| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 1789 |
Name | DNMT3B |
Synonymous | ICF|ICF1|M.HsaIIIB;DNA (cytosine-5-)-methyltransferase 3 beta;DNMT3B;DNA (cytosine-5-)-methyltransferase 3 beta |
Definition | DNA (cytosine-5)-methyltransferase 3B|DNA MTase HsaIIIB|DNA methyltransferase HsaIIIB |
Position | 20q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
DNMT3B(h) --> DNA (cytosine-5)-methyltransferase 3B isoform-1(h) (expression). | hdac2(h) + DNA (cytosine-5)-methyltransferase 3B(h) <==> hdac2(h):DNA (cytosine-5)-methyltransferase 3B(h) (binding) | DNA (cytosine-5)-methyltransferase 3B(h) + SNF2H(h) <==> SNF2H(h):DNA (cytosine-5)-methyltransferase 3B(h) (binding) | Hp1-alpha(h) + DNA (cytosine-5)-methyltransferase 3B(h) <==> Hp1-alpha(h):DNA (cytosine-5)-methyltransferase 3B(h) (binding) | HDAC1(h) + DNA (cytosine-5)-methyltransferase 3B(h) <==> HDAC1(h):DNA (cytosine-5)-methyltransferase 3B(h) (binding) | Dnmt1(h) + DNA (cytosine-5)-methyltransferase 3B(h) <==> Dnmt1(h):DNA (cytosine-5)-methyltransferase 3B(h) (binding) | SNF2H(h) + HDAC1(h) + sin3a(h) + KIF4A(h) + CAPE(h) + SMC4L1(h) + DNA (cytosine-5)-methyltransferase 3B(h) <==> SNF2H(h):HDAC1(h):sin3a(h):KIF4A(h):CAPE(h):SMC4L1(h):DNA (cytosine-5)-methyltransferase 3B(h) (binding) | DNA (cytosine-5)-methyltransferase 3B(h) + AFCP(h) <==> DNA (cytosine-5)-methyltransferase 3B(h):AFCP(h) (binding) | DNMT3B(h) --> DNA (cytosine-5)-methyltransferase 3B(h) (expression). | histone H3(m.s.) + S-adenosylmethionine --DNA (cytosine-5)-methyltransferase 3B(h)--> histone H3(m.s.){metK10} + S-adenosylhomocysteine (methylation) | DNMT3B(h) --> DNA (cytosine-5)-methyltransferase 3B isoform-2(h) (expression). | DNMT3B(h) --> DNA (cytosine-5)-methyltransferase 3B isoform-3(h) (expression). | DNMT3B(h) --> DNA (cytosine-5)-methyltransferase 3B isoform-4(h) (expression). | DNMT3B(h) --> DNA (cytosine-5)-methyltransferase 3B isoform-5(h) (expression). | DNMT3B(h) --> DNA (cytosine-5)-methyltransferase 3B isoform-6(h) (expression). | DNMT3B(h) --> DNMT3B(h) (expression). | hsa-miR-29b --/ DNMT3B(h) (translational repression). | hsa-miR-29c --/ DNMT3B(h) (translational repression). | hsa-miR-29a --/ DNMT3B(h) (translational repression). |
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Post Transcriptional Modification [Top] | |||
There is no record for DNMT3B | |||
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr20 |
Promoter: 30812352 - 30814352 | GoldenGate_Methylation_Cancer_Panel_I |
chr20 |
Promoter: 30812352 - 30814352 | GoldenGate_Methylation_Cancer_Panel_I |
chr20 |
Promoter: 30812352 - 30814352 | GoldenGate_Methylation_Cancer_Panel_I |
chr20 |
Promoter: 30812352 - 30814352 | GSE27584 |
chr20 |
Promoter: 30812352 - 30814352 | GSE27584 |
chr20 |
Promoter: 30829819 - 30831819 | GSE27584 |
chr20 |
Promoter: 30812352 - 30814352 | GSE27584 |
chr20 |
Promoter: 30812352 - 30814352 | Agilent_014791_44K |