| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1647 |
Name | GADD45A |
Synonymous | DDIT1|GADD45;growth arrest and DNA-damage-inducible, alpha;GADD45A;growth arrest and DNA-damage-inducible, alpha |
Definition | DDIT-1|DNA damage-inducible transcript 1 protein|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|growth arrest and DNA damage-inducible protein GADD45 alpha|growth arrest and DNA-damage-inducible 45 alpha |
Position | 1p31.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
GADD45-alpha(h) + Cdk1(h) <==> GADD45-alpha(h):Cdk1(h) (binding) | GADD45-alpha(h) + PCNA(h) <==> GADD45-alpha(h):PCNA(h) (binding) | GADD45-alpha(h) + p21Cip1(h) <==> GADD45-alpha(h):p21Cip1(h) (binding) | GADD45-alpha(h) --> cyclinB1(h):Cdk1(h) (decrease of binding) | GADD45A(h) --> GADD45-alpha(h) (expression). | GADD45-alpha(h) + PPARgamma2(m) <==> GADD45-alpha(h):PPARgamma2(m) (binding) | GADD45-alpha(h) + PPARdelta(m) <==> GADD45-alpha(h):PPARdelta(m) (binding) | GADD45-alpha(h) + PPARalpha(m) <==> GADD45-alpha(h):PPARalpha(m) (binding) | GADD45-alpha(h) + ER-alpha(h) <==> GADD45-alpha(h):ER-alpha(h) (binding) | GADD45-alpha(h) + NR1B1(h) <==> GADD45-alpha(h):NR1B1(h) (binding) | GADD45-alpha(h) + RXR-alpha(h) <==> GADD45-alpha(h):RXR-alpha(h) (binding) | GADD45-alpha(h) --> c-Jun(m.s.){p} (increase of phosphorylation) | GADD45-alpha(h) + dynactin 2(h) <==> GADD45-alpha(h):dynactin 2(h) (binding) | GADD45A(h) --> GADD45-alpha(h) (expression). | Apak(h) --/ GADD45-alpha(h) (decrease of abundance) |
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Post Transcriptional Modification [Top] | |||
There is no record for GADD45A | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr1 |
Promoter: 67921971 - 67923971 | Agilent_014791 |
chr1 |
Promoter: 67921971 - 67923971 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 67921971 - 67923971 | GSE27584 |
chr1 |
Promoter: 67921971 - 67923971 | Agilent_014791_44K |
chr1 |
Promoter: 67921971 - 67923971 | Agilent_014791 |
chr1 |
Promoter: 67921971 - 67923971 | PMID:15735726 |