-2(h) <==> histone H2A(h):DDB-2(h) (binding) | Roc1(h) + CUL4A(h) + DDB-2(h) + DDB1(h) <==> Roc1(h):CUL4A(h):DDB-2(h):DDB1(h) (binding) | DDB2(h) --> DDB-2(h) (expression). | DDB-2-isoform1(h) + CUL4A-isoform2(h) <==> DDB-2-isoform1(h):CUL4A-isoform2(h) (binding) | DDB-2-isoform1(h) + DDB1(h) <==> DDB-2-isoform1(h):DDB1(h) (binding) | DDB-2-isoform1(h) + DDB1(h):CUL4A-isoform2(h) <==> DDB-2-isoform1(h):DDB1(h):CUL4A-isoform2(h) (binding) | DDB2(h) --> DDB-2-isoform1(h) (expression). | DDB2(h) --> DDB-2-isoform-D1(h) (expression). | DDB2(h) --> DDB-2-isoform-D2(h) (expression). | DDB2(h) --> DDB-2-isoform-D3(h) (expression). | DDB2(h) --> DDB-2-isoform-D4(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
24 | Phosphoserine. | Swiss-Prot 53.0 | 26 | Phosphoserine. | Swiss-Prot 53.0 | 24 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 26 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 47191589 - 47193589 | Agilent_014791 |
chr11 |
Promoter: 47191589 - 47193589 | GoldenGate_Methylation_Cancer_Panel_I |
chr11 |
Promoter: 47191589 - 47193589 | GSE27584 |
chr11 |
Promoter: 47191589 - 47193589 | Agilent_014791 |
chr11 |
Promoter: 47191589 - 47193589 | PMID:15899813 |