Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1739

Name

DLG1

Synonymous

DLGH1|SAP-97|SAP97|dJ1061C18.1.1|hdlg;discs, large homolog 1 (Drosophila);DLG1;discs, large homolog 1 (Drosophila)

Definition

disks large homolog 1|presynaptic protein SAP97|synapse-associated protein 97

Position

3q29

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

SAP97(h) --> 4.1G(h) (binding)
EPB41(m.s.) + SAP97(h) <==> EPB41(m.s.):SAP97(h) (binding)
vangl2(h) + SAP97(h) <==> vangl2(h):SAP97(h) (binding)
DLG1(h) --> SAP97(h) (expression).
DLG1(h) --> SAP97-isoform1(h) (expression).
SAP97-isoform2(h) + SAPAP1(h) <==> SAP97-isoform2(h):SAPAP1(h) (binding)
SAP97-isoform2(h) + SAPAP1-isoform1(h) <==> SAP97-isoform2(h):SAPAP1-isoform1(h) (binding)
SAP97-isoform2(h) + SAPAP1-isoform2(h) <==> SAP97-isoform2(h):SAPAP1-isoform2(h) (binding)
NR2A(h) + SAP97-isoform2(h) <==> NR2A(h):SAP97-isoform2(h) (binding)
NR2B(h) + SAP97-isoform2(h) <==> NR2B(h):SAP97-isoform2(h) (binding)
NR2C(h) + SAP97-isoform2(h) <==> NR2C(h):SAP97-isoform2(h) (binding)
NR2D(h) + SAP97-isoform2(h) <==> NR2D(h):SAP97-isoform2(h) (binding)
nNOS-isoform1(h) + SAP97-isoform2(h) <==> nNOS-isoform1(h):SAP97-isoform2(h) (binding)
NR1-isoform1(h) + SAP97-isoform2(h) <==> NR1-isoform1(h):SAP97-isoform2(h) (binding)
DLG1(h) --> SAP97-isoform2(h) (expression).
DLG1(h) --> SAP97-isoform3(h) (expression).
DLG1(h) --> SAP97-isoform4(h) (expression).
DLG1(h) --> SAP97-isoform5(h) (expression).
DLG1(h) --> SAP97-isoform6(h) (expression).
DLG1(h) --> SAP97-isoform7(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

232Phosphoserine (By similarity).Swiss-Prot 53.0
301Phosphoserine (By similarity).Swiss-Prot 53.0
683Phosphothreonine (By similarity).Swiss-Prot 53.0
684Phosphoserine.Swiss-Prot 53.0
687Phosphoserine.Swiss-Prot 53.0
684Phosphoserine15302935Phospho.ELM 6.0
687Phosphoserine15302935;17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 198509344 - 198511344Agilent_014791

chr3

Promoter: 198509344 - 198511344GSE27584


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